有或没有共同发生的精神健康状况和创伤史的自闭症青少年中物质使用障碍的患病率。

IF 5.6 2区 医学 Q1 BEHAVIORAL SCIENCES
Autism Research Pub Date : 2025-07-07 DOI:10.1002/aur.70081
Jeanette M. Garcia, Kristy A. Anderson, John R. Moore, Tanya Renn, Jessica E. Rast
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引用次数: 0

摘要

关于自闭症青少年中物质使用障碍(sud)患病率的研究有限。此外,虽然精神健康状况和创伤史与非自闭症青少年中SUD的较高患病率有关,但对自闭症青少年的研究很少。因此,本研究的目的是研究自闭症青少年与同时存在心理健康状况和不良童年经历的非自闭症青少年中sud的患病率。来自22,828名自闭症青少年和601,348名非自闭症青少年的数据来自儿童和照顾者相关利用和结果数据库(CCOULD)。使用分类ICD-10诊断代码确定sud,精神健康合并症包括六种情况(ADHD、焦虑、抑郁、双相情感障碍、精神分裂症/精神障碍、创伤/压力相关障碍)、证实的虐待指控和安置史。自闭症青少年的SUD总体患病率(1.7%)低于非自闭症青少年(3.8%)
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence of Substance Use Disorder Among Autistic Youth With and Without Co-Occurring Mental Health Conditions and a History of Trauma

There is limited research on the prevalence of substance use disorders (SUDs) in autistic youth. Additionally, while mental health conditions and history of trauma have been associated with a higher prevalence of SUD in non-autistic youth, the research in autistic youth is scarce. Therefore, the purpose of this study was to examine the prevalence of SUDs in autistic youth compared to non-autistic youth with co-occurring mental health conditions and adverse childhood experiences. Data from 22,828 autistic youth and 601,348 non-autistic youth were drawn from the Child and Caregiver Linked Utilization and Outcomes Database (CCOULD). SUDs were identified using categorized ICD-10 diagnostic codes, and mental health comorbidities included six conditions (ADHD, anxiety, depression, bipolar disorder, schizophrenia/psychotic disorders, trauma/stress-related disorders), substantiated maltreatment allegations, and placement history. Overall prevalence of SUD was lower among autistic youth (1.7%) compared to non-autistic youth (3.8%, p < 0.001). Both mental health comorbidities and maltreatment allegations were significantly associated with having a SUD, regardless of autism diagnosis. Placement in out-of-home care significantly reduced the likelihood of SUD among non-autistic youth (UOR = 0.83, 95% CI: 0.80–0.87) but more than doubled the odds among autistic youth (UOR = 2.36, 95% CI: 1.88–2.97). While prevalence rates of SUDs are lower in autistic youth compared to non-autistic youth, the presence of co-occurring mental health conditions and adverse childhood experiences may increase SUD rates to a greater extent in autistic youth. Future research should further investigate the complex relationships among SUDs, adverse childhood experiences, and mental health conditions in autistic youth.

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来源期刊
Autism Research
Autism Research 医学-行为科学
CiteScore
8.00
自引率
8.50%
发文量
187
审稿时长
>12 weeks
期刊介绍: AUTISM RESEARCH will cover the developmental disorders known as Pervasive Developmental Disorders (or autism spectrum disorders – ASDs). The Journal focuses on basic genetic, neurobiological and psychological mechanisms and how these influence developmental processes in ASDs.
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