1968年至2022年美国先天性心脏病死亡率趋势

IF 1.2 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
Zahra Imran , Taimor Mohammed Khan , Saad Ahmed Waqas , Raheel Ahmed , Abdul Mannan Khan Minhas
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引用次数: 0

摘要

目的:在美国,继发性心脏病(CHD)仍然是婴儿因出生缺陷而死亡的主要原因。我们分析了1968年至2022年间不同年龄、性别和种族的冠心病死亡率的长期趋势。方法采用ICD-8/9/10编码,从CDC WONDER数据库中提取冠心病死亡率数据(1968-2022)。计算每10万人的年龄调整死亡率(AAMRs)和粗死亡率(CMRs)。采用联结点回归评估死亡率的时间趋势,报告年百分比变化(APCs)和平均APCs (AAPCs),置信区间为95% (ci)。结果从1968年到2019年,共记录了234,658例冠心病相关死亡。总体AAMR从每10万人3.2例(1968年)下降到0.8例(2019年)(AAPC: - 2.7%;95% CI:−2.9 ~−2.5)。男性的aamr始终高于女性。种族差异仍然存在,黑人或非裔美国人的下降速度较慢。1岁以下婴儿占冠心病死亡人数的56.0%,死亡率下降幅度最大(AAPC: - 3.2%)。近年来死亡率趋于稳定。结论:在过去的50年里,美国的心脏病死亡率显著下降,尽管自2009年以来进展有所放缓。种族和性别的持续差异强调了公平获得专门的冠心病护理和持续的公共卫生努力的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Trends in congenital heart disease mortality in the United States from 1968 to 2022

Purpose

Congenital heart disease (CHD) remains the leading cause of infant mortality due to birth defects in the United States. We analyzed long-term CHD mortality trends across age, sex, and racial groups from 1968 to 2022.

Methods

We extracted CHD mortality data from the CDC WONDER database (1968–2022), using ICD-8/9/10 codes. Age-adjusted mortality rates (AAMRs) and crude mortality rates (CMRs) were calculated per 100,000 population. Joinpoint regression was used to assess temporal trends in mortality, reporting annual percentage changes (APCs) and average APCs (AAPCs) with 95 % confidence intervals (CIs).

Results

From 1968 to 2019, 234,658 CHD-related deaths were recorded. Overall AAMR declined from 3.2 (1968) to 0.8 (2019) per 100,000 (AAPC: −2.7 %; 95 % CI: −2.9 to −2.5). Males consistently had higher AAMRs than females. Racial disparities persisted, with slower declines among Black or African American individuals. Infants under 1 year accounted for 56.0 % of CHD deaths and showed the steepest mortality decline (AAPC: −3.2 %). Mortality rates plateaued in recent years.

Conclusions

CHD mortality in the U.S. has declined markedly over the past five decades, though progress has slowed since 2009. Persistent disparities by race and sex emphasize the need for equitable access to specialized CHD care and ongoing public health efforts.
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来源期刊
International journal of cardiology. Congenital heart disease
International journal of cardiology. Congenital heart disease Cardiology and Cardiovascular Medicine
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