烯烃三组分碳卤化反应中作为碳自由基前体的亚砜酰亚砜

IF 4.2 2区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Chemical Communications Pub Date : 2025-07-11 DOI:10.1039/d5cc02855h

Ning Xian , Jiang Yin , Xiaochen Ji , Huawen Huang

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引用次数: 0

摘要

在此，我们开发了一种新的可见光诱导光氧化还原平台，用于以亚砜酰亚砜为碳自由基前体的烯烃的一般三组分双官能化。该反应利用各种烯烃作为底物，并采用具有成本效益、无毒的金属盐作为卤素供体。该工艺在温和的水条件下进行，不需要酸或碱添加剂，为合成具有优异化学选择性和区域选择性的结构多样的富含C（sp3）的有机卤化物提供了一种简单而环保的策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Sulfoxonium ylides as carbon radical precursors in three-component carbohalogenation of alkenes†

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Sulfoxonium ylides as carbon radical precursors in three-component carbohalogenation of alkenes†

Herein, we developed a novel visible-light-induced photoredox platform for general three-component difunctionalization of alkenes with aqueous sulfoxonium ylides as carbon radical precursors. This reaction utilizes various alkenes as substrates and employs cost-effective, non-toxic metal salts as halogen donors. The process proceeds under mild aqueous conditions without requiring acid or base additives, offering a simple and environmentally benign strategy for the synthesis of structurally diverse C(sp³)-rich organic halides with excellent chemo- and regioselectivity profiles.

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来源期刊

Chemical Communications 化学-化学综合

CiteScore

8.60

自引率

4.10%

发文量

2705

审稿时长

1.4 months

期刊介绍： ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.