吸烟对年龄相关性听力退化的影响：一项使用健康检查的队列研究

IF 3.8 3区医学 Q2 GERIATRICS & GERONTOLOGY

Archives of gerontology and geriatrics Pub Date : 2025-07-07 DOI:10.1016/j.archger.2025.105947

Kensuke Uraguchi , Akiko Sugaya , Etsuji Suzuki , Naomi Matsumoto , Eriko Yanagi , Soshi Takao , Takashi Yorifuji , Mizuo Ando

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引用次数: 0

摘要

目的利用纵向健康检查数据，研究吸烟状况与听力损失之间的关系。方法分析2015 - 2023年在日本香川市竹宫综合医院接受全面健康检查的2349名20岁及以上参与者（9250次健康检查）的数据。使用纯音测听法测量1.0 kHz和4.0 kHz的听力阈值，阈值越高表明听力越差。吸烟状况分为从不吸烟者、既往吸烟者和当前吸烟者（每天10支或≥10支）。采用调整了年龄、性别、职业和病史的多水平线性回归模型来评估听力阈值的基线差异和年度变化。结果在1.0 kHz时，吸烟与听力阈值无显著相关性。然而，在4.0 kHz时，当前吸烟者（≥10支/天）的基线听力较差，与从不吸烟者相比，调整后的阈值增加2.51 dB (p <；0.01)。此外，过去吸烟者和现在吸烟者（≥10支/天）在4.0 kHz时，每年的听力下降速度明显更快，下降0.73 dB/年(p <；0.01)和0.78 dB/年(p <；分别为0.01)。这些发现表明吸烟与高频听力损伤有关，并可能加速与年龄相关的听力损失。在过去的吸烟者中，戒烟的效果并不明显，需要进一步的研究来检验这一假设。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Impact of smoking on age-related deterioration in hearing: A cohort study using health checkups

查看原文本刊更多论文

Impact of smoking on age-related deterioration in hearing: A cohort study using health checkups

Objective

This study aimed to investigate the association between smoking status and hearing loss, both at baseline and annually, using longitudinal health checkup data.

Methods

We analyzed data from 2349 participants (9250 health checkups) aged 20 years and older who underwent comprehensive health checkups at Takinomiya General Hospital in Kagawa, Japan, between 2015 and 2023. Hearing thresholds at 1.0 kHz and 4.0 kHz were measured using pure-tone audiometry, where higher thresholds indicate worse hearing. Smoking status was categorized as never-smoker, past smoker, or current smoker (<10 or ≥10 cigarettes/day). Multilevel linear regression models adjusted for age, sex, occupation, and medical history were used to assess baseline differences and annual changes in hearing thresholds.

Results

At 1.0 kHz, smoking was not significantly associated with hearing thresholds. However, at 4.0 kHz, current smokers (≥10 cigarettes/day) had worse baseline hearing, with an adjusted threshold increase of 2.51 dB compared with never-smokers (p < 0.01). Additionally, past smokers and current smokers (≥10 cigarettes/day) experienced significantly faster deterioration in hearing annually at 4.0 kHz, with reductions of 0.73 dB/year (p < 0.01) and 0.78 dB/year (p < 0.01), respectively.

Discussion

These findings suggest that smoking is associated with high-frequency hearing impairment and may contribute to accelerated age-related hearing loss. The effect of smoking cessation was not evident in past smokers, and further studies are warranted to examine this hypothesis.

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来源期刊

Archives of gerontology and geriatrics 医学-老年医学

CiteScore

7.30

自引率

5.00%

发文量

198

审稿时长

16 days

期刊介绍： Archives of Gerontology and Geriatrics provides a medium for the publication of papers from the fields of experimental gerontology and clinical and social geriatrics. The principal aim of the journal is to facilitate the exchange of information between specialists in these three fields of gerontological research. Experimental papers dealing with the basic mechanisms of aging at molecular, cellular, tissue or organ levels will be published. Clinical papers will be accepted if they provide sufficiently new information or are of fundamental importance for the knowledge of human aging. Purely descriptive clinical papers will be accepted only if the results permit further interpretation. Papers dealing with anti-aging pharmacological preparations in humans are welcome. Papers on the social aspects of geriatrics will be accepted if they are of general interest regarding the epidemiology of aging and the efficiency and working methods of the social organizations for the health care of the elderly.