Inside Front Cover: Hierarchically Self-Assembled Anion-Coordination-Driven Gels for Guest Segregation and Electrical Sensing (Angew. Chem. 28/2025)

The phase separation of self-assembled hosts in a gel from liquid guests is a convenient approach for heterogeneous encapsulation. In their Communication (e202504207), Dong Yang and co-workers report a class of gels formed through hierarchical self-assembly of “aniono” helicates, which can be utilized as filling material in columns and show the ability to selectively encapsulate and release choline. This study introduces the concept of flowing a solution containing guests through a host-containing gel for effective guest separation. The process of guest binding could be also monitored in real time via electrical characterization.