{"title":"人参皂苷治疗内分泌疾病的潜力：作用和机制。","authors":"Jing Li, Hongyan Qiu, Xiaoxiao Liu, Liang Zhu, Ningning Hou, Xiaodong Sun, Qinying Li","doi":"10.1002/ptr.70033","DOIUrl":null,"url":null,"abstract":"<p><p>Endocrine diseases continue to surge as a global health concern, posing a serious threat to human health and placing a tremendous burden on society. The pathophysiology of endocrine diseases is intricate and multifactorial, often associated with dysregulation in feedback mechanisms or malfunctions within the endocrine system. Numerous studies have been conducted to develop pharmacological agents that prevent or alleviate endocrine disorders. Ginsenosides, the primary bioactive compounds derived from ginseng, exhibit beneficial properties for the treatment and prevention of common endocrine disorders. In this review, we summarize recent research progress on the therapeutic application of ginsenosides in the management of various endocrine disorders. In conclusion, this review aims to provide novel insights into the therapeutic potential and applications of ginsenosides for treating endocrine diseases and to lay a foundation for future clinical studies on ginsenosides.</p>","PeriodicalId":20110,"journal":{"name":"Phytotherapy Research","volume":" ","pages":""},"PeriodicalIF":6.3000,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Therapeutic Potential of Ginsenosides in the Treatment of Endocrine Diseases: Roles and Mechanisms.\",\"authors\":\"Jing Li, Hongyan Qiu, Xiaoxiao Liu, Liang Zhu, Ningning Hou, Xiaodong Sun, Qinying Li\",\"doi\":\"10.1002/ptr.70033\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Endocrine diseases continue to surge as a global health concern, posing a serious threat to human health and placing a tremendous burden on society. The pathophysiology of endocrine diseases is intricate and multifactorial, often associated with dysregulation in feedback mechanisms or malfunctions within the endocrine system. Numerous studies have been conducted to develop pharmacological agents that prevent or alleviate endocrine disorders. Ginsenosides, the primary bioactive compounds derived from ginseng, exhibit beneficial properties for the treatment and prevention of common endocrine disorders. In this review, we summarize recent research progress on the therapeutic application of ginsenosides in the management of various endocrine disorders. In conclusion, this review aims to provide novel insights into the therapeutic potential and applications of ginsenosides for treating endocrine diseases and to lay a foundation for future clinical studies on ginsenosides.</p>\",\"PeriodicalId\":20110,\"journal\":{\"name\":\"Phytotherapy Research\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":6.3000,\"publicationDate\":\"2025-07-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Phytotherapy Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1002/ptr.70033\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MEDICINAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Phytotherapy Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/ptr.70033","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
Therapeutic Potential of Ginsenosides in the Treatment of Endocrine Diseases: Roles and Mechanisms.
Endocrine diseases continue to surge as a global health concern, posing a serious threat to human health and placing a tremendous burden on society. The pathophysiology of endocrine diseases is intricate and multifactorial, often associated with dysregulation in feedback mechanisms or malfunctions within the endocrine system. Numerous studies have been conducted to develop pharmacological agents that prevent or alleviate endocrine disorders. Ginsenosides, the primary bioactive compounds derived from ginseng, exhibit beneficial properties for the treatment and prevention of common endocrine disorders. In this review, we summarize recent research progress on the therapeutic application of ginsenosides in the management of various endocrine disorders. In conclusion, this review aims to provide novel insights into the therapeutic potential and applications of ginsenosides for treating endocrine diseases and to lay a foundation for future clinical studies on ginsenosides.
期刊介绍：
Phytotherapy Research is an internationally recognized pharmacological journal that serves as a trailblazing resource for biochemists, pharmacologists, and toxicologists. We strive to disseminate groundbreaking research on medicinal plants, pushing the boundaries of knowledge and understanding in this field.
Our primary focus areas encompass pharmacology, toxicology, and the clinical applications of herbs and natural products in medicine. We actively encourage submissions on the effects of commonly consumed food ingredients and standardized plant extracts. We welcome a range of contributions including original research papers, review articles, and letters.
By providing a platform for the latest developments and discoveries in phytotherapy, we aim to support the advancement of scientific knowledge and contribute to the improvement of modern medicine.
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