重新考虑轻度创伤性脑损伤一年后的认知结果:TRACK-TBI数据的二次分析。

IF 3 3区 心理学 Q2 CLINICAL NEUROLOGY
Summer N Rolin, Audrie A Chavez, Jeremy J Davis
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引用次数: 0

摘要

目的:无并发症的轻度外伤性脑损伤(mTBI)是有时间限制的,有充分记录的自然恢复过程。创伤性脑损伤的转化研究和临床知识(TRACK-TBI)研究结果表明,mTBI后1年的认知预后较差。我们检查了TRACK-TBI数据,考虑了神经成像和性能有效性。方法:TRACK-TBI数据来自联邦机构间创伤性脑损伤研究信息系统。样本(N = 571)包括439例mTBI病史和132例骨科对照。一年的认知结果测量包括听觉语言学习测试总即时(TOT)和延迟回忆(DR),轨迹测试(-A和-B)和WAIS-IV处理速度指数(PSI)。使用先前报告的截止点和研究中的所有测试来检查低分率。使用线性回归检查认知结果的预测因子。结果:1年随访时组间差异极小。虽然对照组的参与者在TOT和DR上得分明显更高,但两组的认知能力在所有测试中都处于正常范围内。两组间TOT和dr的低评分率差异显著。mTBI病史对整体认知能力的预测无显著影响。结论:考虑到效能效度后,非复杂性mTBI与长期认知障碍无关。研究结果强调了在研究和临床环境中区分复杂和非复杂mTBI的重要性。未来的研究可能会用类似的设计来检查心理和功能结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Reconsidering cognitive outcome one year after mild traumatic brain injury: Secondary analysis of TRACK-TBI data.

Objective: Uncomplicated mild traumatic brain injury (mTBI) is time-limited with a well-documented natural course of recovery. Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) findings indicated poor cognitive outcomes 1 year after mTBI. We examined TRACK-TBI data with consideration of neuroimaging and performance validity. Method: TRACK-TBI data were obtained from the Federal Interagency Traumatic Brain Injury Research Informatics System. The sample (N = 571) included 439 cases with mTBI history and 132 orthopedic controls. One-year cognitive outcome measures included Auditory Verbal Learning Test total immediate (TOT) and delayed recall (DR), Trail Making Test (-A and -B), and WAIS-IV Processing Speed Index (PSI). Rates of low scores were examined using previously reported cutoffs and across all tests in the study. Linear regression was used to examine predictors of cognitive outcomes. Results: Group differences at 1-year follow-up were minimal. Although control participants scored significantly higher on TOT and DR, cognitive ability was within normal limits on all tests in both groups. Low score rates were significantly different between groups on TOT and DR. History of mTBI did not significantly contribute to prediction of overall cognitive ability. Conclusions: Uncomplicated mTBI is not associated with long-term cognitive impairment after accounting for performance validity. Findings highlight the importance of distinguishing complicated and uncomplicated mTBI in research and clinical settings. Future studies might examine psychological and functional outcomes with a similar design.

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来源期刊
Clinical Neuropsychologist
Clinical Neuropsychologist 医学-临床神经学
CiteScore
8.40
自引率
12.80%
发文量
61
审稿时长
6-12 weeks
期刊介绍: The Clinical Neuropsychologist (TCN) serves as the premier forum for (1) state-of-the-art clinically-relevant scientific research, (2) in-depth professional discussions of matters germane to evidence-based practice, and (3) clinical case studies in neuropsychology. Of particular interest are papers that can make definitive statements about a given topic (thereby having implications for the standards of clinical practice) and those with the potential to expand today’s clinical frontiers. Research on all age groups, and on both clinical and normal populations, is considered.
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