Rui Hua, Michela Carter, Megan K. O’Brien, J. Benjamin Pitt, Soyang Kwon, Renee C. B. Manworren, Gia Oscherwitz, Arianna Edobor, Austin Chen, Hassan M. K. Ghomrawi, Fizan Abdullah, Arun Jayaraman
{"title":"来自消费者可穿戴设备的生物节律预测儿童术后并发症","authors":"Rui Hua, Michela Carter, Megan K. O’Brien, J. Benjamin Pitt, Soyang Kwon, Renee C. B. Manworren, Gia Oscherwitz, Arianna Edobor, Austin Chen, Hassan M. K. Ghomrawi, Fizan Abdullah, Arun Jayaraman","doi":"10.1126/sciadv.adv2643","DOIUrl":null,"url":null,"abstract":"<div >Postoperative complications pose substantial health risks to children who undergo surgery, yet timely detection of complications after discharge is challenging due to reliance on subjective symptom reports from children and caregivers. Alternatively, wearable devices can provide objective health measurements for continuous recovery monitoring, potentially enabling earlier complication detection in the hospital or community. This study examined biorhythm-based metrics (circadian and ultradian rhythms, derived from the daily activity and heart rate patterns recorded by a consumer wearable) and their relationship to postoperative recovery in children with and without complications. Wearables were given to 103 children for 21 days immediately after appendectomy, and biorhythm metrics were extracted from per-minute data. A machine-learned model using these metrics retrospectively predicted postoperative complications up to 3 days before formal diagnosis with 91% sensitivity and 74% specificity. Our findings suggest that wearable-derived biorhythms offer a promising, unobtrusive method for evaluating postoperative recovery. This approach has broad clinical implications for pediatric health monitoring across various care settings.</div>","PeriodicalId":21609,"journal":{"name":"Science Advances","volume":"11 28","pages":""},"PeriodicalIF":11.7000,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.science.org/doi/reader/10.1126/sciadv.adv2643","citationCount":"0","resultStr":"{\"title\":\"Biorhythms derived from consumer wearables predict postoperative complications in children\",\"authors\":\"Rui Hua, Michela Carter, Megan K. O’Brien, J. Benjamin Pitt, Soyang Kwon, Renee C. B. Manworren, Gia Oscherwitz, Arianna Edobor, Austin Chen, Hassan M. K. Ghomrawi, Fizan Abdullah, Arun Jayaraman\",\"doi\":\"10.1126/sciadv.adv2643\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div >Postoperative complications pose substantial health risks to children who undergo surgery, yet timely detection of complications after discharge is challenging due to reliance on subjective symptom reports from children and caregivers. Alternatively, wearable devices can provide objective health measurements for continuous recovery monitoring, potentially enabling earlier complication detection in the hospital or community. This study examined biorhythm-based metrics (circadian and ultradian rhythms, derived from the daily activity and heart rate patterns recorded by a consumer wearable) and their relationship to postoperative recovery in children with and without complications. Wearables were given to 103 children for 21 days immediately after appendectomy, and biorhythm metrics were extracted from per-minute data. A machine-learned model using these metrics retrospectively predicted postoperative complications up to 3 days before formal diagnosis with 91% sensitivity and 74% specificity. Our findings suggest that wearable-derived biorhythms offer a promising, unobtrusive method for evaluating postoperative recovery. This approach has broad clinical implications for pediatric health monitoring across various care settings.</div>\",\"PeriodicalId\":21609,\"journal\":{\"name\":\"Science Advances\",\"volume\":\"11 28\",\"pages\":\"\"},\"PeriodicalIF\":11.7000,\"publicationDate\":\"2025-07-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.science.org/doi/reader/10.1126/sciadv.adv2643\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Science Advances\",\"FirstCategoryId\":\"103\",\"ListUrlMain\":\"https://www.science.org/doi/10.1126/sciadv.adv2643\",\"RegionNum\":1,\"RegionCategory\":\"综合性期刊\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MULTIDISCIPLINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Science Advances","FirstCategoryId":"103","ListUrlMain":"https://www.science.org/doi/10.1126/sciadv.adv2643","RegionNum":1,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
Biorhythms derived from consumer wearables predict postoperative complications in children
Postoperative complications pose substantial health risks to children who undergo surgery, yet timely detection of complications after discharge is challenging due to reliance on subjective symptom reports from children and caregivers. Alternatively, wearable devices can provide objective health measurements for continuous recovery monitoring, potentially enabling earlier complication detection in the hospital or community. This study examined biorhythm-based metrics (circadian and ultradian rhythms, derived from the daily activity and heart rate patterns recorded by a consumer wearable) and their relationship to postoperative recovery in children with and without complications. Wearables were given to 103 children for 21 days immediately after appendectomy, and biorhythm metrics were extracted from per-minute data. A machine-learned model using these metrics retrospectively predicted postoperative complications up to 3 days before formal diagnosis with 91% sensitivity and 74% specificity. Our findings suggest that wearable-derived biorhythms offer a promising, unobtrusive method for evaluating postoperative recovery. This approach has broad clinical implications for pediatric health monitoring across various care settings.
期刊介绍:
Science Advances, an open-access journal by AAAS, publishes impactful research in diverse scientific areas. It aims for fair, fast, and expert peer review, providing freely accessible research to readers. Led by distinguished scientists, the journal supports AAAS's mission by extending Science magazine's capacity to identify and promote significant advances. Evolving digital publishing technologies play a crucial role in advancing AAAS's global mission for science communication and benefitting humankind.