如何识别心脏淀粉样变性:附临床病例说明。

Shafag Mustafaeva, Uzeyir Rahimov, Emin Karimli, Khatira Abdulalimova, Shahla Shabanova
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引用次数: 0

摘要

心脏淀粉样变性是一种罕见的全身性疾病,淀粉样蛋白在心脏细胞外积聚。这些蛋白可以沉积在心脏的各个部位,包括瓣膜、心内膜、心肌和心包膜。这种异常的蛋白质沉积可破坏正常的心脏功能,导致一系列症状和并发症,包括心力衰竭、心律失常,甚至心源性猝死。心脏淀粉样变的诊断是基于特征性表现、心电图异常和超声心动图特征来怀疑的,这需要进一步的评估和确认。我们报告一位57岁的女性,因明显的用力呼吸困难、低血压、下肢水肿和蛋白尿而住院。本病例报告的目的是增加临床医生对这种情况的理解,并尽量缩短症状发作和诊断之间的时间间隔,从而潜在地改善受影响患者的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
How to Recognize Cardiac Amyloidosis: Explaining With Clinical Case.

Cardiac amyloidosis is a rare systemic condition in which amyloid proteins accumulate outside the cells of the heart. These proteins can be deposited in various parts of the heart, including the valves, endocardium, myocardium and pericardium. This abnormal protein deposition can disrupt normal heart function, leading to a range of symptoms and complications, including heart failure, arrhythmias, and even sudden cardiac death. Diagnosis of cardiac amyloidosis is suspected based on characteristic findings, electrocardiogram abnormalities, and echocardiographic features, which prompt further evaluation and confirmation. We present the case of a 57-year-old female who was hospitalized due to significant exertional dyspnea, hypotension, lower extremity edema, and proteinuria. The aim of this case report is to augment clinicians' understanding of this condition and to minimize the interval between symptom onset and diagnosis, thereby potentially improving the prognosis of affected patients.

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