临床肺炎克雷伯菌分离株中粘菌素耐药性的流行：一项系统综述和荟萃分析。

IF 2.5 4区生物学 Q3 MICROBIOLOGY

Future microbiology Pub Date : 2025-07-06 DOI:10.1080/17460913.2025.2527534

Negar Narimisa, Shirin Bavari, Forough Goodarzi, Amin Khoshbayan

{"title":"临床肺炎克雷伯菌分离株中粘菌素耐药性的流行：一项系统综述和荟萃分析。","authors":"Negar Narimisa, Shirin Bavari, Forough Goodarzi, Amin Khoshbayan","doi":"10.1080/17460913.2025.2527534","DOIUrl":null,"url":null,"abstract":"Objective: Klebsiella pneumoniae commonly causes nosocomial infections, and the rise of colistin-resistant strains poses a significant challenge to public health. This research aims to assess the worldwide prevalence of colistin resistance in K. pneumoniae isolates through a systematic review of scientific literature.Methods: We conducted a systematic literature review of relevant studies available in the PubMed, Scopus, and Web of Science databases up to December 2023. Following this, a meta-analysis was performed using Stata software to determine the overall prevalence of colistin resistance in K. pneumoniae isolates and to conduct subgroup analyses.Results: This meta-analysis reviewed 682 studies and found a global prevalence of colistin resistance at 13% among all K. pneumoniae isolates. Notably, the data shows an increase in colistin resistance from 6% in 2010 to 18% in 2023.Conclusion: This study presents evidence of a substantial global prevalence of colistin resistance among clinical isolates of K. pneumoniae. It is recommended to conduct regular surveillance and testing for colistin resistance to effectively monitor and address this public health issue.","PeriodicalId":12773,"journal":{"name":"Future microbiology","volume":" ","pages":"1-10"},"PeriodicalIF":2.5000,"publicationDate":"2025-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prevalence of colistin resistance in clinical Klebsiella pneumoniae isolates: a systematic review and meta-analysis.\",\"authors\":\"Negar Narimisa, Shirin Bavari, Forough Goodarzi, Amin Khoshbayan\",\"doi\":\"10.1080/17460913.2025.2527534\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: Klebsiella pneumoniae commonly causes nosocomial infections, and the rise of colistin-resistant strains poses a significant challenge to public health. This research aims to assess the worldwide prevalence of colistin resistance in K. pneumoniae isolates through a systematic review of scientific literature.Methods: We conducted a systematic literature review of relevant studies available in the PubMed, Scopus, and Web of Science databases up to December 2023. Following this, a meta-analysis was performed using Stata software to determine the overall prevalence of colistin resistance in K. pneumoniae isolates and to conduct subgroup analyses.Results: This meta-analysis reviewed 682 studies and found a global prevalence of colistin resistance at 13% among all K. pneumoniae isolates. Notably, the data shows an increase in colistin resistance from 6% in 2010 to 18% in 2023.Conclusion: This study presents evidence of a substantial global prevalence of colistin resistance among clinical isolates of K. pneumoniae. It is recommended to conduct regular surveillance and testing for colistin resistance to effectively monitor and address this public health issue.\",\"PeriodicalId\":12773,\"journal\":{\"name\":\"Future microbiology\",\"volume\":\" \",\"pages\":\"1-10\"},\"PeriodicalIF\":2.5000,\"publicationDate\":\"2025-07-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Future microbiology\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1080/17460913.2025.2527534\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Future microbiology","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1080/17460913.2025.2527534","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MICROBIOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

目的：肺炎克雷伯菌通常引起医院感染，耐粘菌素菌株的增加对公共卫生构成了重大挑战。本研究旨在通过对科学文献的系统回顾，评估全球范围内肺炎克雷伯菌分离株粘菌素耐药性的流行情况。方法：我们对PubMed、Scopus和Web of Science数据库中截至2023年12月的相关研究进行了系统的文献综述。随后，使用Stata软件进行荟萃分析，以确定肺炎克雷伯菌分离株中粘菌素耐药性的总体流行情况，并进行亚组分析。结果：这项荟萃分析回顾了682项研究，发现在所有肺炎克雷伯菌分离株中，粘菌素耐药性的全球患病率为13%。值得注意的是，数据显示粘菌素耐药性从2010年的6%增加到2023年的18%。结论：这项研究提供了肺炎克雷伯菌临床分离株中粘菌素耐药的大量全球流行的证据。建议对粘菌素耐药性进行定期监测和检测，以有效监测和解决这一公共卫生问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Prevalence of colistin resistance in clinical Klebsiella pneumoniae isolates: a systematic review and meta-analysis.

Objective: Klebsiella pneumoniae commonly causes nosocomial infections, and the rise of colistin-resistant strains poses a significant challenge to public health. This research aims to assess the worldwide prevalence of colistin resistance in K. pneumoniae isolates through a systematic review of scientific literature.

Methods: We conducted a systematic literature review of relevant studies available in the PubMed, Scopus, and Web of Science databases up to December 2023. Following this, a meta-analysis was performed using Stata software to determine the overall prevalence of colistin resistance in K. pneumoniae isolates and to conduct subgroup analyses.

Results: This meta-analysis reviewed 682 studies and found a global prevalence of colistin resistance at 13% among all K. pneumoniae isolates. Notably, the data shows an increase in colistin resistance from 6% in 2010 to 18% in 2023.

Conclusion: This study presents evidence of a substantial global prevalence of colistin resistance among clinical isolates of K. pneumoniae. It is recommended to conduct regular surveillance and testing for colistin resistance to effectively monitor and address this public health issue.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Future microbiology 生物-微生物学

CiteScore

4.90

自引率

3.20%

发文量

134

审稿时长

6-12 weeks

期刊介绍： Future Microbiology delivers essential information in concise, at-a-glance article formats. Key advances in the field are reported and analyzed by international experts, providing an authoritative but accessible forum for this increasingly important and vast area of research.