S Kay Robert, Neo Chryssa, M Leow Jun, Shalaby Hisham, McKinley John
{"title":"比较使用曼彻斯特-牛津足问卷的患者报告的结果和类风湿关节炎与骨关节炎全踝关节置换术后的手术并发症。","authors":"S Kay Robert, Neo Chryssa, M Leow Jun, Shalaby Hisham, McKinley John","doi":"10.1053/j.jfas.2025.05.019","DOIUrl":null,"url":null,"abstract":"<p><p>Total ankle replacement (TAR) is an alternative to ankle fusion for treatment of end stage ankle arthritis. It has been hypothesized that patients with rheumatoid arthritis may experience inferior outcomes due to altered immune response and low bone quality. Previous studies using the American Orthopaedic Foot & Ankle Society (AOFAS) score suggest patient reported outcomes following TAR for osteoarthritis (OA) versus rheumatoid arthritis (RA) are indifferent, however the AOFAS score has limitations and has largely been superseded by the Manchester-Oxford Foot Questionnaire (MOXFQ) score, which demonstrates favourable data characteristics. The aims of the present study were to compare outcomes in RA versus OA following TAR using the MOXFQ and describe associated complication rates. This single-center cohort study included 114 patients (143 TARs) who underwent primary TAR from 2010 to 2023. Data included patient demographics, comorbidities, satisfaction and MOXFQ. Multivariate logistic regression was used to assess differences in outcomes between OA versus RA adjusting for demographic covariates. Change in MOXFQ score following TAR was equal between the RA and OA group after adjusting for demographic co-variates (OR, 1.01 [95 % CI, 0.99-10.3], p = 0.284). RA was associated with increased risk of wound healing complications (OR 11.75 [95 %CI, 1.06-130.32], p = 0.045). RA status did not influence the likelihood of requiring a revision operation, though this finding lacked sufficient statistical power. RA status was not demonstrated to significantly affect change in MOXFQ score following TAR. Wound healing complications were higher in RA patients, while other surgical and medical complications rates were equivalent.</p>","PeriodicalId":50191,"journal":{"name":"Journal of Foot & Ankle Surgery","volume":" ","pages":""},"PeriodicalIF":1.3000,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparison of patient reported outcomes using the Manchester-Oxford Foot Questionnaire and surgical complications following total ankle replacement in rheumatoid arthritis versus osteoarthritis.\",\"authors\":\"S Kay Robert, Neo Chryssa, M Leow Jun, Shalaby Hisham, McKinley John\",\"doi\":\"10.1053/j.jfas.2025.05.019\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Total ankle replacement (TAR) is an alternative to ankle fusion for treatment of end stage ankle arthritis. It has been hypothesized that patients with rheumatoid arthritis may experience inferior outcomes due to altered immune response and low bone quality. Previous studies using the American Orthopaedic Foot & Ankle Society (AOFAS) score suggest patient reported outcomes following TAR for osteoarthritis (OA) versus rheumatoid arthritis (RA) are indifferent, however the AOFAS score has limitations and has largely been superseded by the Manchester-Oxford Foot Questionnaire (MOXFQ) score, which demonstrates favourable data characteristics. The aims of the present study were to compare outcomes in RA versus OA following TAR using the MOXFQ and describe associated complication rates. This single-center cohort study included 114 patients (143 TARs) who underwent primary TAR from 2010 to 2023. Data included patient demographics, comorbidities, satisfaction and MOXFQ. Multivariate logistic regression was used to assess differences in outcomes between OA versus RA adjusting for demographic covariates. Change in MOXFQ score following TAR was equal between the RA and OA group after adjusting for demographic co-variates (OR, 1.01 [95 % CI, 0.99-10.3], p = 0.284). RA was associated with increased risk of wound healing complications (OR 11.75 [95 %CI, 1.06-130.32], p = 0.045). RA status did not influence the likelihood of requiring a revision operation, though this finding lacked sufficient statistical power. RA status was not demonstrated to significantly affect change in MOXFQ score following TAR. Wound healing complications were higher in RA patients, while other surgical and medical complications rates were equivalent.</p>\",\"PeriodicalId\":50191,\"journal\":{\"name\":\"Journal of Foot & Ankle Surgery\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2025-07-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Foot & Ankle Surgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1053/j.jfas.2025.05.019\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Foot & Ankle Surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1053/j.jfas.2025.05.019","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
Comparison of patient reported outcomes using the Manchester-Oxford Foot Questionnaire and surgical complications following total ankle replacement in rheumatoid arthritis versus osteoarthritis.
Total ankle replacement (TAR) is an alternative to ankle fusion for treatment of end stage ankle arthritis. It has been hypothesized that patients with rheumatoid arthritis may experience inferior outcomes due to altered immune response and low bone quality. Previous studies using the American Orthopaedic Foot & Ankle Society (AOFAS) score suggest patient reported outcomes following TAR for osteoarthritis (OA) versus rheumatoid arthritis (RA) are indifferent, however the AOFAS score has limitations and has largely been superseded by the Manchester-Oxford Foot Questionnaire (MOXFQ) score, which demonstrates favourable data characteristics. The aims of the present study were to compare outcomes in RA versus OA following TAR using the MOXFQ and describe associated complication rates. This single-center cohort study included 114 patients (143 TARs) who underwent primary TAR from 2010 to 2023. Data included patient demographics, comorbidities, satisfaction and MOXFQ. Multivariate logistic regression was used to assess differences in outcomes between OA versus RA adjusting for demographic covariates. Change in MOXFQ score following TAR was equal between the RA and OA group after adjusting for demographic co-variates (OR, 1.01 [95 % CI, 0.99-10.3], p = 0.284). RA was associated with increased risk of wound healing complications (OR 11.75 [95 %CI, 1.06-130.32], p = 0.045). RA status did not influence the likelihood of requiring a revision operation, though this finding lacked sufficient statistical power. RA status was not demonstrated to significantly affect change in MOXFQ score following TAR. Wound healing complications were higher in RA patients, while other surgical and medical complications rates were equivalent.
期刊介绍:
The Journal of Foot & Ankle Surgery is the leading source for original, clinically-focused articles on the surgical and medical management of the foot and ankle. Each bi-monthly, peer-reviewed issue addresses relevant topics to the profession, such as: adult reconstruction of the forefoot; adult reconstruction of the hindfoot and ankle; diabetes; medicine/rheumatology; pediatrics; research; sports medicine; trauma; and tumors.