为瑞士肺癌患者提供基于价值的医疗保健框架——合并常规收集的医院数据的方法学方法。

IF 2.6 3区 综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES
PLoS ONE Pub Date : 2025-07-10 eCollection Date: 2025-01-01 DOI:10.1371/journal.pone.0327814
Michaela Carla Barbier, Katya Galactionova, Mark Lambiris, Leonel Oliveira, Florian Rüter, Dominik Glinz, Jessica Thürmer, Flurina Pletscher, Benjamin Kasenda, Tobias Finazzi, David König, Didier Lardinois, Larissa Conrad, Leonie Mutz, Matthias Schwenkglenks
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引用次数: 0

摘要

背景:基于价值的医疗保健(VBHC)的概念寻求通过考虑成本优化健康结果来最大化患者价值。然而,必要的数据并不容易获得。在瑞士,医院会计与患者结果和治疗数据脱节。我们展示了合并常规医院数据的可行性,包括患者报告的结果测量(PROMs),以在现实世界的肺癌中心实施VBHC的核心要素。方法:我们开发了一种合并方法,使用了2020年6月至2023年11月在巴塞尔大学医院治疗的208例新诊断肺癌患者的记录。患者最长随访时间为12个月。临床报告结果测量(CROM)和PROM数据收集遵循国际健康结果测量联盟(肺癌组)标准。成本数据取自瑞士标准医院会计系统(REKOLE®)。为了说明合并数据提供的分析选项,我们分析了成本和效用从基线变化之间的部分相关性。结果:合并方法成功地将费用分配给特定的肺癌治疗,并将合并症护理的费用分开,使不同护理要素的成本分布能够初步呈现。每位肺癌患者第一年总住院费用中位数为77,834瑞士法郎(平均93,621瑞士法郎)。免疫治疗的中位费用最高,为45,394瑞士法郎(平均49,518瑞士法郎),其次是手术41,665瑞士法郎(平均48,940瑞士法郎)。诊断为第一阶段的患者第一年的费用往往低于晚期患者。开发了一个标准的图形工具来跟踪单个患者的治疗、结果和费用。结论:这一概念验证分析证明了一种新的数据合并方法作为VBHC实施基础的可行性。虽然受样本量和随访时间的限制,我们的方法支持未来的治疗成本-效益模型。它可在其他条件和医院中复制和扩展,使肺癌治疗朝着更高的价值和效率发展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Contributing to a value-based health care framework for lung cancer patients in Switzerland - A methodological approach to merge routinely collected hospital data.

Contributing to a value-based health care framework for lung cancer patients in Switzerland - A methodological approach to merge routinely collected hospital data.

Contributing to a value-based health care framework for lung cancer patients in Switzerland - A methodological approach to merge routinely collected hospital data.

Contributing to a value-based health care framework for lung cancer patients in Switzerland - A methodological approach to merge routinely collected hospital data.

Background: The concept of Value-Based Health Care (VBHC) seeks to maximise patient value by optimising health outcomes considering costs. However, necessary data are not readily available. In Switzerland, hospital accounting is disconnected from patient outcomes and treatment data. We demonstrate the feasibility of merging routine hospital data, including patient-reported outcome measures (PROMs), to implement core elements of VBHC in a real-world lung cancer centre.

Methods: We developed a merging approach using records from 208 newly diagnosed lung cancer patients treated at University Hospital Basel between June 2020 and November 2023. Maximum patient follow-up was 12-months. Clinician-reported outcome measure (CROM) and PROM data collection followed the International Consortium for Health Outcomes Measurement (Lung Cancer Set) standard. Cost data were extracted from Switzerland's standard hospital accounting system (REKOLE®). To illustrate analytical options offered by the merged data, we analysed partial correlations between costs and utility changes from baseline.

Results: The merging approach successfully allocated costs to specific lung cancer treatments and separated costs for comorbidity care, enabling an initial presentation of cost distributions for different elements of care. Median total first-year hospital costs per lung cancer patient were CHF 77,834 (mean CHF 93,621). Immunotherapy incurred the highest median costs of CHF 45,394 (mean CHF 49,518), followed by surgery of CHF 41,665 (mean CHF 48,940). First-year costs for patients diagnosed with stage I tended to be lower than for later stages. A standard graphical tool was developed to track individual patient treatment, outcome, and cost over time.

Conclusions: This proof-of-concept analysis demonstrates the feasibility of a novel data merging approach as a foundation for VBHC implementation. While limited by sample size and follow-up duration, our method supports future treatment-cost-benefit models. It is reproducible and scalable across other conditions and hospitals, enabling the development of lung cancer treatments towards greater value and efficiency.

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来源期刊
PLoS ONE
PLoS ONE 生物-生物学
CiteScore
6.20
自引率
5.40%
发文量
14242
审稿时长
3.7 months
期刊介绍: PLOS ONE is an international, peer-reviewed, open-access, online publication. PLOS ONE welcomes reports on primary research from any scientific discipline. It provides: * Open-access—freely accessible online, authors retain copyright * Fast publication times * Peer review by expert, practicing researchers * Post-publication tools to indicate quality and impact * Community-based dialogue on articles * Worldwide media coverage
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