老年人自我报告的视力障碍和抑郁症状:纵向中介分析

IF 3.7 2区 医学 Q1 OPHTHALMOLOGY
Ziyin Zhao, Shiyu Wang, Nathan Congdon, Xiaochen Ma
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引用次数: 0

摘要

虽然视力障碍(VI)是老年抑郁症的一个强有力的预测因素,但其潜在机制尚不清楚,特别是在低收入和中等收入国家。本研究旨在探讨中国老年人自我报告的VI与抑郁之间的关联中潜在通路的作用。方法我们纳入了来自中国健康与退休纵向研究的三波数据。我们的分析队列包括7528名年龄在45岁或以上的参与者,平均随访5年。采用反向优势比加权方法进行中介分析,探讨社会参与、身体活动限制和医疗保健可及性的中介作用。结果:自我报告视力障碍的参与者比视力正常的参与者抑郁的几率高31%(调整后OR的95% CI: 1.12, 1.54)。在中介分析中,社会参与和身体活动的中介效应分别为6.3%和21.3%,而通过医疗保健获取的中介效应与0无显著差异。来自这三种中介途径的累积总间接效应估计为β=0.09 (95% CI: 0.04, 0.15),占总效应的26.2%。结论:我们的研究结果表明,自我报告的VI与抑郁症状的关联部分由社会参与和身体活动限制介导。因此,促进日常生活活动的社会参与和康复服务以及工具性日常生活活动是改善视障老年人心理健康状况的潜在干预措施。数据可以在一个公共的、开放访问的存储库中获得。这项研究基于公开可用的数据集。健康数据可从以下网站访问:。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Self-reported vision impairment and depressive symptoms among older adults: a longitudinal mediation analysis
Background Though vision impairment (VI) is a strong predictor for late-life depression, the underlying mechanisms remain unclear, particularly in low-income and middle-income countries. This study aims to investigate the contribution of underlying pathways in mediating the association between self-reported VI and depression among Chinese older adults. Methods We included three waves of data from the China Health and Retirement Longitudinal Study. Our analytical cohort consists of 7528 participants aged 45 years or older with an average follow-up of 5 years. Mediation analyses using the inverse odds ratio weighting approach were conducted to explore the mediating effects of social engagement, limitations in physical activity, and healthcare access. Results Participants with self-reported VI had 31% higher odds (95% CI of adjusted OR: 1.12, 1.54) of depression than those with normal vision. In the mediation analysis, the mediation effects of social engagement and physical activity were 6.3% and 21.3%, respectively, while the mediation effect via healthcare access did not differ significantly from 0. The cumulative total indirect effects stemming from these three mediating pathways were estimated at β=0.09 (95% CI: 0.04, 0.15), accounting for 26.2% of the total effect. Conclusions Our findings suggest that the association of self-reported VI with depressive symptoms was partially mediated by social engagement and physical activity limitations. Therefore, promoting social engagement and rehabilitation services in activities of daily living (ADL) and instrumental ADL are potential interventions to improve mental health status among visually impaired older adults. Data are available in a public, open access repository. This study is based on publicly available datasets. The health data can be accessed from the website: .
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来源期刊
CiteScore
10.30
自引率
2.40%
发文量
213
审稿时长
3-6 weeks
期刊介绍: The British Journal of Ophthalmology (BJO) is an international peer-reviewed journal for ophthalmologists and visual science specialists. BJO publishes clinical investigations, clinical observations, and clinically relevant laboratory investigations related to ophthalmology. It also provides major reviews and also publishes manuscripts covering regional issues in a global context.
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