Lanlan Zheng , Lei You , Shiqi Wu , Shan He , Ke Ning , Jinlin Lei , Chenglin Wang , Guodong Wang , Huibing Han , Huailan Guo , Jing Wang , Yonghong Zhang , Juan Liu , Chen Li
{"title":"植物根系对环境污染物三氯生的回避反应","authors":"Lanlan Zheng , Lei You , Shiqi Wu , Shan He , Ke Ning , Jinlin Lei , Chenglin Wang , Guodong Wang , Huibing Han , Huailan Guo , Jing Wang , Yonghong Zhang , Juan Liu , Chen Li","doi":"10.1016/j.jhazmat.2025.139216","DOIUrl":null,"url":null,"abstract":"<div><div>Triclosan (TCS), an antimicrobial agent commonly found in personal care products and disinfectants, has raised concerns due to its potential risks for human health and environment. In this study, we observed and investigated an avoidance response in Arabidopsis roots, which exhibited directional growth away from TCS-containing medium. Genetic screening of the mutants impaired in salt stress, abscisic acid (ABA), cytokinin, and auxin signaling pathways revealed that polar auxin transport is essential for mediating this TCS-induced root response. Notably, TCS application downregulated the expression level of auxin transporter proteins AUX1 and PIN2 in the root meristem. These findings highlight the regulatory role of polar auxin transport in directing root growth reorientation in response to TCS, enabling plants to avoid from adverse environmental conditions. Deciphering the molecular mechanisms underlying plant responses to environmental pollutants offers valuable insights for developing strategies to reduce pollutant uptake and accumulation in crops, thereby enhancing food safety and supporting human health.</div></div>","PeriodicalId":361,"journal":{"name":"Journal of Hazardous Materials","volume":"496 ","pages":"Article 139216"},"PeriodicalIF":11.3000,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The avoidance response in plant root to the environmental pollutant triclosan\",\"authors\":\"Lanlan Zheng , Lei You , Shiqi Wu , Shan He , Ke Ning , Jinlin Lei , Chenglin Wang , Guodong Wang , Huibing Han , Huailan Guo , Jing Wang , Yonghong Zhang , Juan Liu , Chen Li\",\"doi\":\"10.1016/j.jhazmat.2025.139216\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Triclosan (TCS), an antimicrobial agent commonly found in personal care products and disinfectants, has raised concerns due to its potential risks for human health and environment. In this study, we observed and investigated an avoidance response in Arabidopsis roots, which exhibited directional growth away from TCS-containing medium. Genetic screening of the mutants impaired in salt stress, abscisic acid (ABA), cytokinin, and auxin signaling pathways revealed that polar auxin transport is essential for mediating this TCS-induced root response. Notably, TCS application downregulated the expression level of auxin transporter proteins AUX1 and PIN2 in the root meristem. These findings highlight the regulatory role of polar auxin transport in directing root growth reorientation in response to TCS, enabling plants to avoid from adverse environmental conditions. Deciphering the molecular mechanisms underlying plant responses to environmental pollutants offers valuable insights for developing strategies to reduce pollutant uptake and accumulation in crops, thereby enhancing food safety and supporting human health.</div></div>\",\"PeriodicalId\":361,\"journal\":{\"name\":\"Journal of Hazardous Materials\",\"volume\":\"496 \",\"pages\":\"Article 139216\"},\"PeriodicalIF\":11.3000,\"publicationDate\":\"2025-07-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Hazardous Materials\",\"FirstCategoryId\":\"93\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0304389425021326\",\"RegionNum\":1,\"RegionCategory\":\"环境科学与生态学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ENGINEERING, ENVIRONMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Hazardous Materials","FirstCategoryId":"93","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0304389425021326","RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, ENVIRONMENTAL","Score":null,"Total":0}
The avoidance response in plant root to the environmental pollutant triclosan
Triclosan (TCS), an antimicrobial agent commonly found in personal care products and disinfectants, has raised concerns due to its potential risks for human health and environment. In this study, we observed and investigated an avoidance response in Arabidopsis roots, which exhibited directional growth away from TCS-containing medium. Genetic screening of the mutants impaired in salt stress, abscisic acid (ABA), cytokinin, and auxin signaling pathways revealed that polar auxin transport is essential for mediating this TCS-induced root response. Notably, TCS application downregulated the expression level of auxin transporter proteins AUX1 and PIN2 in the root meristem. These findings highlight the regulatory role of polar auxin transport in directing root growth reorientation in response to TCS, enabling plants to avoid from adverse environmental conditions. Deciphering the molecular mechanisms underlying plant responses to environmental pollutants offers valuable insights for developing strategies to reduce pollutant uptake and accumulation in crops, thereby enhancing food safety and supporting human health.
期刊介绍:
The Journal of Hazardous Materials serves as a global platform for promoting cutting-edge research in the field of Environmental Science and Engineering. Our publication features a wide range of articles, including full-length research papers, review articles, and perspectives, with the aim of enhancing our understanding of the dangers and risks associated with various materials concerning public health and the environment. It is important to note that the term "environmental contaminants" refers specifically to substances that pose hazardous effects through contamination, while excluding those that do not have such impacts on the environment or human health. Moreover, we emphasize the distinction between wastes and hazardous materials in order to provide further clarity on the scope of the journal. We have a keen interest in exploring specific compounds and microbial agents that have adverse effects on the environment.