肩胛上神经阻滞局部麻醉与两种不同剂量类固醇治疗颈神经根痛的疗效比较。

IF 1.5 Q3 PHARMACOLOGY & PHARMACY
Naveen Malhotra, Rishabh Anand, Amit Kumar, Neha Sinha, Vaishali Phogat, N Charan
{"title":"肩胛上神经阻滞局部麻醉与两种不同剂量类固醇治疗颈神经根痛的疗效比较。","authors":"Naveen Malhotra, Rishabh Anand, Amit Kumar, Neha Sinha, Vaishali Phogat, N Charan","doi":"10.4103/joacp.joacp_284_24","DOIUrl":null,"url":null,"abstract":"<p><strong>Background and aims: </strong>Neck pain resulting from various cervical spine disorders ranks second among the leading cause of musculoskeletal disorders. This prospective study was conducted to compare the efficacy of suprascapular nerve block (SSNB) using a local anaesthetic and two different doses of dexamethasone in patients with cervical radicular pain.</p><p><strong>Material and methods: </strong>Forty participants were randomised into Group I (n = 20), in which patients received a SSNB with 6 ml of a drug solution comprising 0.25% bupivacaine (4 ml) and 8 mg of dexamethasone (2 ml), and Group II (n = 20), in which patients received SSNB with 6 ml of a drug solution comprising 0.25% bupivacaine (4 ml), 4 mg of dexamethasone (1 ml), and normal saline (1 ml). Patients were followed for a period of six months. The numeric rating scale (NRS), patient global impression of change (PGIC), need for repeat injections, and side effects were compared between the two groups.</p><p><strong>Results: </strong>NRS and PGIC scores were found to be comparable between the two groups at all time intervals (<i>P</i> > 0.05). There was no significant difference amongst the two groups in terms of the number of repeat injections (<i>P</i> > 0.05). None of the patients reported any serious side effects.</p><p><strong>Conclusions: </strong>A SSNB with a local anaesthetic and either 8 mg or 4 mg of dexamethasone is an equally effective technique for managing patients with cervical radicular pain. Hence, a SSNB with 4 mg of dexamethasone can be utilised to reduce the steroid dose without compromising the efficacy and safety of the treatment in patients with cervical radicular pain.</p>","PeriodicalId":14946,"journal":{"name":"Journal of Anaesthesiology, Clinical Pharmacology","volume":"41 3","pages":"491-495"},"PeriodicalIF":1.5000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237184/pdf/","citationCount":"0","resultStr":"{\"title\":\"Comparison of efficacy of suprascapular nerve block using local anaesthetic and two different doses of steroid in cervical radicular pain.\",\"authors\":\"Naveen Malhotra, Rishabh Anand, Amit Kumar, Neha Sinha, Vaishali Phogat, N Charan\",\"doi\":\"10.4103/joacp.joacp_284_24\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background and aims: </strong>Neck pain resulting from various cervical spine disorders ranks second among the leading cause of musculoskeletal disorders. This prospective study was conducted to compare the efficacy of suprascapular nerve block (SSNB) using a local anaesthetic and two different doses of dexamethasone in patients with cervical radicular pain.</p><p><strong>Material and methods: </strong>Forty participants were randomised into Group I (n = 20), in which patients received a SSNB with 6 ml of a drug solution comprising 0.25% bupivacaine (4 ml) and 8 mg of dexamethasone (2 ml), and Group II (n = 20), in which patients received SSNB with 6 ml of a drug solution comprising 0.25% bupivacaine (4 ml), 4 mg of dexamethasone (1 ml), and normal saline (1 ml). Patients were followed for a period of six months. The numeric rating scale (NRS), patient global impression of change (PGIC), need for repeat injections, and side effects were compared between the two groups.</p><p><strong>Results: </strong>NRS and PGIC scores were found to be comparable between the two groups at all time intervals (<i>P</i> > 0.05). There was no significant difference amongst the two groups in terms of the number of repeat injections (<i>P</i> > 0.05). None of the patients reported any serious side effects.</p><p><strong>Conclusions: </strong>A SSNB with a local anaesthetic and either 8 mg or 4 mg of dexamethasone is an equally effective technique for managing patients with cervical radicular pain. Hence, a SSNB with 4 mg of dexamethasone can be utilised to reduce the steroid dose without compromising the efficacy and safety of the treatment in patients with cervical radicular pain.</p>\",\"PeriodicalId\":14946,\"journal\":{\"name\":\"Journal of Anaesthesiology, Clinical Pharmacology\",\"volume\":\"41 3\",\"pages\":\"491-495\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12237184/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Anaesthesiology, Clinical Pharmacology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/joacp.joacp_284_24\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/4/10 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Anaesthesiology, Clinical Pharmacology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/joacp.joacp_284_24","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/10 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0

摘要

背景和目的:由各种颈椎疾病引起的颈部疼痛在肌肉骨骼疾病的主要原因中排名第二。本前瞻性研究旨在比较局部麻醉剂和两种不同剂量地塞米松对颈椎病根性疼痛患者肩胛骨上神经阻滞(SSNB)的疗效。材料和方法:40名参与者随机分为I组(n = 20)和II组(n = 20),其中患者接受SSNB治疗,其中6ml药物溶液包含0.25%布比卡因(4ml)和8mg地塞米松(2ml); II组患者接受SSNB治疗,其中6ml药物溶液包含0.25%布比卡因(4ml), 4mg地塞米松(1ml)和生理盐水(1ml)。对患者进行了为期6个月的随访。比较两组的数值评定量表(NRS)、患者总体印象变化(PGIC)、重复注射需求和副作用。结果:两组患者NRS、PGIC评分在各时间间隔均具有可比性(P < 0.05)。两组重复注射次数比较,差异无统计学意义(P < 0.05)。没有患者报告有任何严重的副作用。结论:SSNB加局部麻醉和8mg或4mg地塞米松是治疗颈根性疼痛患者同样有效的技术。因此,可以使用SSNB加4mg地塞米松来减少类固醇剂量,而不会影响颈根性疼痛患者治疗的有效性和安全性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of efficacy of suprascapular nerve block using local anaesthetic and two different doses of steroid in cervical radicular pain.

Background and aims: Neck pain resulting from various cervical spine disorders ranks second among the leading cause of musculoskeletal disorders. This prospective study was conducted to compare the efficacy of suprascapular nerve block (SSNB) using a local anaesthetic and two different doses of dexamethasone in patients with cervical radicular pain.

Material and methods: Forty participants were randomised into Group I (n = 20), in which patients received a SSNB with 6 ml of a drug solution comprising 0.25% bupivacaine (4 ml) and 8 mg of dexamethasone (2 ml), and Group II (n = 20), in which patients received SSNB with 6 ml of a drug solution comprising 0.25% bupivacaine (4 ml), 4 mg of dexamethasone (1 ml), and normal saline (1 ml). Patients were followed for a period of six months. The numeric rating scale (NRS), patient global impression of change (PGIC), need for repeat injections, and side effects were compared between the two groups.

Results: NRS and PGIC scores were found to be comparable between the two groups at all time intervals (P > 0.05). There was no significant difference amongst the two groups in terms of the number of repeat injections (P > 0.05). None of the patients reported any serious side effects.

Conclusions: A SSNB with a local anaesthetic and either 8 mg or 4 mg of dexamethasone is an equally effective technique for managing patients with cervical radicular pain. Hence, a SSNB with 4 mg of dexamethasone can be utilised to reduce the steroid dose without compromising the efficacy and safety of the treatment in patients with cervical radicular pain.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
1.90
自引率
6.70%
发文量
129
期刊介绍: The JOACP publishes original peer-reviewed research and clinical work in all branches of anaesthesiology, pain, critical care and perioperative medicine including the application to basic sciences. In addition, the journal publishes review articles, special articles, brief communications/reports, case reports, and reports of new equipment, letters to editor, book reviews and obituaries. It is international in scope and comprehensive in coverage.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信