María Camila Castanier-Dávila, Paúl Leonardo Wilches-Coronel
{"title":"自身免疫性疾病患者药物不良反应1例报告","authors":"María Camila Castanier-Dávila, Paúl Leonardo Wilches-Coronel","doi":"10.29262/ram.v72i2.1446","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Adverse drug reactions are harmful and unintentional events related to medication use. Stevens-Johnson Syndrome is a serious adverse drug reaction that can progress to toxic epidermal necrolysis and is related to certain medications. It can even be triggered by infections and genetic factors.</p><p><strong>Case report: </strong>A 62-year-old female patient with high blood pressure developed severe skin lesions after self-medicating with paracetamol and ibuprofen. She recovered favorably after several treatments and admissions to the Intensive Care Unit.</p><p><strong>Conclusion: </strong>It is important to promptly identify the triggering factors of adverse drug reactions in order to intervene appropriately. The administration of corticosteroids and IV immunoglobulin is still under discussion. Immediate attention is required to improve clinical outcomes and comprehensive treatment, thus optimizing the outcome.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 2","pages":"136-141"},"PeriodicalIF":0.0000,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Adverse drug reaction in a patient with autoimmune disease: Case report].\",\"authors\":\"María Camila Castanier-Dávila, Paúl Leonardo Wilches-Coronel\",\"doi\":\"10.29262/ram.v72i2.1446\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Adverse drug reactions are harmful and unintentional events related to medication use. Stevens-Johnson Syndrome is a serious adverse drug reaction that can progress to toxic epidermal necrolysis and is related to certain medications. It can even be triggered by infections and genetic factors.</p><p><strong>Case report: </strong>A 62-year-old female patient with high blood pressure developed severe skin lesions after self-medicating with paracetamol and ibuprofen. She recovered favorably after several treatments and admissions to the Intensive Care Unit.</p><p><strong>Conclusion: </strong>It is important to promptly identify the triggering factors of adverse drug reactions in order to intervene appropriately. The administration of corticosteroids and IV immunoglobulin is still under discussion. Immediate attention is required to improve clinical outcomes and comprehensive treatment, thus optimizing the outcome.</p>\",\"PeriodicalId\":101421,\"journal\":{\"name\":\"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)\",\"volume\":\"72 2\",\"pages\":\"136-141\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-06-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.29262/ram.v72i2.1446\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.29262/ram.v72i2.1446","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Adverse drug reaction in a patient with autoimmune disease: Case report].
Background: Adverse drug reactions are harmful and unintentional events related to medication use. Stevens-Johnson Syndrome is a serious adverse drug reaction that can progress to toxic epidermal necrolysis and is related to certain medications. It can even be triggered by infections and genetic factors.
Case report: A 62-year-old female patient with high blood pressure developed severe skin lesions after self-medicating with paracetamol and ibuprofen. She recovered favorably after several treatments and admissions to the Intensive Care Unit.
Conclusion: It is important to promptly identify the triggering factors of adverse drug reactions in order to intervene appropriately. The administration of corticosteroids and IV immunoglobulin is still under discussion. Immediate attention is required to improve clinical outcomes and comprehensive treatment, thus optimizing the outcome.