Muideen T. Olaiya, Joosup Kim, Christopher Pearce, Dominique A. Cadilhac, Nadine E. Andrew, Lauren Sanders, Amanda G. Thrift, Mark R. Nelson, Seana Gall, Monique F. Kilkenny
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引用次数: 0
摘要
目的评价澳大利亚普通实践中卒中二级预防的危险因素管理是否因痴呆状态而异。方法回顾性研究2014年至2018年急性卒中或短暂性脑缺血发作(TIA)的成年人,使用来自澳大利亚卒中临床登记处和维多利亚州三个初级卫生网络的去识别关联数据(2014 - 2020)。入选条件包括出院回家或住院康复,在指数卒中/TIA后慢性期(7-18个月)有两次或两次以上全科就诊。我们评估了卒中/TIA后7-18个月内心脏代谢危险因素(血压、血脂、血糖和尿蛋白)的评估、预防药物的处方和危险因素指标的实现情况。回归模型用于确定风险因素管理的差异。结果在3376例卒中/TIA幸存者中(中位年龄73.9岁,22% TIA), 140例(4%)有痴呆诊断的证据。在多变量分析中,痴呆与被评估的危险因素较少(发病率比[IRR] .86, 95%可信区间[95% CI] CI .76 - 0.98)或处方药物种类(IRR .88, 95% CI .78 - 0.98)相关。在达到危险因素目标方面没有观察到显著差异。结论:尽管痴呆患者很少被评估危险因素或处方卒中二级预防药物,但痴呆状态对危险因素的控制并没有差异。目前的研究结果可能反映了管理接近生命终点的痴呆症患者的适当临床决策。
Primary care management of stroke in people with dementia: Linked registry and general practice data
Objectives
To evaluate whether risk factor management in Australian general practices for secondary prevention of stroke differs by dementia status.
Methods
A retrospective study of adults with acute stroke or transient ischaemic attack (TIA) from 2014 to 2018, using de-identified linked data (2014–2020) from the Australian Stroke Clinical Registry and three Primary Health Networks in Victoria. Eligibility included being discharged home or to inpatient rehabilitation, and having two or more encounters with general practice during the chronic phase (7–18 months) postindex stroke/TIA. We evaluated the assessment of cardiometabolic risk factors (blood pressure, serum lipids, blood glucose and urinary protein), prescription of prevention medications and attainment of risk factor targets, within 7–18 months postindex stroke/TIA. Regression models were used to determine any differences in risk factor management.
Results
Among 3376 eligible survivors of stroke/TIA (median age 73.9 years, 22% TIA), 140 (4%) had evidence of a dementia diagnosis. In multivariable analyses, dementia was associated with fewer risk factors being assessed (incidence rate ratio [IRR] .86, 95% confidence interval [95% CI] CI .76–.98) or medication classes being prescribed (IRR .88, 95% CI .78–.98). No significant difference was observed in the attainment of risk factor targets.
Conclusions
Although patients with dementia were less often assessed for risk factors or prescribed medications for secondary prevention of stroke, the control of risk factors did not differ by dementia status. Current findings may reflect appropriate clinical decision-making for managing people with dementia approaching the end of life.
期刊介绍:
Australasian Journal on Ageing is a peer reviewed journal, which publishes original work in any area of gerontology and geriatric medicine. It welcomes international submissions, particularly from authors in the Asia Pacific region.