营养干预对接受颌间固定的颌面部创伤患者总蛋白和白蛋白水平的影响:一项随机对照试验。

Mohamed Azharudeen, Ravindran V, Shahina Kt, Ikram Bin Ismail, Midhun Sai E, Jaslin P A
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引用次数: 0

摘要

背景与目的:上颌下颌固定(MMF)是治疗颌面部骨折的常规固定方法。然而,上颌间固定对术后初期的营养状况提出了挑战,导致水、脂肪和蛋白质储备的消耗。目的是评估在整个治疗期间总蛋白和白蛋白水平在不同间隔的变化,旨在阐明上颌间固定对营养指标的影响。方法:144例在加州政府牙科学院口腔颌面外科就诊的下颌骨折患者,不论病因,均需进行上下颌固定。随机分为两组:营养干预组(组1)和营养不干预组(组2)。测定总蛋白、血清白蛋白等生化指标。测量于MMF开始当天以及之后的第2周和第4周进行。结果:上颌下颌固定(MMF)后,蛋白和白蛋白水平发生显著变化,1组升高,2组降低。结论:本研究强调了个性化营养干预对颌骨骨折行上颌下颌固定(MMF)患者总蛋白和白蛋白水平的显著影响。与非干预组相比,那些接受量身定制的饮食咨询的人在蛋白质和白蛋白水平上都有显著改善。这强调了MMF期间个性化营养支持的重要性,这对组织修复、免疫功能和整体恢复至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of nutritional intervention on total protein and albumin levels in patients with maxillofacial trauma receiving intermaxillary fixation: a randomized controlled trial.

Background and objective: Maxillomandibular fixation (MMF) serves as a conventional approach for immobilizing jaws in the treatment of maxillofacial fractures. However, intermaxillary fixation poses challenges to nutritional status in the immediate postoperative phase, resulting in the depletion of water, fat, and protein reserves. The objective is to evaluate the variations in total protein and albumin levels at distinct intervals throughout the treatment duration, aiming to elucidate the impact of intermaxillary fixation on nutritional markers.

Methodology: A total of 144 patients with jaw fractures presenting to the Oral and Maxillofacial Surgery Department of Govt. Dental College, Calicut, necessitating maxillomandibular fixation, were enrolled irrespective of etiology. They were randomly allocated into two groups: the Nutrition Intervention Group (GROUP 1) and the Nutrition Non-intervention Group (GROUP 2). Biochemical parameters including total protein and serum albumin were assessed. Measurements were conducted on the day of MMF initiation, as well as after the 2nd and 4th weeks thereafter.

Results: Significant variations were observed in the protein and albumin levels, with an increase in group 1 and a decrease in group 2 patients following maxillomandibular fixation (MMF).

Conclusion: This study highlights the significant impact of personalized nutritional intervention on total protein and albumin levels in patients undergoing maxillomandibular fixation (MMF) for jaw fractures. Compared to the non-intervention group, those receiving tailored dietary counselling showed marked improvements in both protein and albumin levels. This emphasizes the importance of individualized nutritional support during MMF, essential for tissue repair, immune function, and overall recovery.

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