维生素D与糖尿病:探讨联系、预防和管理。

IF 3.5 4区 医学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY
Geir Bjørklund, Monica Butnariu, Leonard Gurgas, Tony Hangan
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引用次数: 0

摘要

维生素D是一种至关重要的营养素,在健康的各个方面起着重要作用。这篇综述探讨了维生素D及其辅助因子在预防和控制疾病中的重要性,主要集中在糖尿病及其并发症。有证据表明,维生素D水平低与2型糖尿病(T2D)、妊娠糖尿病和1型糖尿病风险增加之间存在密切联系。补充维生素D在减少这些疾病的发病率和改善治疗结果方面显示出令人鼓舞的效果,为抗击糖尿病带来了希望。此外,维生素D缺乏与糖尿病并发症的风险增加有关,包括抑郁症、癌症、周围神经病变和糖尿病足溃疡。充足的维生素D水平已被证明可以预防和治疗这些并发症,改善症状和总体结果。该审查还强调了全球维生素D缺乏症的流行。它探讨了优化维生素D水平的策略,包括阳光照射、饮食来源、补充剂以及镁和维生素K2等辅助因子的作用。它强调了提高对维生素D优化重要性的认识的重要性,以及每个人在实施这些战略中发挥作用的必要性,因为它可以深刻地影响疾病的预防和管理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Vitamin D and Diabetes: Exploring the Link, Prevention, and Management.

Vitamin D is a crucial nutrient that plays a significant role in various aspects of health. This review explores the importance of vitamin D and its cofactors in preventing and managing diseases, mainly focusing on diabetes and its complications. The evidence reveals a strong link between low vitamin D levels and increased risks of type 2 diabetes (T2D), gestational diabetes, and type 1 diabetes. Vitamin D supplementation, which has shown promising results in reducing the incidence of these diseases and improving outcomes, offers hope in the fight against diabetes. Additionally, vitamin D deficiency has been linked to an increased risk of complications in diabetes, including depression, cancer, peripheral neuropathy, and diabetic foot ulcers. Adequate vitamin D levels have been shown to prevent and treat these complications, improving symptoms and overall outcomes. The review also highlights the global vitamin D deficiency pandemic. It explores strategies for optimizing vitamin D levels, including sun exposure, dietary sources, supplementation, and the role of cofactors such as magnesium and vitamin K2. It underscores the importance of raising awareness about the significance of vitamin D optimization and the need for everyone to play a role in implementing these strategies, as it can profoundly impact disease prevention and management.

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来源期刊
Current medicinal chemistry
Current medicinal chemistry 医学-生化与分子生物学
CiteScore
8.60
自引率
2.40%
发文量
468
审稿时长
3 months
期刊介绍: Aims & Scope Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal chemistry. The journal also publishes reviews on recent patents. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.
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