体力活动和睡眠时间与全因和特定原因死亡率的联合关系：一项对153,866名墨西哥成年人的前瞻性研究

IF 3.6 2区医学 Q2 GERIATRICS & GERONTOLOGY

Maturitas Pub Date : 2025-07-03 DOI:10.1016/j.maturitas.2025.108656

Weder Alves da Silva , Diego Christofaro , Pablo del Val Martín , Adilson Marques , Miguel Peralta , Carlos Cristi-Montero , Leandro F.M. Rezende , Gaspar Chiappa , Gerson Ferrari

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引用次数: 0

摘要

目的研究体力活动（每周频率和持续时间）和睡眠时间与全因死亡率和特定原因死亡率的联合关系。方法我们对来自墨西哥城前瞻性研究的153,866名参与者进行了前瞻性队列研究。Cox比例风险回归用于估计频率(none, <；1、1 - 2和≥3次/周)和疗程(无，<；30,30 - 60和≥60分钟/天)的身体活动和睡眠时间(建议：7-9小时/天；低于/高于建议：<；7或>；9小时/天)，有全因和特定原因死亡的风险（心血管疾病、癌症和呼吸系统疾病）。结果在15.6年的随访中，观察到在没有身体活动和推荐睡眠时间的参与者中，全因疾病、心血管疾病和癌症死亡率的风险更高；& lt;1次/周的体力活动和低于/高于推荐睡眠时间；没有体育活动和低于/高于推荐睡眠时间（与高体育活动和推荐睡眠时间相比）。在考虑体力活动持续时间时，也观察到类似的正相关。全因、心血管疾病和癌症死亡率的风险最高的是没有身体活动（持续时间）和低于/高于建议睡眠时间的参与者。结论：研究结果表明，低水平的身体活动和不推荐的睡眠时间共同增加了全因和特定原因死亡的风险。

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Joint association of physical activity and sleep duration with all-cause and cause-specific mortality: A prospective study of 153,866 Mexican adults

Objective

This study investigated the joint association of physical activity (weekly frequency and duration) and sleep duration with all-cause and cause-specific mortality.

Methods

We conducted a prospective cohort study of 153,866 participants from the Mexico City Prospective Study. Cox proportional hazards regression was used to estimate the joint associations of frequency (none, < 1, 1–2, and ≥ 3 times/week) and session duration (none, < 30, 30–60, and ≥ 60 min/day) of physical activity and sleep duration (recommended: 7–9 h/day; below/above recommended: <7 or > 9 h/day) with the risk of all-cause and cause-specific mortality (cardiovascular disease, cancer, and respiratory diseases).

Results

Over 15.6 years of follow-up, higher risks of all-cause, cardiovascular diseases, and cancer mortality were observed among participants with: no physical activity and recommended sleep duration; < 1 time/week of physical activity and below/above recommended sleep; and no physical activity and below/above recommended sleep (compared to higher physical activity and recommended sleep duration. Similar positive associations were observed when considering physical activity duration. The highest risks of all-cause, cardiovascular disease, and cancer mortality were found among participants with no physical activity (duration) and below/above recommended sleep duration.

Conclusions

Our findings suggest that low levels of physical activity and non-recommended sleep durations jointly increase the risk of all-cause and cause-specific mortality.

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来源期刊

Maturitas 医学-妇产科学

CiteScore

9.10

自引率

2.00%

发文量

142

审稿时长

40 days

期刊介绍： Maturitas is an international multidisciplinary peer reviewed scientific journal of midlife health and beyond publishing original research, reviews, consensus statements and guidelines, and mini-reviews. The journal provides a forum for all aspects of postreproductive health in both genders ranging from basic science to health and social care. Topic areas include:• Aging• Alternative and Complementary medicines• Arthritis and Bone Health• Cancer• Cardiovascular Health• Cognitive and Physical Functioning• Epidemiology, health and social care• Gynecology/ Reproductive Endocrinology• Nutrition/ Obesity Diabetes/ Metabolic Syndrome• Menopause, Ovarian Aging• Mental Health• Pharmacology• Sexuality• Quality of Life