{"title":"前列腺癌放疗期间水凝胶间隔物感染:根治性前列腺切除术成功治疗脓肿1例报告。","authors":"Hiroki Oshiro, Yu Miyazaki, Takuro Kakehi, Masakatsu Hirano, Yusuke Hama, Maki Kanzawa, Sojun Kanamaru","doi":"10.1007/s13691-025-00763-0","DOIUrl":null,"url":null,"abstract":"<p><p>Hydrogel spacers can be inserted to create a gap between the prostate and rectum prior to radiotherapy for prostate cancer, enabling higher radiation doses while reducing rectal toxicity. Spacer infection is relatively rare but significant. We report a case of robot-assisted radical prostatectomy performed for spacer infection and prostate cancer<b>.</b> A 75-year-old man with a hydrogel spacer presented with fatigue and fever after completing 30 Gy of radiation therapy for prostate cancer. He was diagnosed with a periprostatic abscess associated with the hydrogel spacer. Following antibiotic treatment, he underwent robot-assisted radical prostatectomy with concurrent abscess drainage. The treatment outcome was favorable. This case of a radical prostatectomy conducted for spacer infection represents, to our knowledge, the first documented case of management of a hydrogel spacer infection. The favorable treatment outcome suggests that this may be a viable treatment option for similar cases.</p>","PeriodicalId":13703,"journal":{"name":"International Cancer Conference Journal","volume":"14 3","pages":"264-268"},"PeriodicalIF":0.5000,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12229350/pdf/","citationCount":"0","resultStr":"{\"title\":\"Hydrogel spacer infection during prostate cancer radiotherapy: a case report of successful abscess management through radical prostatectomy.\",\"authors\":\"Hiroki Oshiro, Yu Miyazaki, Takuro Kakehi, Masakatsu Hirano, Yusuke Hama, Maki Kanzawa, Sojun Kanamaru\",\"doi\":\"10.1007/s13691-025-00763-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Hydrogel spacers can be inserted to create a gap between the prostate and rectum prior to radiotherapy for prostate cancer, enabling higher radiation doses while reducing rectal toxicity. Spacer infection is relatively rare but significant. We report a case of robot-assisted radical prostatectomy performed for spacer infection and prostate cancer<b>.</b> A 75-year-old man with a hydrogel spacer presented with fatigue and fever after completing 30 Gy of radiation therapy for prostate cancer. He was diagnosed with a periprostatic abscess associated with the hydrogel spacer. Following antibiotic treatment, he underwent robot-assisted radical prostatectomy with concurrent abscess drainage. The treatment outcome was favorable. This case of a radical prostatectomy conducted for spacer infection represents, to our knowledge, the first documented case of management of a hydrogel spacer infection. The favorable treatment outcome suggests that this may be a viable treatment option for similar cases.</p>\",\"PeriodicalId\":13703,\"journal\":{\"name\":\"International Cancer Conference Journal\",\"volume\":\"14 3\",\"pages\":\"264-268\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2025-04-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12229350/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Cancer Conference Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s13691-025-00763-0\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/7/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Cancer Conference Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s13691-025-00763-0","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"ONCOLOGY","Score":null,"Total":0}
Hydrogel spacer infection during prostate cancer radiotherapy: a case report of successful abscess management through radical prostatectomy.
Hydrogel spacers can be inserted to create a gap between the prostate and rectum prior to radiotherapy for prostate cancer, enabling higher radiation doses while reducing rectal toxicity. Spacer infection is relatively rare but significant. We report a case of robot-assisted radical prostatectomy performed for spacer infection and prostate cancer. A 75-year-old man with a hydrogel spacer presented with fatigue and fever after completing 30 Gy of radiation therapy for prostate cancer. He was diagnosed with a periprostatic abscess associated with the hydrogel spacer. Following antibiotic treatment, he underwent robot-assisted radical prostatectomy with concurrent abscess drainage. The treatment outcome was favorable. This case of a radical prostatectomy conducted for spacer infection represents, to our knowledge, the first documented case of management of a hydrogel spacer infection. The favorable treatment outcome suggests that this may be a viable treatment option for similar cases.
期刊介绍:
This online-only journal publishes original case reports on all types of cancer. In particular, we welcome not only case reports of educational value in the diagnosis and treatment of cancers, but also reports on molecularly analyzed cancer cases, including gene mutations, gene fusions, gene expression, and changes in copy number, regardless of their known clinical significance. Assessing the molecular analysis of a tumor usually requires a “cancer conference” in which experts from various fields discuss it. Even if the authors and their respective “cancer conference” were unable to determine the clinical significance of molecular changes at the time of submission and publication, their data may provide evidence that will help the scientific community develop precision medicine solutions in the future. We welcome case reports with reviews of the literature on similar cases, as they are more useful and valuable to readers than are reports of rare cases. International Cancer Conference Journal is the official publication of the Japan Society of Clinical Oncology (JSCO).
- Presents an online-only collection of original case reports on all types of cancer
- In particular, welcomes molecularly analyzed cancer cases
- The Official Publication of the Japan Society of Clinical Oncology (JSCO)