系统性红斑狼疮期间的心电图和超声心动图异常：喀麦隆患者的第一个数据

IF 0.3 Q4 Medicine

Annales de cardiologie et d'angeiologie Pub Date : 2025-07-08 DOI:10.1016/j.ancard.2025.101905

Jan René Nkeck , Valérie Ndobo-Koe , Stela Valdesse Kamgue Wambo , Carelle Doen Guedi , Adeline Pelda , Gisèle Flora Nandjip , Baudelaire Fojo , Caroline Ngoufack-Tientcheu , Blondelle Ndifon , Laeticia Yowo , Liliane Kuate Mfeukeu , Madeleine Ngandeu Singwé

{"title":"系统性红斑狼疮期间的心电图和超声心动图异常：喀麦隆患者的第一个数据","authors":"Jan René Nkeck , Valérie Ndobo-Koe , Stela Valdesse Kamgue Wambo , Carelle Doen Guedi , Adeline Pelda , Gisèle Flora Nandjip , Baudelaire Fojo , Caroline Ngoufack-Tientcheu , Blondelle Ndifon , Laeticia Yowo , Liliane Kuate Mfeukeu , Madeleine Ngandeu Singwé","doi":"10.1016/j.ancard.2025.101905","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>Limited data are available on cardiac manifestations in systemic lupus erythematosus (SLE) in Cameroon. The aim of this study was to report on electrocardiographic and echocardiographic abnormalities in this population.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted from October 2023 to May 2024 at the Yaoundé Central Hospital, involving patients followed up for SLE satisfying the ACR/EULAR 2019 criteria, paired with healthy subjects. They underwent electrocardiographic and echocardiographic examinations. Frequencies of abnormalities were compared using Fisher's exact test. The significance threshold was 0.05.</div></div><div><h3>Results</h3><div>We included 55 SLE patients (94.5% female) with a mean age of 39 (10) years, and 55 matched control subjects. Clinically, 10 (18.2%) SLE patients presented with functional cardiac signs. Electrocardiographic and echographic abnormalities accounted for 29.1% and 43.6% of patients, respectively, with frequencies significantly higher than those of controls (10.9% and 7.3%, respectively). These included sinus tachycardia (14.5%), ST elevation (14.5%), and T-wave inversion (16.3%) on electrocardiography; pericardial effusion (25.5%), mitral insufficiency (23.6%), aortic insufficiency (20%), and pulmonary hypertension (14.5%) on echocardiography.</div></div><div><h3>Conclusion</h3><div>Electrocardiographic and echocardiographic abnormalities are common, affecting one-third and two-fifths respectively of SLE patients in our sample. They are usually asymptomatic, calling for screening and follow-up, as some can have a long-term prognostic impact.</div></div>","PeriodicalId":7899,"journal":{"name":"Annales de cardiologie et d'angeiologie","volume":"74 6","pages":"Article 101905"},"PeriodicalIF":0.3000,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Anomalies électrocardiographiques et échocardiographiques au cours du lupus érythémateux systémique : les premières données des patients Camerounais\",\"authors\":\"Jan René Nkeck , Valérie Ndobo-Koe , Stela Valdesse Kamgue Wambo , Carelle Doen Guedi , Adeline Pelda , Gisèle Flora Nandjip , Baudelaire Fojo , Caroline Ngoufack-Tientcheu , Blondelle Ndifon , Laeticia Yowo , Liliane Kuate Mfeukeu , Madeleine Ngandeu Singwé\",\"doi\":\"10.1016/j.ancard.2025.101905\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><div>Limited data are available on cardiac manifestations in systemic lupus erythematosus (SLE) in Cameroon. The aim of this study was to report on electrocardiographic and echocardiographic abnormalities in this population.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted from October 2023 to May 2024 at the Yaoundé Central Hospital, involving patients followed up for SLE satisfying the ACR/EULAR 2019 criteria, paired with healthy subjects. They underwent electrocardiographic and echocardiographic examinations. Frequencies of abnormalities were compared using Fisher's exact test. The significance threshold was 0.05.</div></div><div><h3>Results</h3><div>We included 55 SLE patients (94.5% female) with a mean age of 39 (10) years, and 55 matched control subjects. Clinically, 10 (18.2%) SLE patients presented with functional cardiac signs. Electrocardiographic and echographic abnormalities accounted for 29.1% and 43.6% of patients, respectively, with frequencies significantly higher than those of controls (10.9% and 7.3%, respectively). These included sinus tachycardia (14.5%), ST elevation (14.5%), and T-wave inversion (16.3%) on electrocardiography; pericardial effusion (25.5%), mitral insufficiency (23.6%), aortic insufficiency (20%), and pulmonary hypertension (14.5%) on echocardiography.</div></div><div><h3>Conclusion</h3><div>Electrocardiographic and echocardiographic abnormalities are common, affecting one-third and two-fifths respectively of SLE patients in our sample. They are usually asymptomatic, calling for screening and follow-up, as some can have a long-term prognostic impact.</div></div>\",\"PeriodicalId\":7899,\"journal\":{\"name\":\"Annales de cardiologie et d'angeiologie\",\"volume\":\"74 6\",\"pages\":\"Article 101905\"},\"PeriodicalIF\":0.3000,\"publicationDate\":\"2025-07-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annales de cardiologie et d'angeiologie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0003392825000447\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annales de cardiologie et d'angeiologie","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0003392825000447","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

摘要

喀麦隆系统性红斑狼疮（SLE）患者的心脏表现数据有限。本研究的目的是报告这一人群的心电图和超声心动图异常。方法于2023年10月至2024年5月在雅温得中心医院进行了一项横断面研究，纳入了满足ACR/EULAR 2019标准的SLE患者，与健康受试者配对。他们接受了心电图和超声心动图检查。使用Fisher精确检验比较异常频率。显著性阈值为0.05。结果我们纳入55例SLE患者（94.5%为女性），平均年龄39（10）岁，以及55名匹配的对照组。临床有10例（18.2%）SLE患者出现功能性心脏征象。心电图和超声异常分别占29.1%和43.6%，频率明显高于对照组（分别为10.9%和7.3%）。包括窦性心动过速（14.5%）、ST段抬高（14.5%）和t波倒置（16.3%）；超声心动图显示心包积液（25.5%）、二尖瓣不全（23.6%）、主动脉不全（20%）和肺动脉高压（14.5%）。结论心电图和超声心动图异常是常见的，分别影响我们样本中三分之一和五分之二的SLE患者。它们通常是无症状的，需要进行筛查和随访，因为有些可能会对预后产生长期影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Anomalies électrocardiographiques et échocardiographiques au cours du lupus érythémateux systémique : les premières données des patients Camerounais

Introduction

Limited data are available on cardiac manifestations in systemic lupus erythematosus (SLE) in Cameroon. The aim of this study was to report on electrocardiographic and echocardiographic abnormalities in this population.

Methods

A cross-sectional study was conducted from October 2023 to May 2024 at the Yaoundé Central Hospital, involving patients followed up for SLE satisfying the ACR/EULAR 2019 criteria, paired with healthy subjects. They underwent electrocardiographic and echocardiographic examinations. Frequencies of abnormalities were compared using Fisher's exact test. The significance threshold was 0.05.

Results

We included 55 SLE patients (94.5% female) with a mean age of 39 (10) years, and 55 matched control subjects. Clinically, 10 (18.2%) SLE patients presented with functional cardiac signs. Electrocardiographic and echographic abnormalities accounted for 29.1% and 43.6% of patients, respectively, with frequencies significantly higher than those of controls (10.9% and 7.3%, respectively). These included sinus tachycardia (14.5%), ST elevation (14.5%), and T-wave inversion (16.3%) on electrocardiography; pericardial effusion (25.5%), mitral insufficiency (23.6%), aortic insufficiency (20%), and pulmonary hypertension (14.5%) on echocardiography.

Conclusion

Electrocardiographic and echocardiographic abnormalities are common, affecting one-third and two-fifths respectively of SLE patients in our sample. They are usually asymptomatic, calling for screening and follow-up, as some can have a long-term prognostic impact.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Annales de cardiologie et d'angeiologie 医学-外周血管病

CiteScore

0.60

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Organe scientifique de référence fondé en 1951, les Annales de cardiologie et d''angéiologie abordent tous les domaines qui intéressent quotidiennement les cardiologues et les angéiologues praticiens : neurologie et radiologie vasculaires, hémostase, diabétologie, médecine interne, épidémiologie et prévention. Les Annales de cardiologie et d''angéiologie sont indexées aux grandes bases de données et publient rapidement, et en conformité avec les normes internationales de publication scientifique, des articles en français sur la pathologie cardiaque.