植物和微藻制成的鱼类疫苗。

IF 4.1 2区农林科学 Q1 FISHERIES

Fish & shellfish immunology Pub Date : 2025-07-02 DOI:10.1016/j.fsi.2025.110539

Carlos Angulo , Martha Reyes-Becerril , Bernardo Bañuelos-Hernández , Abel Ramos-Vega , Edgar Trujillo , Miriam Angulo , Alejandra Cisneros-Geraldo , Elizabeth Monreal-Escalante

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引用次数: 0

摘要

水产养殖是增长最快的食品部门之一，为可持续生产解决了疾病问题。对“水生”疫苗的需求是不可避免的。几十年来，植物和微藻一直被开发为陆生动物和人类负担得起的疫苗生产和口服平台。这些系统的最新进展集中在为水产养殖生产疫苗，并取得了有希望的成果。本文讨论了这两种技术，描述了有效疫苗生产的策略和工程工具的工作流程，提供了接种疫苗的基本鱼类免疫学考虑因素，并检查了已开发的植物和微藻制备的鱼类疫苗。指出了障碍，提出了克服这些障碍的建议战略，以及工业采用的前景。

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Plant- and microalgae-made fish vaccines

Fish aquaculture is one of the fastest-growing food sectors, fencing disease problems for sustainable production. The need for “aquatic” vaccines has been inevitable. Plants and microalgae have been developed for decades as affordable vaccine production and oral delivery platforms for terrestrial animals and human beings. Recent advances in these systems have focused on producing vaccines for aquaculture with promising outcomes. This review discusses both technologies, describing a workflow with strategies and engineering tools available for efficient vaccine production, providing basic fish immunology considerations for vaccination, and examining the developed plant- and microalgae-made vaccines for fish. Obstacles are identified, and proposed strategies are provided to overcome them, along with prospects for industrial adoption.

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来源期刊

Fish & shellfish immunology 农林科学-海洋与淡水生物学

CiteScore

7.50

自引率

19.10%

发文量

750

审稿时长

68 days

期刊介绍： Fish and Shellfish Immunology rapidly publishes high-quality, peer-refereed contributions in the expanding fields of fish and shellfish immunology. It presents studies on the basic mechanisms of both the specific and non-specific defense systems, the cells, tissues, and humoral factors involved, their dependence on environmental and intrinsic factors, response to pathogens, response to vaccination, and applied studies on the development of specific vaccines for use in the aquaculture industry.