Megan Partyka, Carolyn Cray, Fabiano Montiani-Ferreira, Jingchao Lan, Sam Rivera
{"title":"临床正常大熊猫急性期蛋白和毛细管区带电泳及与临床患病大熊猫的比较。","authors":"Megan Partyka, Carolyn Cray, Fabiano Montiani-Ferreira, Jingchao Lan, Sam Rivera","doi":"10.1638/2024-0070","DOIUrl":null,"url":null,"abstract":"<p><p>Protein electrophoresis and acute phase proteins are valuable clinical diagnostic tools to identify inflammation. This study evaluated capillary zone electrophoresis (CZE) for clinically normal giant pandas (<i>Ailuropoda melanoleuca</i>) against individuals that were clinically ill. Assay validation for C-reactive protein (CRP), serum amyloid A (SAA), and haptoglobin (HP) was also attempted. Using CZE, total protein, alpha-1 and -2, beta globulins, beta-2 globulins, and gamma globulins were observed to be significantly higher, and albumin:globulin, pre-albumin, and albumin were significantly lower in clinically abnormal giant pandas (<i>p</i> < 0.05). Among the tested APPs, reactivity was only found for CRP reagents and was significantly higher in abnormal giant panda (<i>p</i> = 0.045).</p>","PeriodicalId":17667,"journal":{"name":"Journal of Zoo and Wildlife Medicine","volume":"56 2","pages":"402-409"},"PeriodicalIF":0.7000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"ACUTE PHASE PROTEINS AND CAPILLARY ZONE ELECTROPHORESIS IN CLINICALLY NORMAL GIANT PANDA (<i>AILUROPODA MELANOLEUCA</i>) AND COMPARISON TO CLINICALLY ILL GIANT PANDA.\",\"authors\":\"Megan Partyka, Carolyn Cray, Fabiano Montiani-Ferreira, Jingchao Lan, Sam Rivera\",\"doi\":\"10.1638/2024-0070\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Protein electrophoresis and acute phase proteins are valuable clinical diagnostic tools to identify inflammation. This study evaluated capillary zone electrophoresis (CZE) for clinically normal giant pandas (<i>Ailuropoda melanoleuca</i>) against individuals that were clinically ill. Assay validation for C-reactive protein (CRP), serum amyloid A (SAA), and haptoglobin (HP) was also attempted. Using CZE, total protein, alpha-1 and -2, beta globulins, beta-2 globulins, and gamma globulins were observed to be significantly higher, and albumin:globulin, pre-albumin, and albumin were significantly lower in clinically abnormal giant pandas (<i>p</i> < 0.05). Among the tested APPs, reactivity was only found for CRP reagents and was significantly higher in abnormal giant panda (<i>p</i> = 0.045).</p>\",\"PeriodicalId\":17667,\"journal\":{\"name\":\"Journal of Zoo and Wildlife Medicine\",\"volume\":\"56 2\",\"pages\":\"402-409\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2025-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Zoo and Wildlife Medicine\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.1638/2024-0070\",\"RegionNum\":4,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Zoo and Wildlife Medicine","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1638/2024-0070","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
ACUTE PHASE PROTEINS AND CAPILLARY ZONE ELECTROPHORESIS IN CLINICALLY NORMAL GIANT PANDA (AILUROPODA MELANOLEUCA) AND COMPARISON TO CLINICALLY ILL GIANT PANDA.
Protein electrophoresis and acute phase proteins are valuable clinical diagnostic tools to identify inflammation. This study evaluated capillary zone electrophoresis (CZE) for clinically normal giant pandas (Ailuropoda melanoleuca) against individuals that were clinically ill. Assay validation for C-reactive protein (CRP), serum amyloid A (SAA), and haptoglobin (HP) was also attempted. Using CZE, total protein, alpha-1 and -2, beta globulins, beta-2 globulins, and gamma globulins were observed to be significantly higher, and albumin:globulin, pre-albumin, and albumin were significantly lower in clinically abnormal giant pandas (p < 0.05). Among the tested APPs, reactivity was only found for CRP reagents and was significantly higher in abnormal giant panda (p = 0.045).
期刊介绍：
The Journal of Zoo and Wildlife Medicine (JZWM) is considered one of the major sources of information on the biology and veterinary aspects in the field. It stems from the founding premise of AAZV to share zoo animal medicine experiences. The Journal evolved from the long history of members producing case reports and the increased publication of free-ranging wildlife papers.
The Journal accepts manuscripts of original research findings, case reports in the field of veterinary medicine dealing with captive and free-ranging wild animals, brief communications regarding clinical or research observations that may warrant publication. It also publishes and encourages submission of relevant editorials, reviews, special reports, clinical challenges, abstracts of selected articles and book reviews. The Journal is published quarterly, is peer reviewed, is indexed by the major abstracting services, and is international in scope and distribution.
Areas of interest include clinical medicine, surgery, anatomy, radiology, physiology, reproduction, nutrition, parasitology, microbiology, immunology, pathology (including infectious diseases and clinical pathology), toxicology, pharmacology, and epidemiology.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
