新西兰大白兔原发性甲状旁腺功能亢进的诊断和手术治疗

IF 0.5 4区 农林科学 Q4 VETERINARY SCIENCES
Alison P. Savo , Vicki Miksicek , Kelsey Brown , Jeffrey R. Applegate Jr
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引用次数: 0

摘要

背景原发性甲状旁腺功能亢进是一种甲状旁腺疾病,导致甲状旁腺激素分泌过多,导致钙水平升高。原发性甲状旁腺功能亢进症在家兔中鲜有报道。病例描述:一只9岁雄性绝育新西兰白兔(Oryctolagus cuniculus)出现体重减轻、食欲不振和行动减少。血液检查显示总钙(20mg/dL)、离子钙(2.7mmol/L)和甲状旁腺激素(18.10 pmol/L)明显升高。宫颈超声检查证实疑似甲状旁腺结节。患者麻醉后行结节切除术。术后48小时出现低钙血症,使用逐渐减少剂量的骨化三醇进行治疗。治疗6周后钙恢复正常。在康复过程中,这只兔子还发生了右肱骨完全骨折和右肩半脱位。手术稳定骨折并尝试复位半脱位。兔在发病后6个月仍无症状。结论和病例相关性原发性甲状旁腺功能亢进应被视为兔高钙血症的鉴别指标。通过手术根瘤切除术成功治疗了该病例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Diagnosis and surgical management of primary hyperparathyroidism in a New Zealand white rabbit (Oryctolagus cuniculus)

Background

Primary hyperparathyroidism is a disorder of the parathyroid gland (s) resulting in excessive secretion of parathyroid hormone, leading to elevated calcium levels. Primary hyperparathyroidism has been poorly described in rabbits.

Case description

A 9-year-old male neutered New Zealand white rabbit (Oryctolagus cuniculus) presented for weight loss, inappetence and reduced ambulation. Blood work revealed markedly elevated total calcium (>20mg/dL), ionized calcium (>2.7mmol/L), and PTH (18.10 pmol/L). A cervical ultrasound confirmed the presence of a suspected parathyroid nodule. The patient was anesthetized and a nodulectomy was performed. Hypocalcemia occurred 48 hours post-op, which was managed on a tapering dose of calcitriol. The calcium normalized after 6 weeks of therapy.
The rabbit also suffered a complete fracture of the right humerus and right shoulder subluxation during recovery. The fracture was surgically stabilized and reduction of the subluxation attempted. The rabbit remained asymptomatic 6 months after presentation.

Conclusions and case relevance

Primary hyperparathyroidism should be considered as a differential in rabbits presenting with hypercalcemia. Successful management of this case was achieved via surgical nodulectomy.
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来源期刊
Journal of Exotic Pet Medicine
Journal of Exotic Pet Medicine 农林科学-兽医学
CiteScore
1.20
自引率
0.00%
发文量
65
审稿时长
60 days
期刊介绍: The Journal of Exotic Pet Medicine provides clinicians with a convenient, comprehensive, "must have" resource to enhance and elevate their expertise with exotic pet medicine. Each issue contains wide ranging peer-reviewed articles that cover many of the current and novel topics important to clinicians caring for exotic pets. Diagnostic challenges, consensus articles and selected review articles are also included to help keep veterinarians up to date on issues affecting their practice. In addition, the Journal of Exotic Pet Medicine serves as the official publication of both the Association of Exotic Mammal Veterinarians (AEMV) and the European Association of Avian Veterinarians (EAAV). The Journal of Exotic Pet Medicine is the most complete resource for practitioners who treat exotic pets.
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