铜催化α，β-不饱和芳基酮双环化制备环五[b]四联胺。

IF 2.7 3区化学 Q1 CHEMISTRY, ORGANIC

Organic & Biomolecular Chemistry Pub Date : 2025-07-04 DOI:10.1039/D5OB00762C

Xia-Run Yao, Hao-Nan Shi, Rong Fu, Ke Chen, Wen-Huan Hao and Bo Jiang

引用次数: 0

摘要

报道了一种铜催化α，β-不饱和芳基酮与α-烯丙基-α-溴羰基双环化合成环五[b]四联胺的简单有效方法。该反应通过c中心自由基引发的5-外三角/6-内三角环化级联进行，为6/6/5碳环骨架的组装提供了一种新的实用方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Copper-catalyzed bi-cyclization of α,β-unsaturated arylketones for accessing cyclopenta[b]tetralines†

查看原文本刊更多论文

Copper-catalyzed bi-cyclization of α,β-unsaturated arylketones for accessing cyclopenta[b]tetralines†

A straightforward and efficient method for the synthesis of cyclopenta[b]tetralines via copper-catalyzed bi-cyclization of α,β-unsaturated arylketones with α-allyl-α-bromocarbonyls has been reported. The reaction proceeds via a C-centered radical-triggered 5-exo-trig/6-endo-trig cyclization cascade and offers a new and practical method for the assembly of 6/6/5 carbocyclic skeletons.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Organic & Biomolecular Chemistry 化学-有机化学

CiteScore

5.50

自引率

9.40%

发文量

1056

审稿时长

1.3 months

期刊介绍： Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.