心血管风险分层的演变。

IF 0.7 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS
Andrea Matteucci, Stefania Angela Di Fusco, Alessandro Aiello, Silvio Fedele, Stefano Aquilani, Federico Nardi, Furio Colivicchi
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引用次数: 0

摘要

心血管风险分层是预防和管理动脉粥样硬化性疾病的基石。近年来,风险评估模型发生了深刻的转变,从静态和统一的方法转向动态、综合和日益个性化的范式。SCORE2、SCORE2- op、SCORE2- diabetes和SMART2工具通过纳入临床和人口统计学变量(如年龄、合并症、代谢谱和地理环境),可以更准确、更具体地估计绝对心血管风险。同时,使用先进的非侵入性成像技术,如冠状动脉钙评分和颈动脉内膜-中膜厚度等参数,以及生物标志物,已经能够早期识别表面上健康的个体,但实际上存在潜在的风险。这一转变也挑战了一级和二级预防的传统二分法,有利于更连续和更细致的风险分层概念。临床、仪器和生物学数据的整合现在允许更精确和及时的风险评估,为更早、更有针对性和更密集的预防战略铺平道路,旨在减少心血管事件的发生率并显着改善长期预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Evolution of cardiovascular risk stratification].

Cardiovascular risk stratification represents a cornerstone in preventing and managing atherosclerotic diseases. There has been a profound transformation in risk assessment models in recent years, shifting from static and uniform approaches to dynamic, integrated, and increasingly personalized paradigms. The SCORE2, SCORE2-OP, SCORE2-Diabetes and SMART2 tools allow for a more accurate and context-specific estimation of absolute cardiovascular risk by incorporating clinical and demographic variables such as age, comorbidities, metabolic profile, and geographic context. In parallel, the use of advanced non-invasive imaging techniques, parameters such as coronary artery calcium scoring and carotid intima-media thickness, as well as biomarkers, has enabled the early identification of apparently healthy individuals who are at hidden risk. This shift also challenges the traditional dichotomy of primary and secondary prevention, favoring a more continuous and nuanced concept of risk stratification. The integration of clinical, instrumental, and biological data now allows for more refined and timely risk assessment, paving the way for earlier, more targeted, and intensive preventive strategies aimed at reducing the incidence of cardiovascular events and significantly improving long-term outcomes.

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Giornale italiano di cardiologia
Giornale italiano di cardiologia CARDIAC & CARDIOVASCULAR SYSTEMS-
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