Nessrin A. Taha BDS, MFDS, GradDipClinDent, DClinDent(Endo), FRACDS, FRACDs (Endo), PhD , Heba B. Jaradat BDS, MClinDent , Alaa DkmaK BDS, MClinDent , Imran Zainal Abidin BDS, MClinDent, MEndo
{"title":"成熟牙伴可逆性牙髓炎的龋髓暴露:直接髓盖和部分髓切开术的随机临床试验。","authors":"Nessrin A. Taha BDS, MFDS, GradDipClinDent, DClinDent(Endo), FRACDS, FRACDs (Endo), PhD , Heba B. Jaradat BDS, MClinDent , Alaa DkmaK BDS, MClinDent , Imran Zainal Abidin BDS, MClinDent, MEndo","doi":"10.1016/j.joen.2025.06.019","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>No clear guidelines exist for the selection of vital pulp therapy procedures in carious pulp exposures. This study aimed to compare the outcomes of direct pulp capping and partial pulpotomy in mature permanent teeth with reversible pulpitis.</div></div><div><h3>Methods</h3><div>The study was a parallel double-blind randomized clinical trial of 140 mature permanent teeth. Teeth were asymptomatic or with symptoms of reversible pulpitis and received direct pulp capping (<em>n</em> = 67) or partial pulpotomy (<em>n</em> = 73). After intraoperative assessment under magnification and hemostasis, NeoPUTTY (Avalon Biomed, Bradenton, FL) was placed as the capping material. Baseline variables were recorded. Patients were scheduled for 6- and 12-month clinical and radiographic follow-up. Results were statistically compared using chi-square tests and regression analysis.</div></div><div><h3>Results</h3><div>Approximately half of the teeth (74/140) were symptomatic, with no significant difference in the preoperative pain levels between the 2 groups (<em>P</em> = .75), both treatments resulted in significant pain reduction after 1 week (<em>P</em> < .001). After 6 months, 4 cases of partial pulpotomy and 10 cases of direct pulp capping failed; the success rate was 94.4% versus 84.4%, <em>P</em> = .057 respectively. At 1 year, 2 additional failures occurred in each treatment group with success rates of 91.5% for partial pulpotomy and 81.3% for direct pulp capping (<em>P</em> = .08). There were no significant prognostic factors for pulp capping or partial pulpotomy, multivariate analysis did not reveal any significant interactions.</div></div><div><h3>Conclusions</h3><div>Carious pulp exposure in teeth with reversible pulpitis can be managed successfully by either direct pulp capping or partial pulpotomy depending on the intraoperative assessment of the exposed pulp.</div></div>","PeriodicalId":15703,"journal":{"name":"Journal of endodontics","volume":"51 10","pages":"Pages 1342-1350"},"PeriodicalIF":3.6000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Carious Pulp Exposure in Mature Teeth With Reversible Pulpitis: A Randomized Clinical Trial of Direct Pulp Capping and Partial Pulpotomy\",\"authors\":\"Nessrin A. Taha BDS, MFDS, GradDipClinDent, DClinDent(Endo), FRACDS, FRACDs (Endo), PhD , Heba B. Jaradat BDS, MClinDent , Alaa DkmaK BDS, MClinDent , Imran Zainal Abidin BDS, MClinDent, MEndo\",\"doi\":\"10.1016/j.joen.2025.06.019\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><div>No clear guidelines exist for the selection of vital pulp therapy procedures in carious pulp exposures. This study aimed to compare the outcomes of direct pulp capping and partial pulpotomy in mature permanent teeth with reversible pulpitis.</div></div><div><h3>Methods</h3><div>The study was a parallel double-blind randomized clinical trial of 140 mature permanent teeth. Teeth were asymptomatic or with symptoms of reversible pulpitis and received direct pulp capping (<em>n</em> = 67) or partial pulpotomy (<em>n</em> = 73). After intraoperative assessment under magnification and hemostasis, NeoPUTTY (Avalon Biomed, Bradenton, FL) was placed as the capping material. Baseline variables were recorded. Patients were scheduled for 6- and 12-month clinical and radiographic follow-up. Results were statistically compared using chi-square tests and regression analysis.</div></div><div><h3>Results</h3><div>Approximately half of the teeth (74/140) were symptomatic, with no significant difference in the preoperative pain levels between the 2 groups (<em>P</em> = .75), both treatments resulted in significant pain reduction after 1 week (<em>P</em> < .001). After 6 months, 4 cases of partial pulpotomy and 10 cases of direct pulp capping failed; the success rate was 94.4% versus 84.4%, <em>P</em> = .057 respectively. At 1 year, 2 additional failures occurred in each treatment group with success rates of 91.5% for partial pulpotomy and 81.3% for direct pulp capping (<em>P</em> = .08). There were no significant prognostic factors for pulp capping or partial pulpotomy, multivariate analysis did not reveal any significant interactions.</div></div><div><h3>Conclusions</h3><div>Carious pulp exposure in teeth with reversible pulpitis can be managed successfully by either direct pulp capping or partial pulpotomy depending on the intraoperative assessment of the exposed pulp.</div></div>\",\"PeriodicalId\":15703,\"journal\":{\"name\":\"Journal of endodontics\",\"volume\":\"51 10\",\"pages\":\"Pages 1342-1350\"},\"PeriodicalIF\":3.6000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of endodontics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0099239925003917\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of endodontics","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0099239925003917","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Carious Pulp Exposure in Mature Teeth With Reversible Pulpitis: A Randomized Clinical Trial of Direct Pulp Capping and Partial Pulpotomy
Introduction
No clear guidelines exist for the selection of vital pulp therapy procedures in carious pulp exposures. This study aimed to compare the outcomes of direct pulp capping and partial pulpotomy in mature permanent teeth with reversible pulpitis.
Methods
The study was a parallel double-blind randomized clinical trial of 140 mature permanent teeth. Teeth were asymptomatic or with symptoms of reversible pulpitis and received direct pulp capping (n = 67) or partial pulpotomy (n = 73). After intraoperative assessment under magnification and hemostasis, NeoPUTTY (Avalon Biomed, Bradenton, FL) was placed as the capping material. Baseline variables were recorded. Patients were scheduled for 6- and 12-month clinical and radiographic follow-up. Results were statistically compared using chi-square tests and regression analysis.
Results
Approximately half of the teeth (74/140) were symptomatic, with no significant difference in the preoperative pain levels between the 2 groups (P = .75), both treatments resulted in significant pain reduction after 1 week (P < .001). After 6 months, 4 cases of partial pulpotomy and 10 cases of direct pulp capping failed; the success rate was 94.4% versus 84.4%, P = .057 respectively. At 1 year, 2 additional failures occurred in each treatment group with success rates of 91.5% for partial pulpotomy and 81.3% for direct pulp capping (P = .08). There were no significant prognostic factors for pulp capping or partial pulpotomy, multivariate analysis did not reveal any significant interactions.
Conclusions
Carious pulp exposure in teeth with reversible pulpitis can be managed successfully by either direct pulp capping or partial pulpotomy depending on the intraoperative assessment of the exposed pulp.
期刊介绍:
The Journal of Endodontics, the official journal of the American Association of Endodontists, publishes scientific articles, case reports and comparison studies evaluating materials and methods of pulp conservation and endodontic treatment. Endodontists and general dentists can learn about new concepts in root canal treatment and the latest advances in techniques and instrumentation in the one journal that helps them keep pace with rapid changes in this field.