身体畸形障碍和利培酮滥用:利用高泌乳素血症。

IF 1.4 Q4 PSYCHIATRY
Ömer Faruk Bulut
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引用次数: 0

摘要

本病例报告描述了一名患有身体畸形障碍(BDD)、抽搐和社交障碍的16岁女性,她故意滥用利培酮来利用其高泌乳素血症引起的隆胸,认为这对她的身体形象有益。初用舍曲林治疗可改善社交退缩;然而,辅助利培酮(0.5 mg/天)可减少抽搐和BDD症状。催乳素水平升高(44.85 ng/mL)引发乳房增大、溢乳和继发性闭经。患者不顾医嘱继续服用利培酮。改用阿立哌唑使催乳素水平恢复正常(9.13 ng/mL),并消除了副作用,随访3个月症状得到持续控制。这个案例强调了抗精神病药物副作用的风险,强化了BDD病理,当身体变化与畸形目标一致时,青少年易受药物滥用的影响。据我们所知,这是首例故意滥用利培酮治疗BDD美容性高泌乳素血症的报道。临床医生必须监测催乳素水平,优先考虑保留催乳素的药物(如阿立哌唑),并考虑不良反应如何可能使青少年身体形象障碍持续存在。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Body Dysmorphic Disorder and Risperidone Abuse: Exploiting Hyperprolactinemia.

This case report describes a 16-year-old female with body dysmorphic disorder (BDD), tics, and social withdrawal who intentionally abused risperidone to exploit its hyperprolactinemia-induced breast enlargement, perceiving it as beneficial to her body image. Initial treatment with sertraline improved social withdrawal; however, adjunctive risperidone (0.5 mg/day) reduced tics and BDD symptoms. Elevated prolactin levels (44.85 ng/mL) triggered breast enlargement, galactorrhea, and secondary amenorrhea. The patient continued risperidone despite medical advice to discontinue it. Switching to aripiprazole normalized prolactin levels (9.13 ng/mL) and resolved the side effects, with sustained symptom control at 3-month follow-up. This case highlights the risk of antipsychotic side effects reinforcing BDD pathology and adolescents' vulnerability to medication abuse when somatic changes align with dysmorphic goals. To the best of our knowledge, this is the first report of deliberate risperidone abuse for cosmetic hyperprolactinemia in BDD. Clinicians must monitor prolactin levels, prioritize prolactin-sparing agents (e.g., aripiprazole), and consider how adverse effects may perpetuate body image disturbances in adolescents.

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来源期刊
CiteScore
2.90
自引率
5.00%
发文量
20
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