烟曲霉肺脓肿伴囊性纤维化2例

IF 2.2 4区医学 Q3 MYCOLOGY

Journal de mycologie medicale Pub Date : 2025-07-03 DOI:10.1016/j.mycmed.2025.101570

Maria Noni , Anna Katelari , Konstantinos Iosifidis , Christina Kanaka-Gantenbein , Aristea Velegraki , Georgia Papaioannou , Stavros-Eleftherios Doudounakis

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引用次数: 0

摘要

摘要肺脓肿是非移植性囊性纤维化（CF）患者中一种严重但罕见的并发症。到目前为止，国际文献中已报告了10例病例，细菌被认为是负责任的病原体。我们报告了两例CF青少年患者由烟曲霉引起的肺脓肿，并通过胸部计算机断层扫描发现。在一名患者中，另外检测到甲状腺脓肿。两名患者均出现发热，抗生素治疗无效。微生物培养和分子检测辅助了病原体的检测。两名患者对抗真菌治疗反应良好。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Aspergillus fumigatus lung abscess in two adolescents with cystic fibrosis

Lung abscess is a severe but rare complication among non-transplanted cystic fibrosis (CF) patients. <10 cases have been reported in the international literature so far and bacteria were considered the responsible pathogen. We present two cases of CF adolescent patients who developed lung abscess from A. fumigatus, critically revealed with chest Computed Tomography. In one patient, a thyroid abscess was additionally detected. Both patients presented with fever, not responding to antibiotic therapy. Microbial cultures and molecular testing aided detection of the pathogen. Both patients responded well to antifungal treatment.

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来源期刊

Journal de mycologie medicale 医学-真菌学

CiteScore

5.10

自引率

2.80%

发文量

审稿时长

6-12 weeks

期刊介绍： The Journal de Mycologie Medicale / Journal of Medical Mycology (JMM) publishes in English works dealing with human and animal mycology. The subjects treated are focused in particular on clinical, diagnostic, epidemiological, immunological, medical, pathological, preventive or therapeutic aspects of mycoses. Also covered are basic aspects linked primarily with morphology (electronic and photonic microscopy), physiology, biochemistry, cellular and molecular biology, immunochemistry, genetics, taxonomy or phylogeny of pathogenic or opportunistic fungi and actinomycetes in humans or animals. Studies of natural products showing inhibitory activity against pathogenic fungi cannot be considered without chemical characterization and identification of the compounds responsible for the inhibitory activity. JMM publishes (guest) editorials, original articles, reviews (and minireviews), case reports, technical notes, letters to the editor and information. Only clinical cases with real originality (new species, new clinical present action, new geographical localization, etc.), and fully documented (identification methods, results, etc.), will be considered. Under no circumstances does the journal guarantee publication before the editorial board makes its final decision. The journal is indexed in the main international databases and is accessible worldwide through the ScienceDirect and ClinicalKey platforms.