{"title":"选择性激光小梁成形术治疗开角型青光眼的临床效果:对眼压控制和航空医学认证的意义。","authors":"Hua Wang, Yan-Yan Zhao, Shan-Shan Cao, Wei Chen, Xin Wang, Yong Liu","doi":"10.1016/j.pdpdt.2025.104717","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>The aim of this study is to evaluate the clinical efficacy and safety of selective laser trabeculoplasty (SLT) in individuals diagnosed with open-angle glaucoma within the military pilot population and to examine its impact on intraocular pressure (IOP) regulation and aeromedical certification status.</div></div><div><h3>Methods</h3><div>A retrospective analysis was conducted using clinical data from four military pilots (eight eyes) who underwent SLT at the Ophthalmology Department of the Air Force Characteristics Medical Center between January 2013 and January 2025. Outcomes assessed included 24 h IOP fluctuations before and after SLT, changes in pharmacological management, and medical certification results.</div></div><div><h3>Results</h3><div>A statistically significant reduction in mean IOP was observed in six eyes following SLT (<em>p</em> < 0.05), with accompanying decreases in both the 24 h peak IOP and IOP fluctuation range (<em>p</em> < 0.05). Among the four cases, two individuals demonstrated a reduction or cessation in the use of IOP-lowering medications. All individuals exhibited stable ocular conditions post-treatment and retained or regained their flight qualification status.</div></div><div><h3>Conclusion</h3><div>Based upon the 4 cases of primary open-angle glaucoma investigated, SLT demonstrated favourable safety and efficacy in lowering IOP and reducing medication dependencey in this cohort. Among military pilots with open-angle glaucoma or ocular hypertension, SLT may be regarded as a viable therapeutic option that supports the maintenance of flight readiness and aeromedical certification.</div></div>","PeriodicalId":20141,"journal":{"name":"Photodiagnosis and Photodynamic Therapy","volume":"55 ","pages":"Article 104717"},"PeriodicalIF":2.6000,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Clinical outcomes of selective laser trabeculoplasty in military pilots with open-angle glaucoma: Implications for intraocular pressure control and aeromedical certification\",\"authors\":\"Hua Wang, Yan-Yan Zhao, Shan-Shan Cao, Wei Chen, Xin Wang, Yong Liu\",\"doi\":\"10.1016/j.pdpdt.2025.104717\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><div>The aim of this study is to evaluate the clinical efficacy and safety of selective laser trabeculoplasty (SLT) in individuals diagnosed with open-angle glaucoma within the military pilot population and to examine its impact on intraocular pressure (IOP) regulation and aeromedical certification status.</div></div><div><h3>Methods</h3><div>A retrospective analysis was conducted using clinical data from four military pilots (eight eyes) who underwent SLT at the Ophthalmology Department of the Air Force Characteristics Medical Center between January 2013 and January 2025. Outcomes assessed included 24 h IOP fluctuations before and after SLT, changes in pharmacological management, and medical certification results.</div></div><div><h3>Results</h3><div>A statistically significant reduction in mean IOP was observed in six eyes following SLT (<em>p</em> < 0.05), with accompanying decreases in both the 24 h peak IOP and IOP fluctuation range (<em>p</em> < 0.05). Among the four cases, two individuals demonstrated a reduction or cessation in the use of IOP-lowering medications. All individuals exhibited stable ocular conditions post-treatment and retained or regained their flight qualification status.</div></div><div><h3>Conclusion</h3><div>Based upon the 4 cases of primary open-angle glaucoma investigated, SLT demonstrated favourable safety and efficacy in lowering IOP and reducing medication dependencey in this cohort. Among military pilots with open-angle glaucoma or ocular hypertension, SLT may be regarded as a viable therapeutic option that supports the maintenance of flight readiness and aeromedical certification.</div></div>\",\"PeriodicalId\":20141,\"journal\":{\"name\":\"Photodiagnosis and Photodynamic Therapy\",\"volume\":\"55 \",\"pages\":\"Article 104717\"},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2025-07-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Photodiagnosis and Photodynamic Therapy\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1572100025002492\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Photodiagnosis and Photodynamic Therapy","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1572100025002492","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
Clinical outcomes of selective laser trabeculoplasty in military pilots with open-angle glaucoma: Implications for intraocular pressure control and aeromedical certification
Objective
The aim of this study is to evaluate the clinical efficacy and safety of selective laser trabeculoplasty (SLT) in individuals diagnosed with open-angle glaucoma within the military pilot population and to examine its impact on intraocular pressure (IOP) regulation and aeromedical certification status.
Methods
A retrospective analysis was conducted using clinical data from four military pilots (eight eyes) who underwent SLT at the Ophthalmology Department of the Air Force Characteristics Medical Center between January 2013 and January 2025. Outcomes assessed included 24 h IOP fluctuations before and after SLT, changes in pharmacological management, and medical certification results.
Results
A statistically significant reduction in mean IOP was observed in six eyes following SLT (p < 0.05), with accompanying decreases in both the 24 h peak IOP and IOP fluctuation range (p < 0.05). Among the four cases, two individuals demonstrated a reduction or cessation in the use of IOP-lowering medications. All individuals exhibited stable ocular conditions post-treatment and retained or regained their flight qualification status.
Conclusion
Based upon the 4 cases of primary open-angle glaucoma investigated, SLT demonstrated favourable safety and efficacy in lowering IOP and reducing medication dependencey in this cohort. Among military pilots with open-angle glaucoma or ocular hypertension, SLT may be regarded as a viable therapeutic option that supports the maintenance of flight readiness and aeromedical certification.
期刊介绍:
Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.