以二硫化碳（CS2）为偶联剂的羧酸酯化反应

IF 4.2 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2025-07-11 DOI:10.1039/d5cc02553b

A. Ziyaei Halimehjani , Z. Marjani

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引用次数: 0

摘要

以二硫化碳为偶联剂，开发了一种新的、高效的羧酸与醇酯化反应方法。广泛的脂肪族和芳香族羧酸，包括二羧酸，受保护的氨基酸和脂肪酸，在该方案下具有良好的耐受性，提供优异的产量。该方法的主要优点包括低酒精负荷，极好的定量产率，无金属和酸的条件，中性反应条件，以及简单的处理和纯化过程。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Esterification of carboxylic acids using carbon disulfide (CS2) as a coupling agent†

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Esterification of carboxylic acids using carbon disulfide (CS2) as a coupling agent†

A novel and efficient method for the esterification of carboxylic acids with alcohols has been developed, utilizing carbon disulfide as a coupling agent. A wide range of aliphatic and aromatic carboxylic acids, including dicarboxylic acids, protected amino acids, and fatty acids, are well-tolerated under this protocol, delivering excellent yields. The key advantages of this method include low alcohol loading, excellent to quantitative yields, metal- and acid-free conditions, neutral reaction conditions, as well as a straightforward work-up and purification process.

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来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.