Shinta Trilaksmi Dewi, Nyoman Suryawati, Niken Indrastuti, Dorra Bouazzi, Cecilia E Medianfar, Robin Christensen, Gregor B E Jemec, Nisha S Chandran, Miranti Pangastuti, Aryani Adji, Gardenia Akhyar, Nopriyati Nopriyati, Cut Putri Hazlianda, Sri Awalia Febriana
{"title":"印度尼西亚化脓性汗腺炎的流行：一项横断面多中心研究和筛选问卷的验证。","authors":"Shinta Trilaksmi Dewi, Nyoman Suryawati, Niken Indrastuti, Dorra Bouazzi, Cecilia E Medianfar, Robin Christensen, Gregor B E Jemec, Nisha S Chandran, Miranti Pangastuti, Aryani Adji, Gardenia Akhyar, Nopriyati Nopriyati, Cut Putri Hazlianda, Sri Awalia Febriana","doi":"10.1159/000539705","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Studies on the prevalence of hidradenitis suppurative (HS) in Southeast Asia are scarce, and no studies have been conducted in Indonesia. This study aimed to calculate the prevalence of HS in Indonesia and validate this questionnaire in our population as part of the Global Hidradenitis Suppurativa Atlas (GHiSA) initiative.</p><p><strong>Methods: </strong>This multicenter cross-sectional study was conducted at 7 teaching hospitals in western and central Indonesia from December 2022 to June 2023. A total of 3,237 healthy adults accompanying patients in the outpatient clinics consented to participate. Physicians or nurses delivered the validated screening questionnaire, and photos of the axilla and groin were taken from screen-positive individuals and 10% of the screen-negative individuals. The dermatologist examined the clinical photos to confirm the diagnosis of HS.</p><p><strong>Results: </strong>The prevalence of HS in our study population was 0.43% (14/3,237; with 95% confidence interval [CI]: 0.26%-0.72%), and there was no significant difference in gender, age, body mass index (BMI), and smoking habit between the HS and non-HS groups. In the HS group, males and females were equally affected, with the median age being 29 years with interquartile range (IQR: 24.8-38.5), median BMI of 23.0 (IQR: 21.1-26.4), and 28.6% being smokers. The screening questionnaire showed a sensitivity of 0.43 (6/14; 95% CI: 0.18-0.17), specificity of 0.94 (362/386; 95% CI: 0.91-0.96), positive predictive value of 0.20 (6/30; 95% CI: 0.08-0.39), and negative predictive value of 0.98 (362/370; 95% CI: 0.96-0.99).</p><p><strong>Conclusion: </strong>The prevalence of HS in Indonesia is 0.43%, slightly lower than those reported in other Southeast Asian countries. Age, gender, BMI, and smoking habits were not risk factors for HS in our population. The questionnaire is moderately accurate for screening HS but remains valuable in detecting around 50% of undiagnosed cases.</p>","PeriodicalId":11185,"journal":{"name":"Dermatology","volume":" ","pages":"1-6"},"PeriodicalIF":2.7000,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233964/pdf/","citationCount":"0","resultStr":"{\"title\":\"Hidradenitis Suppurativa Prevalence in Indonesia: A Cross-Sectional Multicenter Study and Validation of a Screening Questionnaire.\",\"authors\":\"Shinta Trilaksmi Dewi, Nyoman Suryawati, Niken Indrastuti, Dorra Bouazzi, Cecilia E Medianfar, Robin Christensen, Gregor B E Jemec, Nisha S Chandran, Miranti Pangastuti, Aryani Adji, Gardenia Akhyar, Nopriyati Nopriyati, Cut Putri Hazlianda, Sri Awalia Febriana\",\"doi\":\"10.1159/000539705\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Studies on the prevalence of hidradenitis suppurative (HS) in Southeast Asia are scarce, and no studies have been conducted in Indonesia. This study aimed to calculate the prevalence of HS in Indonesia and validate this questionnaire in our population as part of the Global Hidradenitis Suppurativa Atlas (GHiSA) initiative.</p><p><strong>Methods: </strong>This multicenter cross-sectional study was conducted at 7 teaching hospitals in western and central Indonesia from December 2022 to June 2023. A total of 3,237 healthy adults accompanying patients in the outpatient clinics consented to participate. Physicians or nurses delivered the validated screening questionnaire, and photos of the axilla and groin were taken from screen-positive individuals and 10% of the screen-negative individuals. The dermatologist examined the clinical photos to confirm the diagnosis of HS.</p><p><strong>Results: </strong>The prevalence of HS in our study population was 0.43% (14/3,237; with 95% confidence interval [CI]: 0.26%-0.72%), and there was no significant difference in gender, age, body mass index (BMI), and smoking habit between the HS and non-HS groups. In the HS group, males and females were equally affected, with the median age being 29 years with interquartile range (IQR: 24.8-38.5), median BMI of 23.0 (IQR: 21.1-26.4), and 28.6% being smokers. The screening questionnaire showed a sensitivity of 0.43 (6/14; 95% CI: 0.18-0.17), specificity of 0.94 (362/386; 95% CI: 0.91-0.96), positive predictive value of 0.20 (6/30; 95% CI: 0.08-0.39), and negative predictive value of 0.98 (362/370; 95% CI: 0.96-0.99).</p><p><strong>Conclusion: </strong>The prevalence of HS in Indonesia is 0.43%, slightly lower than those reported in other Southeast Asian countries. Age, gender, BMI, and smoking habits were not risk factors for HS in our population. The questionnaire is moderately accurate for screening HS but remains valuable in detecting around 50% of undiagnosed cases.</p>\",\"PeriodicalId\":11185,\"journal\":{\"name\":\"Dermatology\",\"volume\":\" \",\"pages\":\"1-6\"},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2025-07-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12233964/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Dermatology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1159/000539705\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dermatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1159/000539705","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DERMATOLOGY","Score":null,"Total":0}
Hidradenitis Suppurativa Prevalence in Indonesia: A Cross-Sectional Multicenter Study and Validation of a Screening Questionnaire.
Introduction: Studies on the prevalence of hidradenitis suppurative (HS) in Southeast Asia are scarce, and no studies have been conducted in Indonesia. This study aimed to calculate the prevalence of HS in Indonesia and validate this questionnaire in our population as part of the Global Hidradenitis Suppurativa Atlas (GHiSA) initiative.
Methods: This multicenter cross-sectional study was conducted at 7 teaching hospitals in western and central Indonesia from December 2022 to June 2023. A total of 3,237 healthy adults accompanying patients in the outpatient clinics consented to participate. Physicians or nurses delivered the validated screening questionnaire, and photos of the axilla and groin were taken from screen-positive individuals and 10% of the screen-negative individuals. The dermatologist examined the clinical photos to confirm the diagnosis of HS.
Results: The prevalence of HS in our study population was 0.43% (14/3,237; with 95% confidence interval [CI]: 0.26%-0.72%), and there was no significant difference in gender, age, body mass index (BMI), and smoking habit between the HS and non-HS groups. In the HS group, males and females were equally affected, with the median age being 29 years with interquartile range (IQR: 24.8-38.5), median BMI of 23.0 (IQR: 21.1-26.4), and 28.6% being smokers. The screening questionnaire showed a sensitivity of 0.43 (6/14; 95% CI: 0.18-0.17), specificity of 0.94 (362/386; 95% CI: 0.91-0.96), positive predictive value of 0.20 (6/30; 95% CI: 0.08-0.39), and negative predictive value of 0.98 (362/370; 95% CI: 0.96-0.99).
Conclusion: The prevalence of HS in Indonesia is 0.43%, slightly lower than those reported in other Southeast Asian countries. Age, gender, BMI, and smoking habits were not risk factors for HS in our population. The questionnaire is moderately accurate for screening HS but remains valuable in detecting around 50% of undiagnosed cases.
期刊介绍：
Published since 1893, ''Dermatology'' provides a worldwide survey of clinical and investigative dermatology. Original papers report clinical and laboratory findings. In order to inform readers of the implications of recent research, editorials and reviews prepared by invited, internationally recognized scientists are regularly featured. In addition to original papers, the journal publishes rapid communications, short communications, and letters to ''Dermatology''. ''Dermatology'' answers the complete information needs of practitioners concerned with progress in research related to skin, clinical dermatology and therapy. The journal enjoys a high scientific reputation with a continually increasing impact factor and an equally high circulation.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
