[颞下颌关节骨髓水肿研究进展]。

Q4 Medicine
Q Ning, H H Liu, L Q Xu, M Hu
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引用次数: 0

摘要

颞下颌关节骨髓水肿(Bone marrow edema, BME)是骨髓的一种异常改变,在MRI上表现为t1加权低信号,t2加权高信号。常见于颞下颌关节骨关节炎患者。研究表明,BME与关节疼痛、椎间盘移位、骨退变密切相关,但其具体机制尚不完全清楚,可能涉及机械负荷异常、炎症反应和骨代谢失衡。尽管BME被认为是骨关节炎的早期症状,但约71.4%的患者在疼痛缓解后仍持续存在BME,这表明其与临床症状的关联非常复杂。近年来,先进的MRI技术(如T2定位和脂肪抑制序列)提高了BME的检出率,有助于评估其动态变化。然而,BME在颞下颌疾病中的确切作用仍然存在争议。本文就颞下颌关节BME的病因机制、病理、影像学特征及其与临床症状的相关性进行综述,并提出未来的研究方向,以进一步揭示其在疾病进展中的意义,为临床诊治提供指导。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Research progress in bone marrow edema in the temporomandibular joint].

Bone marrow edema (BME) of the temporomandibular joint is an abnormal change within the bone marrow that appears as low signal intensity on T1-weighted images and high signal intensity on T2-weighted images in MRI. It is commonly seen in patients with temporomandibular joint osteoarthritis. Studies have shown that BME is closely related to joint pain, disc displacement and bony degeneration, but its specific mechanism is not yet fully understood, potentially involving abnormal mechanical loading, inflammatory responses and imbalances in bone metabolism. Although BME is considered an early sign of osteoarthritis, BME persists in approximately 71.4% of patients after pain resolution , suggesting the complexity of its association with clinical symptoms. In recent years, advanced MRI techniques (such as T2 mapping and fat suppression sequences) have improved the detection rate of BME and facilitated the assessment of its dynamic changes. However, the exact role of BME in temporomandibular disorders remains controversial. This article reviews the etiology and mechanism, pathology, imaging characteristics, and correlation with clinical symptoms of BME in the temporomandibular joint, and proposing future research directions to to elucidate its significance in disease progression and to provide guidance for clinical diagnosis and treatment.

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来源期刊
中华口腔医学杂志
中华口腔医学杂志 Medicine-Medicine (all)
CiteScore
0.90
自引率
0.00%
发文量
9692
期刊介绍: Founded in August 1953, Chinese Journal of Stomatology is a monthly academic journal of stomatology published publicly at home and abroad, sponsored by the Chinese Medical Association and co-sponsored by the Chinese Stomatology Association. It mainly reports the leading scientific research results and clinical diagnosis and treatment experience in the field of oral medicine, as well as the basic theoretical research that has a guiding role in oral clinical practice and is closely combined with oral clinical practice. Chinese Journal of Over the years, Stomatology has been published in Medline, Scopus database, Toxicology Abstracts Database, Chemical Abstracts Database, American Cancer database, Russian Abstracts database, China Core Journal of Science and Technology, Peking University Core Journal, CSCD and other more than 20 important journals at home and abroad Physical medicine database and retrieval system included.
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