Alison P. Savo , Vicki Miksicek , Kelsey Brown , Jeffrey R. Applegate Jr
{"title":"新西兰大白兔原发性甲状旁腺功能亢进的诊断和手术治疗","authors":"Alison P. Savo , Vicki Miksicek , Kelsey Brown , Jeffrey R. Applegate Jr","doi":"10.1053/j.jepm.2025.06.001","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Primary hyperparathyroidism is a disorder of the parathyroid gland (s) resulting in excessive secretion of parathyroid hormone, leading to elevated calcium levels. Primary hyperparathyroidism has been poorly described in rabbits.</div></div><div><h3>Case description</h3><div>A 9-year-old male neutered New Zealand white rabbit (<em>Oryctolagus cuniculus</em>) presented for weight loss, inappetence and reduced ambulation. Blood work revealed markedly elevated total calcium (>20mg/dL), ionized calcium (>2.7mmol/L), and PTH (18.10 pmol/L). A cervical ultrasound confirmed the presence of a suspected parathyroid nodule. The patient was anesthetized and a nodulectomy was performed. Hypocalcemia occurred 48 hours post-op, which was managed on a tapering dose of calcitriol. The calcium normalized after 6 weeks of therapy.</div><div>The rabbit also suffered a complete fracture of the right humerus and right shoulder subluxation during recovery. The fracture was surgically stabilized and reduction of the subluxation attempted. The rabbit remained asymptomatic 6 months after presentation.</div></div><div><h3>Conclusions and case relevance</h3><div>Primary hyperparathyroidism should be considered as a differential in rabbits presenting with hypercalcemia. Successful management of this case was achieved via surgical nodulectomy.</div></div>","PeriodicalId":15801,"journal":{"name":"Journal of Exotic Pet Medicine","volume":"54 ","pages":"Pages 21-25"},"PeriodicalIF":0.5000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Diagnosis and surgical management of primary hyperparathyroidism in a New Zealand white rabbit (Oryctolagus cuniculus)\",\"authors\":\"Alison P. Savo , Vicki Miksicek , Kelsey Brown , Jeffrey R. Applegate Jr\",\"doi\":\"10.1053/j.jepm.2025.06.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>Primary hyperparathyroidism is a disorder of the parathyroid gland (s) resulting in excessive secretion of parathyroid hormone, leading to elevated calcium levels. Primary hyperparathyroidism has been poorly described in rabbits.</div></div><div><h3>Case description</h3><div>A 9-year-old male neutered New Zealand white rabbit (<em>Oryctolagus cuniculus</em>) presented for weight loss, inappetence and reduced ambulation. Blood work revealed markedly elevated total calcium (>20mg/dL), ionized calcium (>2.7mmol/L), and PTH (18.10 pmol/L). A cervical ultrasound confirmed the presence of a suspected parathyroid nodule. The patient was anesthetized and a nodulectomy was performed. Hypocalcemia occurred 48 hours post-op, which was managed on a tapering dose of calcitriol. The calcium normalized after 6 weeks of therapy.</div><div>The rabbit also suffered a complete fracture of the right humerus and right shoulder subluxation during recovery. The fracture was surgically stabilized and reduction of the subluxation attempted. The rabbit remained asymptomatic 6 months after presentation.</div></div><div><h3>Conclusions and case relevance</h3><div>Primary hyperparathyroidism should be considered as a differential in rabbits presenting with hypercalcemia. Successful management of this case was achieved via surgical nodulectomy.</div></div>\",\"PeriodicalId\":15801,\"journal\":{\"name\":\"Journal of Exotic Pet Medicine\",\"volume\":\"54 \",\"pages\":\"Pages 21-25\"},\"PeriodicalIF\":0.5000,\"publicationDate\":\"2025-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Exotic Pet Medicine\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1557506325000527\",\"RegionNum\":4,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Exotic Pet Medicine","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1557506325000527","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
Diagnosis and surgical management of primary hyperparathyroidism in a New Zealand white rabbit (Oryctolagus cuniculus)
Background
Primary hyperparathyroidism is a disorder of the parathyroid gland (s) resulting in excessive secretion of parathyroid hormone, leading to elevated calcium levels. Primary hyperparathyroidism has been poorly described in rabbits.
Case description
A 9-year-old male neutered New Zealand white rabbit (Oryctolagus cuniculus) presented for weight loss, inappetence and reduced ambulation. Blood work revealed markedly elevated total calcium (>20mg/dL), ionized calcium (>2.7mmol/L), and PTH (18.10 pmol/L). A cervical ultrasound confirmed the presence of a suspected parathyroid nodule. The patient was anesthetized and a nodulectomy was performed. Hypocalcemia occurred 48 hours post-op, which was managed on a tapering dose of calcitriol. The calcium normalized after 6 weeks of therapy.
The rabbit also suffered a complete fracture of the right humerus and right shoulder subluxation during recovery. The fracture was surgically stabilized and reduction of the subluxation attempted. The rabbit remained asymptomatic 6 months after presentation.
Conclusions and case relevance
Primary hyperparathyroidism should be considered as a differential in rabbits presenting with hypercalcemia. Successful management of this case was achieved via surgical nodulectomy.
期刊介绍:
The Journal of Exotic Pet Medicine provides clinicians with a convenient, comprehensive, "must have" resource to enhance and elevate their expertise with exotic pet medicine. Each issue contains wide ranging peer-reviewed articles that cover many of the current and novel topics important to clinicians caring for exotic pets. Diagnostic challenges, consensus articles and selected review articles are also included to help keep veterinarians up to date on issues affecting their practice. In addition, the Journal of Exotic Pet Medicine serves as the official publication of both the Association of Exotic Mammal Veterinarians (AEMV) and the European Association of Avian Veterinarians (EAAV). The Journal of Exotic Pet Medicine is the most complete resource for practitioners who treat exotic pets.