Zhiwei Hu, Yongchao Yin, Xiaoli Yang, Hanyang Zhang, Ling Xing, Shiwu Zhang, Xinglong Gong, Ming Wu, Guolin Yun, Shuaishuai Sun
{"title":"利用压力敏感意图识别的上肢运动功能康复系统。","authors":"Zhiwei Hu, Yongchao Yin, Xiaoli Yang, Hanyang Zhang, Ling Xing, Shiwu Zhang, Xinglong Gong, Ming Wu, Guolin Yun, Shuaishuai Sun","doi":"10.1002/advs.202505259","DOIUrl":null,"url":null,"abstract":"<p><p>Functional electrical stimulation (FES) enhances daily living and rehabilitation outcomes for stroke patients but faces challenges in intention recognition, individual adaptability, and closed-loop control. To address these, a reconstruction system is presented for upper limb motor function, employing highly pressure-sensitive liquid metal magnetorheological elastomers (LMMRE) to detect muscle surface pressure. It can dynamically modulate functional electrical stimulation based on muscle force signals, enabling continuous execution of wrist movements for stroke patients. The system markedly improves patient mobility, with wrist lifting angles increased from 14° to 47°, and lifting speed nearly doubled. Clinical trials confirm the system's superior efficacy in promoting motor recovery and reducing muscle spasms. Moreover, functional near-infrared spectroscopy highlights enhanced brain activity and promotes reconstruction of damaged neural pathways during LMMRE-FES therapy compared with the conventional electrical stimulation. This system holds immense potential for advancing stroke rehabilitation, paving the way for portable, wearable devices optimized for home-based care.</p>","PeriodicalId":117,"journal":{"name":"Advanced Science","volume":" ","pages":"e05259"},"PeriodicalIF":14.1000,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Upper Limb Motor Function Rehabilitation System Leveraging Pressure-Sensitive Intent Recognition.\",\"authors\":\"Zhiwei Hu, Yongchao Yin, Xiaoli Yang, Hanyang Zhang, Ling Xing, Shiwu Zhang, Xinglong Gong, Ming Wu, Guolin Yun, Shuaishuai Sun\",\"doi\":\"10.1002/advs.202505259\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Functional electrical stimulation (FES) enhances daily living and rehabilitation outcomes for stroke patients but faces challenges in intention recognition, individual adaptability, and closed-loop control. To address these, a reconstruction system is presented for upper limb motor function, employing highly pressure-sensitive liquid metal magnetorheological elastomers (LMMRE) to detect muscle surface pressure. It can dynamically modulate functional electrical stimulation based on muscle force signals, enabling continuous execution of wrist movements for stroke patients. The system markedly improves patient mobility, with wrist lifting angles increased from 14° to 47°, and lifting speed nearly doubled. Clinical trials confirm the system's superior efficacy in promoting motor recovery and reducing muscle spasms. Moreover, functional near-infrared spectroscopy highlights enhanced brain activity and promotes reconstruction of damaged neural pathways during LMMRE-FES therapy compared with the conventional electrical stimulation. This system holds immense potential for advancing stroke rehabilitation, paving the way for portable, wearable devices optimized for home-based care.</p>\",\"PeriodicalId\":117,\"journal\":{\"name\":\"Advanced Science\",\"volume\":\" \",\"pages\":\"e05259\"},\"PeriodicalIF\":14.1000,\"publicationDate\":\"2025-07-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advanced Science\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://doi.org/10.1002/advs.202505259\",\"RegionNum\":1,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Science","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1002/advs.202505259","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Upper Limb Motor Function Rehabilitation System Leveraging Pressure-Sensitive Intent Recognition.
Functional electrical stimulation (FES) enhances daily living and rehabilitation outcomes for stroke patients but faces challenges in intention recognition, individual adaptability, and closed-loop control. To address these, a reconstruction system is presented for upper limb motor function, employing highly pressure-sensitive liquid metal magnetorheological elastomers (LMMRE) to detect muscle surface pressure. It can dynamically modulate functional electrical stimulation based on muscle force signals, enabling continuous execution of wrist movements for stroke patients. The system markedly improves patient mobility, with wrist lifting angles increased from 14° to 47°, and lifting speed nearly doubled. Clinical trials confirm the system's superior efficacy in promoting motor recovery and reducing muscle spasms. Moreover, functional near-infrared spectroscopy highlights enhanced brain activity and promotes reconstruction of damaged neural pathways during LMMRE-FES therapy compared with the conventional electrical stimulation. This system holds immense potential for advancing stroke rehabilitation, paving the way for portable, wearable devices optimized for home-based care.
期刊介绍:
Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.