无声的威胁:关于铅引起的神经和全身损伤的一系列案例。

IF 0.5 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Rohit Sharma, Mohini Asija, Shaveta Dahiya, H K Aggarwal, Manish Kumar
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引用次数: 0

摘要

铅中毒仍然是一个重大的全球公共卫生问题,具有多种临床表现,受接触途径和持续时间的影响。其表现的复杂性往往使及时诊断和干预困难。本系列病例包括两例:一名来自印度哈里亚纳邦农村的35岁男性,环境铅暴露导致小脑共济失调和小细胞贫血;另一名30岁电池厂工人,职业性铅暴露导致运动神经病变、肾病和贫血。这些病例说明了与铅中毒有关的诊断复杂性,特别是当血清铅水平不能可靠地反映暴露的严重程度时。第一个病例与地下水污染有关,而第二个病例突出了长期工作场所接触的影响,尽管血清铅浓度明显正常。这两个病例在停止接触和螯合治疗后均表现出临床改善,强调了早期识别和干预的重要性。这些病例报告强调了严格的环境法规、职业安全措施和提高临床意识以减轻铅相关发病率的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The silent threat: A case series on lead-induced neurological and systemic damage.

Lead toxicity remains a significant global public health concern, with diverse clinical manifestations influenced by the route and duration of exposure. The complexity of its presentation often makes timely diagnosis and intervention difficult. This case series presents two cases: a 35-year old male from rural Haryana, India, with environmental lead exposure resulting in cerebellar ataxia and microcytic anaemia, and a 30-year old battery factory worker with occupational exposure leading to motor neuropathy, nephropathy, and anaemia. These cases illustrate the diagnostic complexities associated with lead toxicity, particularly when serum lead levels do not reliably reflect the severity of exposure. The first case was linked to groundwater contamination, whereas the second case highlighted the impact of chronic workplace exposure despite apparently normal serum lead concentrations. Both cases demonstrated clinical improvement following exposure cessation and chelation therapy, emphasising the importance of early recognition and intervention. These case reports underscore the necessity of stringent environmental regulations, occupational safety measures, and heightened clinical awareness to mitigate lead-related morbidity.

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来源期刊
Tropical Doctor
Tropical Doctor 医学-公共卫生、环境卫生与职业卫生
CiteScore
1.20
自引率
0.00%
发文量
144
审稿时长
3 months
期刊介绍: The only journal written by and for health workers in low and middle-income countries, Tropical Doctor provides medical expertise and practical advice on how to apply current medical knowledge to the special circumstances of LMIC countries. This journal provides an ideal forum for sharing experiences and establishing best practice, aiding communication between medical professionals in different environments.
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