儿童腹膜周围脓肿:外科和抗菌方法的回顾性分析。

IF 2.6 3区 综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES
PLoS ONE Pub Date : 2025-07-07 eCollection Date: 2025-01-01 DOI:10.1371/journal.pone.0324276
Stefan Alexander Rudhart, Thorsten Send, Maike Tilk, Barbara Leggewie, Franziska Bosse, Klaus Eichhorn, Sebastian Strieth, Stephan Hoch, Alexander Philippe Maas
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引用次数: 0

摘要

背景:扁桃体周围脓肿(PTA)是耳鼻喉科专家和儿科初级保健提供者普遍存在的感染,有可能导致严重的并发症。本研究的目的是探讨小儿腹膜周围脓肿的手术治疗,并比较双侧手术与单侧手术的风险概况。此外,对术中获得的微生物涂片的评估应提供计算的抗生素治疗是否充分覆盖微生物谱的信息。方法:我们对2009年至2024年间接受单侧扁桃体切除术(UTE)或双侧扁桃体切除术(BTE)治疗PTA的儿童患者(n = 150)进行回顾性分析。对患者病历进行分析,包括出血风险、其他并发症的发生、UTE的复发率以及微生物菌群和抗生素治疗情况。结果:两组术后出血无明显差异。在接受UTE治疗的患者中,有4.4%的患者发现PTA复发。术后未见其他严重并发症。抗生素治疗主要依靠头孢呋辛和氨苄西林舒巴坦,符合检测到的微生物菌群。结论:在儿科患者中,UTE和BTE的并发症发生率无相关差异。根据检测到的微生物菌群使用广谱抗生素。自2019年以来,氨苄西林-舒巴坦的计算抗生素治疗一直是儿科PTA的首选治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Peritonsillar abscess in children: A retrospective analysis on surgical and antimicrobial approaches.

Peritonsillar abscess in children: A retrospective analysis on surgical and antimicrobial approaches.

Peritonsillar abscess in children: A retrospective analysis on surgical and antimicrobial approaches.

Peritonsillar abscess in children: A retrospective analysis on surgical and antimicrobial approaches.

Background: Peritonsillar abscess (PTA) is a prevalent infection for specialists in otorhinolaryngology and pediatric primary care providers, that has the potential to cause severe complications. The aim of this study is to investigate the surgical treatment of pediatric peritonsillar abscesses and to compare the risk profiles of bilateral surgery versus surgery on the affected side alone. In addition, the evaluation of the microbiological smears obtained intraoperatively should provide information on whether the calculated antibiotic therapy adequately covers the microbial spectrum.

Methods: We conducted a retrospective analysis of pediatric patients (n = 150), who were treated for PTA between 2009 and 2024 by unilateral tonsillectomy (UTE) or bilateral tonsillectomy (BTE). Patient charts were analyzed regarding risk of bleeding, occurrence of other complications, recurrence rates in case of UTE as well as microbiological flora and antibiotic treatment.

Results: Postoperative bleeding did not differ significantly between both groups. In 4.4% of the patients treated by UTE a recurrent PTA was found. No other severe complications after surgical treatment were found. Antibiotic treatment mainly relied on Cefuroxime and Ampicillin-Sulbactam, which is in accordance with the detected microbiological flora.

Conclusions: No relevant differences were found with regard to the complication rate between UTE und BTE in pediatric patients. Broad-spectrum antibiotics were used in accordance with the detected microbiological flora. Since 2019, calculated antibiotic therapy with Ampicillin-Sulbactam has been the treatment of choice for pediatric PTA.

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来源期刊
PLoS ONE
PLoS ONE 生物-生物学
CiteScore
6.20
自引率
5.40%
发文量
14242
审稿时长
3.7 months
期刊介绍: PLOS ONE is an international, peer-reviewed, open-access, online publication. PLOS ONE welcomes reports on primary research from any scientific discipline. It provides: * Open-access—freely accessible online, authors retain copyright * Fast publication times * Peer review by expert, practicing researchers * Post-publication tools to indicate quality and impact * Community-based dialogue on articles * Worldwide media coverage
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