宏基因组测序对眼内感染患者临床结局的影响：一项多中心随机对照试验

IF 4.1 1区医学 Q1 OPHTHALMOLOGY

American Journal of Ophthalmology Pub Date : 2025-07-11 DOI:10.1016/j.ajo.2025.07.003

Jessica G. Shantha, Kareem Moussa, Wipada Laovirojjanakul, Steven Yeh, Edmund Tsui, Judy L. Chen, Albert T. Vitale, Akbar Shakoor, Marissa Larochelle, Katherine Niemeyer, Akshay Mentreddy, Itamar Livnat, Myra Safo, Wendy Ao, Charlene Choo, Daisy Yan, Lina Zhong, Cindi Chen, Kirsten Da Silva, Amit K. Reddy, Jennifer Lee, Amol Sura, Eric L. Crowell, Ying Qian, Yael Sharon, Armin Hinterwirth, Travis Porco, Benjamin F. Arnold, John Gonzales, Nisha R. Acharya, Thomas M. Lietman, Thuy Doan, OPTICS Study Group

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引用次数: 0

摘要

为了确定是否添加无偏试验，与单独的标准诊断相比，眼内液宏基因组测序在假定的感染性眼内炎症性眼病中导致更好的患者预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

The Effect of Metagenomic Sequencing on Patient Clinical Outcomes for Intraocular Infections: A Multicenter Randomized Controlled Trial

To determine whether the addition of an unbiased test, metagenomic sequencing of intraocular fluid, compared to standard-of-care diagnostics alone, leads to better patient outcomes in presumed infectious intraocular inflammatory eye diseases.

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来源期刊

American Journal of Ophthalmology 医学-眼科学

CiteScore

9.20

自引率

7.10%

发文量

406

审稿时长

36 days

期刊介绍： The American Journal of Ophthalmology is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and visual science specialists describing clinical investigations, clinical observations, and clinically relevant laboratory investigations. Published monthly since 1884, the full text of the American Journal of Ophthalmology and supplementary material are also presented online at www.AJO.com and on ScienceDirect. The American Journal of Ophthalmology publishes Full-Length Articles, Perspectives, Editorials, Correspondences, Books Reports and Announcements. Brief Reports and Case Reports are no longer published. We recommend submitting Brief Reports and Case Reports to our companion publication, the American Journal of Ophthalmology Case Reports. Manuscripts are accepted with the understanding that they have not been and will not be published elsewhere substantially in any format, and that there are no ethical problems with the content or data collection. Authors may be requested to produce the data upon which the manuscript is based and to answer expeditiously any questions about the manuscript or its authors.