Nidia del Carmen Quintal Bojórquez , Maira Rubi Segura Campos
{"title":"探讨抗肥胖肽在癌症预防中的治疗潜力","authors":"Nidia del Carmen Quintal Bojórquez , Maira Rubi Segura Campos","doi":"10.1016/j.prenap.2025.100294","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>Overweight and obesity are significant risk factors for cancer development, accounting for approximately 20 % of all cancer cases. Numerous studies have highlighted the potential of bioactive peptides derived from functional foods in preventing and treating noncommunicable diseases such as obesity and cancer. This study aims to analyze the role of bioactive peptides in preventing and treating obesity and the consequent reduction in cancer risk.</div></div><div><h3>Methods</h3><div>Data were collected from peer-reviewed journals and statistical information regarding cancer and obesity was sourced from relevant Global Observatories.</div></div><div><h3>Findings</h3><div>Reducing obesity and overweight significantly lowers the risk of cancer. Bioactive peptides have emerged as a promising therapeutic strategy, offering benefits without the adverse effects of conventional drugs. These peptides act mainly by modulating lipid metabolism, inflammation, adipogenesis, and digestive enzymes linked to obesity progression.</div></div><div><h3>Conclusion</h3><div>The ongoing research into bioactive peptides should motivate increased investment and research efforts towards developing effective anti-obesity therapies, which, in turn, may contribute to cancer prevention.</div></div>","PeriodicalId":101014,"journal":{"name":"Pharmacological Research - Natural Products","volume":"8 ","pages":"Article 100294"},"PeriodicalIF":0.0000,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Exploring the therapeutic potential of anti-obesity peptides in cancer prevention\",\"authors\":\"Nidia del Carmen Quintal Bojórquez , Maira Rubi Segura Campos\",\"doi\":\"10.1016/j.prenap.2025.100294\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><div>Overweight and obesity are significant risk factors for cancer development, accounting for approximately 20 % of all cancer cases. Numerous studies have highlighted the potential of bioactive peptides derived from functional foods in preventing and treating noncommunicable diseases such as obesity and cancer. This study aims to analyze the role of bioactive peptides in preventing and treating obesity and the consequent reduction in cancer risk.</div></div><div><h3>Methods</h3><div>Data were collected from peer-reviewed journals and statistical information regarding cancer and obesity was sourced from relevant Global Observatories.</div></div><div><h3>Findings</h3><div>Reducing obesity and overweight significantly lowers the risk of cancer. Bioactive peptides have emerged as a promising therapeutic strategy, offering benefits without the adverse effects of conventional drugs. These peptides act mainly by modulating lipid metabolism, inflammation, adipogenesis, and digestive enzymes linked to obesity progression.</div></div><div><h3>Conclusion</h3><div>The ongoing research into bioactive peptides should motivate increased investment and research efforts towards developing effective anti-obesity therapies, which, in turn, may contribute to cancer prevention.</div></div>\",\"PeriodicalId\":101014,\"journal\":{\"name\":\"Pharmacological Research - Natural Products\",\"volume\":\"8 \",\"pages\":\"Article 100294\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-07-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pharmacological Research - Natural Products\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2950199725001545\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmacological Research - Natural Products","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2950199725001545","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Exploring the therapeutic potential of anti-obesity peptides in cancer prevention
Introduction
Overweight and obesity are significant risk factors for cancer development, accounting for approximately 20 % of all cancer cases. Numerous studies have highlighted the potential of bioactive peptides derived from functional foods in preventing and treating noncommunicable diseases such as obesity and cancer. This study aims to analyze the role of bioactive peptides in preventing and treating obesity and the consequent reduction in cancer risk.
Methods
Data were collected from peer-reviewed journals and statistical information regarding cancer and obesity was sourced from relevant Global Observatories.
Findings
Reducing obesity and overweight significantly lowers the risk of cancer. Bioactive peptides have emerged as a promising therapeutic strategy, offering benefits without the adverse effects of conventional drugs. These peptides act mainly by modulating lipid metabolism, inflammation, adipogenesis, and digestive enzymes linked to obesity progression.
Conclusion
The ongoing research into bioactive peptides should motivate increased investment and research efforts towards developing effective anti-obesity therapies, which, in turn, may contribute to cancer prevention.