{"title":"抗反流性粘膜切除术：我们的经验和对未来的思考。","authors":"Jean-Christophe N Rwigema, Michael B Ujiki","doi":"10.1007/s11894-025-00992-6","DOIUrl":null,"url":null,"abstract":"<p><p>PURPOSE OF REVIEW: Gastroesophageal reflux disease is prevalent and has a complex pathophysiology. Though medications are first line, a significant proportion of patients are refractory to this treatment and require anti-reflux surgery (ARS). Though surgery has proven safe and effective, most patients and referring providers are reluctant. Anti-Reflux Mucosectomy (ARMS) provides a less invasive alternative treatment option. This review aims to report our experience with ARMS, discuss other technical variations used, and future directions. Recent Findings In our experience, we note improvement in dysphagia with the modified butterfly-shaped mucosal resection, leading to shorter length of stay, quicker recovery, and equivalent QOL outcomes compared to ARS. We note similar efficacy and safety profiles for anti-reflux mucosal ablation, anti-reflux mucosectomy with cap-assisted mucosal resection, peroral endoscopic cardial constriction, and resection and plication. ARMS and its variations show safety and efficacy as alternative non-invasive treatment options for appropriately selected patients with refractory GERD.</p>","PeriodicalId":10776,"journal":{"name":"Current Gastroenterology Reports","volume":"27 1","pages":"51"},"PeriodicalIF":0.0000,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Anti-Reflux Mucosectomy: Our Experience & Thoughts For The Future.\",\"authors\":\"Jean-Christophe N Rwigema, Michael B Ujiki\",\"doi\":\"10.1007/s11894-025-00992-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>PURPOSE OF REVIEW: Gastroesophageal reflux disease is prevalent and has a complex pathophysiology. Though medications are first line, a significant proportion of patients are refractory to this treatment and require anti-reflux surgery (ARS). Though surgery has proven safe and effective, most patients and referring providers are reluctant. Anti-Reflux Mucosectomy (ARMS) provides a less invasive alternative treatment option. This review aims to report our experience with ARMS, discuss other technical variations used, and future directions. Recent Findings In our experience, we note improvement in dysphagia with the modified butterfly-shaped mucosal resection, leading to shorter length of stay, quicker recovery, and equivalent QOL outcomes compared to ARS. We note similar efficacy and safety profiles for anti-reflux mucosal ablation, anti-reflux mucosectomy with cap-assisted mucosal resection, peroral endoscopic cardial constriction, and resection and plication. ARMS and its variations show safety and efficacy as alternative non-invasive treatment options for appropriately selected patients with refractory GERD.</p>\",\"PeriodicalId\":10776,\"journal\":{\"name\":\"Current Gastroenterology Reports\",\"volume\":\"27 1\",\"pages\":\"51\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-07-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Gastroenterology Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s11894-025-00992-6\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Gastroenterology Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s11894-025-00992-6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
Anti-Reflux Mucosectomy: Our Experience & Thoughts For The Future.
PURPOSE OF REVIEW: Gastroesophageal reflux disease is prevalent and has a complex pathophysiology. Though medications are first line, a significant proportion of patients are refractory to this treatment and require anti-reflux surgery (ARS). Though surgery has proven safe and effective, most patients and referring providers are reluctant. Anti-Reflux Mucosectomy (ARMS) provides a less invasive alternative treatment option. This review aims to report our experience with ARMS, discuss other technical variations used, and future directions. Recent Findings In our experience, we note improvement in dysphagia with the modified butterfly-shaped mucosal resection, leading to shorter length of stay, quicker recovery, and equivalent QOL outcomes compared to ARS. We note similar efficacy and safety profiles for anti-reflux mucosal ablation, anti-reflux mucosectomy with cap-assisted mucosal resection, peroral endoscopic cardial constriction, and resection and plication. ARMS and its variations show safety and efficacy as alternative non-invasive treatment options for appropriately selected patients with refractory GERD.
期刊介绍：
As the field of gastroenterology and hepatology rapidly evolves, the wealth of published literature can be overwhelming. The aim of the journal is to help readers stay abreast of such advances by offering authoritative, systematic reviews by leading experts. We accomplish this aim by appointing Section Editors who invite international experts to contribute review articles that highlight recent developments and important papers published in the past year. Major topics in gastroenterology are covered, including pediatric gastroenterology, neuromuscular disorders, infections, nutrition, and inflammatory bowel disease. These reviews provide clear, insightful summaries of expert perspectives relevant to clinical practice. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. We also provide commentaries from well-known figures in the field.
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