细胞外囊泡的微流体电粘弹性操纵。

IF 2.8 4区生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY

FEBS Open Bio Pub Date : 2025-07-09 DOI:10.1002/2211-5463.70080

Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J Vainio, Caglar Elbuken

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引用次数: 0

摘要

微流控技术为开发生物应用的创新工具创造了新的机会。鉴于细胞外囊泡（EVs）的重要性，广泛的研究集中在开发微流体技术来分离EVs。该研究方案提出了电粘弹性微流体作为操纵电动汽车的新方法。该系统利用悬浮介质的粘弹性以及外部施加的电场来改变微通道内的EV运动。这些结果表明，我们的电粘弹性微流体系统在EV分离方面具有进一步发展的潜力。

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Microfluidic electro-viscoelastic manipulation of extracellular vesicles.

Microfluidic technology has created new opportunities for developing innovative tools for biological applications. Given the significance of extracellular vesicles (EVs), extensive research has focused on developing microfluidic techniques for EV isolation. This research protocol presents electro-viscoelastic microfluidics as a novel approach for manipulating EVs. The system leverages the viscoelasticity of the suspending medium along with an externally applied electric field to alter EV motion within a microchannel. These findings suggest that our electro-viscoelastic microfluidic system has the potential for further development to be used for EV isolation.

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来源期刊

FEBS Open Bio BIOCHEMISTRY & MOLECULAR BIOLOGY-

CiteScore

5.10

自引率

0.00%

发文量

173

审稿时长

10 weeks

期刊介绍： FEBS Open Bio is an online-only open access journal for the rapid publication of research articles in molecular and cellular life sciences in both health and disease. The journal''s peer review process focuses on the technical soundness of papers, leaving the assessment of their impact and importance to the scientific community. FEBS Open Bio is owned by the Federation of European Biochemical Societies (FEBS), a not-for-profit organization, and is published on behalf of FEBS by FEBS Press and Wiley. Any income from the journal will be used to support scientists through fellowships, courses, travel grants, prizes and other FEBS initiatives.