Mahdi Saeidirad , Nooshin Naderi , Saminalsadat Sehat , Fateme Sadat Qazi , Iman Zare , Mahsa Imani , Heemin Kang , Mojdeh Mirshafiei , Morvarid Koohkhezri , Zahra Sadat , Amir Kashtiaray , Mohammad Mahdavi , Reza Eivazzadeh-Keihan , Ali Maleki , Jianliang Shen
{"title":"纳米医学中的明胶集成碳纳米材料:从生物传感和生物打印到组织工程和其他生物医学应用","authors":"Mahdi Saeidirad , Nooshin Naderi , Saminalsadat Sehat , Fateme Sadat Qazi , Iman Zare , Mahsa Imani , Heemin Kang , Mojdeh Mirshafiei , Morvarid Koohkhezri , Zahra Sadat , Amir Kashtiaray , Mohammad Mahdavi , Reza Eivazzadeh-Keihan , Ali Maleki , Jianliang Shen","doi":"10.1016/j.addr.2025.115649","DOIUrl":null,"url":null,"abstract":"<div><div>Carbon nanomaterials (CNMs) in combination with hydrogels (gelatin (Gel)) have shown significant potential in diagnostic and therapeutic applications. This study highlights their significant potential and explores their transformative role in biomedicine. By integrating Gel with CNMs, unique synergistic properties combine mechanical, biocompatibility, and biodegradability properties with the exceptional characteristics of nanomaterials, including high surface area, mechanical strength, and functionalization capabilities. These advanced nanocomposites exhibit remarkable potential across diverse biomedical applications such as cancer therapy, bioprinting applications, tissue engineering and regenerative medicine, wound healing, antimicrobial activity, and bio-packaging. Overall, Gel-integrated CNMs represent a new class of materials with significant promise in advancing biosensing technologies and biomedical performance. Their unique combination of properties opens up new opportunities for the development of next-generation healthcare technologies, improved diagnostics, therapies, and medical devices with enhanced performance and functionality.</div></div>","PeriodicalId":7254,"journal":{"name":"Advanced drug delivery reviews","volume":"224 ","pages":"Article 115649"},"PeriodicalIF":15.2000,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Gelatin-integrated carbon nanomaterials in nanomedicine: From biosensing and bioprinting to tissue engineering and other biomedical applications\",\"authors\":\"Mahdi Saeidirad , Nooshin Naderi , Saminalsadat Sehat , Fateme Sadat Qazi , Iman Zare , Mahsa Imani , Heemin Kang , Mojdeh Mirshafiei , Morvarid Koohkhezri , Zahra Sadat , Amir Kashtiaray , Mohammad Mahdavi , Reza Eivazzadeh-Keihan , Ali Maleki , Jianliang Shen\",\"doi\":\"10.1016/j.addr.2025.115649\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Carbon nanomaterials (CNMs) in combination with hydrogels (gelatin (Gel)) have shown significant potential in diagnostic and therapeutic applications. This study highlights their significant potential and explores their transformative role in biomedicine. By integrating Gel with CNMs, unique synergistic properties combine mechanical, biocompatibility, and biodegradability properties with the exceptional characteristics of nanomaterials, including high surface area, mechanical strength, and functionalization capabilities. These advanced nanocomposites exhibit remarkable potential across diverse biomedical applications such as cancer therapy, bioprinting applications, tissue engineering and regenerative medicine, wound healing, antimicrobial activity, and bio-packaging. Overall, Gel-integrated CNMs represent a new class of materials with significant promise in advancing biosensing technologies and biomedical performance. Their unique combination of properties opens up new opportunities for the development of next-generation healthcare technologies, improved diagnostics, therapies, and medical devices with enhanced performance and functionality.</div></div>\",\"PeriodicalId\":7254,\"journal\":{\"name\":\"Advanced drug delivery reviews\",\"volume\":\"224 \",\"pages\":\"Article 115649\"},\"PeriodicalIF\":15.2000,\"publicationDate\":\"2025-07-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Advanced drug delivery reviews\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0169409X25001346\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced drug delivery reviews","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0169409X25001346","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
Gelatin-integrated carbon nanomaterials in nanomedicine: From biosensing and bioprinting to tissue engineering and other biomedical applications
Carbon nanomaterials (CNMs) in combination with hydrogels (gelatin (Gel)) have shown significant potential in diagnostic and therapeutic applications. This study highlights their significant potential and explores their transformative role in biomedicine. By integrating Gel with CNMs, unique synergistic properties combine mechanical, biocompatibility, and biodegradability properties with the exceptional characteristics of nanomaterials, including high surface area, mechanical strength, and functionalization capabilities. These advanced nanocomposites exhibit remarkable potential across diverse biomedical applications such as cancer therapy, bioprinting applications, tissue engineering and regenerative medicine, wound healing, antimicrobial activity, and bio-packaging. Overall, Gel-integrated CNMs represent a new class of materials with significant promise in advancing biosensing technologies and biomedical performance. Their unique combination of properties opens up new opportunities for the development of next-generation healthcare technologies, improved diagnostics, therapies, and medical devices with enhanced performance and functionality.
期刊介绍:
The aim of the Journal is to provide a forum for the critical analysis of advanced drug and gene delivery systems and their applications in human and veterinary medicine. The Journal has a broad scope, covering the key issues for effective drug and gene delivery, from administration to site-specific delivery.
In general, the Journal publishes review articles in a Theme Issue format. Each Theme Issue provides a comprehensive and critical examination of current and emerging research on the design and development of advanced drug and gene delivery systems and their application to experimental and clinical therapeutics. The goal is to illustrate the pivotal role of a multidisciplinary approach to modern drug delivery, encompassing the application of sound biological and physicochemical principles to the engineering of drug delivery systems to meet the therapeutic need at hand. Importantly the Editorial Team of ADDR asks that the authors effectively window the extensive volume of literature, pick the important contributions and explain their importance, produce a forward looking identification of the challenges facing the field and produce a Conclusions section with expert recommendations to address the issues.