{"title":"发展本土拟人化异质女性盆腔幻象用于放射治疗中心剂量学审计。","authors":"Ajay Katake, Lalit Kumar, Balbir Singh, Kruti Haraniya, Rajesh Vashistha, Deepak Basandrai","doi":"10.4103/jcrt.jcrt_1816_24","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>The aim of the present study was to create an indigenous anthropomorphic heterogeneous female pelvis (AHFP) phantom for quality assurance and dosimetric audits in advance radiotherapy centers.</p><p><strong>Material and methods: </strong>The AHFP phantom was designed using paraffin wax, epoxy, water, polyvinyl chloride (PVC), and a hardener. A dosimetric audit was conducted using the fabricated phantom among four different hospitals. The hospitals were instructed to perform the procedure of treatment planning and delivery as per their institutional protocol. Each institute was asked to make optimized plans using available intensity-modulated radiation therapy (IMRT) and rapid arc (RA) delivery technique. Apart from this, additional plans were generated for using single field (1F), double field (2F), three field (3F), and four field (4F) for 5 cm × 5 cm and 10 cm × 10 cm geometry, 3dimensional conformal radiotherapy (3F, 4F), and IMRT (5F, 7F and 9F).</p><p><strong>Results: </strong>With regard to the measured radiological properties, the mean Hounsfield units (HUs) were 87.3 ± 39.45, 1122.5 ± 270.1, 1312.2 ± 232.5, 10.1 ± 58.5, and 20.2 ± 33.8; the mean relative electron densities (REDs) were 1.087 ± 0.04, 1.673 ± 0.16, 1.765 ± 0.14, 1.010 ± 0.06, and 1.021 ± 0.03 g/cc and the mean mass densities (MDs) were 1.074 ± 0.03, 1.673 ± 0.15, 1.765 ± 0.16, 1.011 ± 0.06, and 1.021 ± 0.03 g/cc for soft tissue, femoral head, bones, rectum, and bladder of AHFP phantom, respectively. The percentage deviations between measured and computed doses were within ± 3% for all measurements performed under the study in each hospital.</p><p><strong>Conclusion: </strong>The fabricated AHFP phantom mimics the size, shape, and radiological properties of female pelvis. The dosimetric results from participant hospitals were within prescribed tolerance. The present study confirms the efficacy of the AHFP phantom as a trustworthy quality assurance tool in radiotherapy. Hence, it can be used for end-to-end validation and dosimetric audit of advanced radiation therapy centers.</p>","PeriodicalId":94070,"journal":{"name":"Journal of cancer research and therapeutics","volume":"21 3","pages":"678-685"},"PeriodicalIF":1.3000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Developing an indigenous anthropomorphic heterogeneous female pelvic phantom for dosimetric audit in radiotherapy centers.\",\"authors\":\"Ajay Katake, Lalit Kumar, Balbir Singh, Kruti Haraniya, Rajesh Vashistha, Deepak Basandrai\",\"doi\":\"10.4103/jcrt.jcrt_1816_24\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aim: </strong>The aim of the present study was to create an indigenous anthropomorphic heterogeneous female pelvis (AHFP) phantom for quality assurance and dosimetric audits in advance radiotherapy centers.</p><p><strong>Material and methods: </strong>The AHFP phantom was designed using paraffin wax, epoxy, water, polyvinyl chloride (PVC), and a hardener. A dosimetric audit was conducted using the fabricated phantom among four different hospitals. The hospitals were instructed to perform the procedure of treatment planning and delivery as per their institutional protocol. Each institute was asked to make optimized plans using available intensity-modulated radiation therapy (IMRT) and rapid arc (RA) delivery technique. Apart from this, additional plans were generated for using single field (1F), double field (2F), three field (3F), and four field (4F) for 5 cm × 5 cm and 10 cm × 10 cm geometry, 3dimensional conformal radiotherapy (3F, 4F), and IMRT (5F, 7F and 9F).</p><p><strong>Results: </strong>With regard to the measured radiological properties, the mean Hounsfield units (HUs) were 87.3 ± 39.45, 1122.5 ± 270.1, 1312.2 ± 232.5, 10.1 ± 58.5, and 20.2 ± 33.8; the mean relative electron densities (REDs) were 1.087 ± 0.04, 1.673 ± 0.16, 1.765 ± 0.14, 1.010 ± 0.06, and 1.021 ± 0.03 g/cc and the mean mass densities (MDs) were 1.074 ± 0.03, 1.673 ± 0.15, 1.765 ± 0.16, 1.011 ± 0.06, and 1.021 ± 0.03 g/cc for soft tissue, femoral head, bones, rectum, and bladder of AHFP phantom, respectively. The percentage deviations between measured and computed doses were within ± 3% for all measurements performed under the study in each hospital.</p><p><strong>Conclusion: </strong>The fabricated AHFP phantom mimics the size, shape, and radiological properties of female pelvis. The dosimetric results from participant hospitals were within prescribed tolerance. The present study confirms the efficacy of the AHFP phantom as a trustworthy quality assurance tool in radiotherapy. Hence, it can be used for end-to-end validation and dosimetric audit of advanced radiation therapy centers.</p>\",\"PeriodicalId\":94070,\"journal\":{\"name\":\"Journal of cancer research and therapeutics\",\"volume\":\"21 3\",\"pages\":\"678-685\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of cancer research and therapeutics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/jcrt.jcrt_1816_24\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/7/5 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of cancer research and therapeutics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/jcrt.jcrt_1816_24","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/5 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
目的:本研究的目的是创造一个本土拟人化异质女性骨盆(AHFP)假体,用于放射治疗中心的质量保证和剂量学审计。材料和方法:采用石蜡、环氧树脂、水、聚氯乙烯(PVC)和硬化剂设计AHFP模体。在四家不同的医院中使用捏造的假体进行了剂量学审计。指示医院按照其机构协议执行治疗计划和交付程序。每个研究所被要求使用现有的调强放射治疗(IMRT)和快速弧线(RA)传递技术制定优化的计划。除此之外,还针对5 cm × 5 cm和10 cm × 10 cm几何形状、三维适形放疗(3F、4F)和IMRT (5F、7F和9F)生成了使用单场(1F)、双场(2F)、三场(3F)和四场(4F)的附加方案。结果:所测放射学指标的HUs平均值分别为87.3±39.45、1122.5±270.1、1312.2±232.5、10.1±58.5和20.2±33.8;AHFP幻象软组织、股骨头、骨骼、直肠、膀胱的平均相对电子密度(REDs)分别为1.087±0.04、1.673±0.16、1.765±0.14、1.010±0.06、1.021±0.03 g/cc,平均质量密度(MDs)分别为1.074±0.03、1.673±0.15、1.765±0.16、1.011±0.06、1.021±0.03 g/cc。在每个医院进行的所有测量中,测量剂量与计算剂量之间的百分比偏差在±3%以内。结论:制备的AHFP假体模拟了女性骨盆的大小、形状和放射学特征。来自参与医院的剂量学结果在规定的耐受范围内。本研究证实了AHFP假体作为放射治疗中可靠的质量保证工具的有效性。因此,它可用于先进放射治疗中心的端到端验证和剂量学审计。
Developing an indigenous anthropomorphic heterogeneous female pelvic phantom for dosimetric audit in radiotherapy centers.
Aim: The aim of the present study was to create an indigenous anthropomorphic heterogeneous female pelvis (AHFP) phantom for quality assurance and dosimetric audits in advance radiotherapy centers.
Material and methods: The AHFP phantom was designed using paraffin wax, epoxy, water, polyvinyl chloride (PVC), and a hardener. A dosimetric audit was conducted using the fabricated phantom among four different hospitals. The hospitals were instructed to perform the procedure of treatment planning and delivery as per their institutional protocol. Each institute was asked to make optimized plans using available intensity-modulated radiation therapy (IMRT) and rapid arc (RA) delivery technique. Apart from this, additional plans were generated for using single field (1F), double field (2F), three field (3F), and four field (4F) for 5 cm × 5 cm and 10 cm × 10 cm geometry, 3dimensional conformal radiotherapy (3F, 4F), and IMRT (5F, 7F and 9F).
Results: With regard to the measured radiological properties, the mean Hounsfield units (HUs) were 87.3 ± 39.45, 1122.5 ± 270.1, 1312.2 ± 232.5, 10.1 ± 58.5, and 20.2 ± 33.8; the mean relative electron densities (REDs) were 1.087 ± 0.04, 1.673 ± 0.16, 1.765 ± 0.14, 1.010 ± 0.06, and 1.021 ± 0.03 g/cc and the mean mass densities (MDs) were 1.074 ± 0.03, 1.673 ± 0.15, 1.765 ± 0.16, 1.011 ± 0.06, and 1.021 ± 0.03 g/cc for soft tissue, femoral head, bones, rectum, and bladder of AHFP phantom, respectively. The percentage deviations between measured and computed doses were within ± 3% for all measurements performed under the study in each hospital.
Conclusion: The fabricated AHFP phantom mimics the size, shape, and radiological properties of female pelvis. The dosimetric results from participant hospitals were within prescribed tolerance. The present study confirms the efficacy of the AHFP phantom as a trustworthy quality assurance tool in radiotherapy. Hence, it can be used for end-to-end validation and dosimetric audit of advanced radiation therapy centers.