皮埃尔·蒂奥莱（Pierre Tiollais, 1934-2024），终身致力于乙肝病毒研究的基因工程先驱。

IF 0.6 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

M S-medecine Sciences Pub Date : 2025-06-01 Epub Date: 2025-07-07 DOI:10.1051/medsci/2025079

Christian Bréchot, Patrick Charnay, Hugues de Thé, Anne Dejean, Marie-Louise Michel, Pascal Pineau, Pierre Sonigo, Simon Wain-Hobson, Yu Wei, Jean Weissenbach

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引用次数: 0

摘要

法国内科生物学家皮埃尔·蒂奥莱（Pierre Tiollais）于2024年8月5日去世，享年89岁。他因克隆和测序乙型肝炎病毒（HBV）基因组以及开发首批重组HBV疫苗之一而闻名。Pierre Tiollais是巴斯德研究所和巴黎第七大学（现为巴黎cit大学）的教授，他在分子生物学和基因工程在医学研究中的应用方面发挥了关键作用，特别是在对抗乙型肝炎病毒和人类免疫缺陷病毒（艾滋病毒）方面。他的工作通过疫苗接种运动帮助挽救了数百万人的生命。皮埃尔·蒂奥莱也因其对科学界的仁慈指导和承诺而闻名。

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[Pierre Tiollais (1934-2024), a pioneer in genetic engineering with a lifelong commitment to the hepatitis B virus].

Pierre Tiollais, a French physician-biologist, died on August 5, 2024, at 89. He is celebrated for cloning and sequencing the hepatitis B virus (HBV) genome and developing one of the first recombinant HBV vaccines. Professor at the Pasteur Institute and the University Paris VII (now University Paris Cité), Pierre Tiollais has played a key role in the application of molecular biology and genetic engineering in medical research, notably in the fight against HBV and human immunodeficiency virus (HIV). His work has helped saving millions of lives through vaccination campaigns. Pierre Tiollais was also renowned for his benevolent mentorship and commitment to the scientific community.

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来源期刊

M S-medecine Sciences 医学-医学：研究与实验

CiteScore

0.80

自引率

14.30%

发文量

182

审稿时长

4-8 weeks

期刊介绍： m/s offers high-quality review articles in French, covering all areas of biomedical and health research, in a monthly magazine format (10 issues / year). m/s is read by the whole French-speaking community, in France but also in Belgium, Switzerland, Canada, Morocco, Algeria, Tunisia etc. m/s is not a primary publication, and thus will not consider unpublished data. Most articles are invited by the Editors, but spontaneous proposals are welcomed. Each issue combines news and views on the most recent scientific publications, as well as broadly accessible and updated review articles on a specific topic, and essays on science and society, history of science, public health, or reactions to published articles. Each year, m/s also publishes one or two thematic issues focused on a research topic of high interest. All review articles and essays are peer-reviewed.