三级医疗中心尿路病原体级联报告的适用性：一项针对抗菌药物管理干预的试点研究。

IF 1.4 4区医学 Q4 IMMUNOLOGY

Indian Journal of Medical Microbiology Pub Date : 2025-07-10 DOI:10.1016/j.ijmmb.2025.100921

Maitrayee Narayan, Sarita Mohapatra, Bimal Kumar Das, Hitender Gautam, Seema Sood, Benu Dhawan

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引用次数: 0

摘要

抗菌素耐药性（AMR）是一个日益严重的全球卫生问题，强调需要一个有效的抗菌素管理计划（AMSP）。级联报告在AMSP中起着重要作用。最近在CLSI 2023中引入了级联报告的分级系统，建议限制二线或广谱抗菌药物的报告。方法：在这项试点研究中，根据现有的抗生素谱数据，确定了针对不同组尿路病原体的1级和2级抗生素。在10个月内（2023年3月- 12月）发现尿路病原菌，并按分级系统分析其抗菌药敏试验（AST）模式。结果：在10.6%的显著细菌样本中进行了级联报告，这些分离物大多数属于住院部（IPD），对1级中四种不同类别的抗生素高度敏感。结论：本研究强调级联报告在抗菌药物管理的三级医疗保健中心在印度的范围。

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Applicability of cascade reporting among the uropathogens from a tertiary healthcare center : A pilot study targeting antimicrobial stewardship intervention.

Introduction: Antimicrobial resistance (AMR) is a mounting global health problem underlining the need for an effective antimicrobial stewardship program (AMSP). Cascade reporting holds a major role in AMSP. The recent introduction of a tier system for cascade reporting in CLSI 2023 suggests restricted reporting for second-line or broader-spectrum antimicrobial agents .

Methods: In this pilot study, Tier 1 and Tier 2 antibiotics were identified for different group of uropathogens based on available antibiogram data. Uropathogens with significant bacteriuria were identified over a period of 10 months (March-December, 2023) and their antimicrobial susceptibility testing (AST) pattern was analyzed as per the tier system.

Results: Cascade reporting was done in 10.6% of samples with significant bacteriuria and a majority of these isolates belonged to the in-patient department (IPD) with high susceptibility to four different classes of antibiotics in Tier 1.

Conclusion: This study emphasizes the scope of cascade reporting in antimicrobial stewardship at a tertiary healthcare center in India.

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来源期刊

Indian Journal of Medical Microbiology IMMUNOLOGY-

CiteScore

2.20

自引率

0.00%

发文量

154

审稿时长

73 days

期刊介绍： Manuscripts of high standard in the form of original research, multicentric studies, meta analysis, are accepted. Current reports can be submitted as brief communications. Case reports must include review of current literature, clinical details, outcome and follow up. Letters to the editor must be a comment on or pertain to a manuscript already published in the IJMM or in relation to preliminary communication of a larger study. Review articles, Special Articles or Guest Editorials are accepted on invitation.