宿主-微生物共生理论：挑战与机遇

IF 20.6 1区医学 Q1 MICROBIOLOGY

Cell host & microbe Pub Date : 2025-07-09 DOI:10.1016/j.chom.2025.05.001

Pamela Ferretti, Maria M. Martignoni, Lisa C. McManus, Taom Sakal, Armun Liaghat, Bethany Stevens, Kyle J.-M. Dahlin, Lucas S. Souza, Zoe G. Cardon, Cynthia B. Silveira, Seth R. Bordenstein, Joan Roughgarden

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引用次数: 0

摘要

随着对微生物共生现象的深入研究，需要对这些系统进行数学建模。我们讨论了三个需要理论进展的领域：宿主或全息生物内的巢式生态学，全息生物种群动态和共生体介导的物种形成。发展拟议的框架将连接理论和实证发现，加速我们对宿主-微生物共生的理解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Theory of host-microbe symbioses: Challenges and opportunities

Growing insight into microbial symbioses highlights the need to model these systems mathematically. We discuss three areas requiring theoretical advancement: nested ecology within a host or holobiont, holobiont population dynamics, and symbiont-mediated speciation. Developing the proposed frameworks will bridge theory and empirical findings, accelerating our understanding of host-microbe symbioses.

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来源期刊

Cell host & microbe 生物-微生物学

CiteScore

45.10

自引率

1.70%

发文量

201

审稿时长

4-8 weeks

期刊介绍： Cell Host & Microbe is a scientific journal that was launched in March 2007. The journal aims to provide a platform for scientists to exchange ideas and concepts related to the study of microbes and their interaction with host organisms at a molecular, cellular, and immune level. It publishes novel findings on a wide range of microorganisms including bacteria, fungi, parasites, and viruses. The journal focuses on the interface between the microbe and its host, whether the host is a vertebrate, invertebrate, or plant, and whether the microbe is pathogenic, non-pathogenic, or commensal. The integrated study of microbes and their interactions with each other, their host, and the cellular environment they inhabit is a unifying theme of the journal. The published work in Cell Host & Microbe is expected to be of exceptional significance within its field and also of interest to researchers in other areas. In addition to primary research articles, the journal features expert analysis, commentary, and reviews on current topics of interest in the field.