食品和饲料安全中黄曲霉毒素B1控制的当前方法:检测、抑制和缓解。

IF 5.6 2区 生物学
Katarzyna Kępka-Borkowska, Katarzyna Chałaśkiewicz, Magdalena Ogłuszka, Mateusz Borkowski, Adam Lepczyński, Chandra Shekhar Pareek, Rafał Radosław Starzyński, Elżbieta Lichwiarska, Sharmin Sultana, Garima Kalra, Nihal Purohit, Barbara Gralak, Ewa Poławska, Mariusz Pierzchała
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引用次数: 0

摘要

黄曲霉毒素是主要由黄曲霉和寄生曲霉产生的有毒次生代谢物,由于其频繁存在于作物、食物和饲料中,特别是在气候变化条件下,引起了重大的全球健康问题。本文通过分析黄曲霉毒素检测和缓解方面的最新进展,阐述了黄曲霉毒素日益增长的威胁。对生物修复、物理和化学解毒以及真菌生长抑制策略进行了全面的文献综述。还研究了黄曲霉毒素在水系统中的出现情况,以及当前的检测技术、去除过程和监管框架。新兴技术,如分子诊断、免疫测定、生物传感器和色谱方法,讨论了它们改善监测和控制的潜力。主要研究结果强调了结合生物和技术解决方案的综合方法的有效性日益提高,以及基于人工智能的工具和现场检测便携式设备的潜力。智能包装和转基因作物在减少源头污染方面的作用也得到了探讨。总体而言,本综述强调了继续开展跨学科研究和制定可持续的适应性策略以减轻黄曲霉毒素风险的重要性,从而在面临环境挑战时支持食品安全和公众健康。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Current Approaches to Aflatoxin B1 Control in Food and Feed Safety: Detection, Inhibition, and Mitigation.

Aflatoxins, toxic secondary metabolites produced primarily by Aspergillus flavus and Aspergillus parasiticus, pose a significant global health concern due to their frequent presence in crops, food, and feed-especially under climate change conditions. This review addresses the growing threat of aflatoxins by analyzing recent advances in detection and mitigation. A comprehensive literature review was conducted, focusing on bioremediation, physical and chemical detoxification, and fungal growth inhibition strategies. The occurrence of aflatoxins in water systems was also examined, along with current detection techniques, removal processes, and regulatory frameworks. Emerging technologies such as molecular diagnostics, immunoassays, biosensors, and chromatographic methods are discussed for their potential to improve monitoring and control. Key findings highlight the increasing efficacy of integrative approaches combining biological and technological solutions and the potential of AI-based tools and portable devices for on-site detection. Intelligent packaging and transgenic crops are also explored for their role in minimizing contamination at the source. Overall, this review emphasizes the importance of continued interdisciplinary research and the development of sustainable, adaptive strategies to mitigate aflatoxin risks, thereby supporting food safety and public health in the face of environmental challenges.

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来源期刊
自引率
10.70%
发文量
13472
审稿时长
1.7 months
期刊介绍: The International Journal of Molecular Sciences (ISSN 1422-0067) provides an advanced forum for chemistry, molecular physics (chemical physics and physical chemistry) and molecular biology. It publishes research articles, reviews, communications and short notes. Our aim is to encourage scientists to publish their theoretical and experimental results in as much detail as possible. Therefore, there is no restriction on the length of the papers or the number of electronics supplementary files. For articles with computational results, the full experimental details must be provided so that the results can be reproduced. Electronic files regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material (including animated pictures, videos, interactive Excel sheets, software executables and others).
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