小儿人群中的胆道运动障碍

IF 1.4 3区 医学 Q3 PEDIATRICS
Sophia MV Schermerhorn , Afif N. Kulaylat , Donald J. Lucas
{"title":"小儿人群中的胆道运动障碍","authors":"Sophia MV Schermerhorn ,&nbsp;Afif N. Kulaylat ,&nbsp;Donald J. Lucas","doi":"10.1016/j.sempedsurg.2025.151503","DOIUrl":null,"url":null,"abstract":"<div><div>Biliary dyskinesia (BD) is a functional gallbladder disorder increasingly diagnosed in pediatric patients and a leading indication for laparoscopic cholecystectomy (LC). The pathophysiology remains unclear despite its prevalence, with gallbladder dysmotility and inflammation implicated. Diagnostic challenges arise from a lack of validated pediatric criteria and inconsistent hepatobiliary iminodiacetic acid (HIDA) scan technique and interpretation. LC is effective for symptom resolution with low complication rates, but medical management, including proton pump inhibitors, demonstrates variable success. This review highlights the need for prospective studies to refine diagnostic criteria, identify predictors of treatment success, and compare treatment strategies to improve outcomes for children with BD.</div></div>","PeriodicalId":49543,"journal":{"name":"Seminars in Pediatric Surgery","volume":"34 ","pages":"Article 151503"},"PeriodicalIF":1.4000,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Biliary dyskinesia in the pediatric population\",\"authors\":\"Sophia MV Schermerhorn ,&nbsp;Afif N. Kulaylat ,&nbsp;Donald J. Lucas\",\"doi\":\"10.1016/j.sempedsurg.2025.151503\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Biliary dyskinesia (BD) is a functional gallbladder disorder increasingly diagnosed in pediatric patients and a leading indication for laparoscopic cholecystectomy (LC). The pathophysiology remains unclear despite its prevalence, with gallbladder dysmotility and inflammation implicated. Diagnostic challenges arise from a lack of validated pediatric criteria and inconsistent hepatobiliary iminodiacetic acid (HIDA) scan technique and interpretation. LC is effective for symptom resolution with low complication rates, but medical management, including proton pump inhibitors, demonstrates variable success. This review highlights the need for prospective studies to refine diagnostic criteria, identify predictors of treatment success, and compare treatment strategies to improve outcomes for children with BD.</div></div>\",\"PeriodicalId\":49543,\"journal\":{\"name\":\"Seminars in Pediatric Surgery\",\"volume\":\"34 \",\"pages\":\"Article 151503\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2025-06-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Seminars in Pediatric Surgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1055858625000344\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"PEDIATRICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Seminars in Pediatric Surgery","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1055858625000344","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0

摘要

胆道运动障碍(BD)是一种功能性胆囊疾病,越来越多的儿童患者被诊断出来,也是腹腔镜胆囊切除术(LC)的主要指征。尽管其普遍存在,但病理生理学尚不清楚,涉及胆囊运动障碍和炎症。诊断挑战来自缺乏有效的儿科标准和不一致的肝胆亚氨基二乙酸(HIDA)扫描技术和解释。LC对缓解症状有效,并发症发生率低,但医疗管理,包括质子泵抑制剂,显示出不同的成功。本综述强调需要前瞻性研究来完善诊断标准,确定治疗成功的预测因素,并比较治疗策略以改善双相障碍儿童的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Biliary dyskinesia in the pediatric population
Biliary dyskinesia (BD) is a functional gallbladder disorder increasingly diagnosed in pediatric patients and a leading indication for laparoscopic cholecystectomy (LC). The pathophysiology remains unclear despite its prevalence, with gallbladder dysmotility and inflammation implicated. Diagnostic challenges arise from a lack of validated pediatric criteria and inconsistent hepatobiliary iminodiacetic acid (HIDA) scan technique and interpretation. LC is effective for symptom resolution with low complication rates, but medical management, including proton pump inhibitors, demonstrates variable success. This review highlights the need for prospective studies to refine diagnostic criteria, identify predictors of treatment success, and compare treatment strategies to improve outcomes for children with BD.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Seminars in Pediatric Surgery
Seminars in Pediatric Surgery PEDIATRICS-SURGERY
CiteScore
2.80
自引率
5.90%
发文量
57
审稿时长
>12 weeks
期刊介绍: Seminars in Pediatric Surgery provides current state-of-the-art reviews of subjects of interest to those charged with the surgical care of young patients. Each bimontly issue addresses a single topic with articles written by the experts in the field. Guest editors, all noted authorities, prepare each issue.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信