Lilia Bliznashka, Monica George Michail, Dalia Elsabbagh, Aulo Gelli
{"title":"在也门的一项微量营养素强化高能饼干学校供餐计划中添加牛奶的效果:一项随机对照试验。","authors":"Lilia Bliznashka, Monica George Michail, Dalia Elsabbagh, Aulo Gelli","doi":"10.1016/j.tjnut.2025.06.021","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Two billion children globally are estimated to live in conflict-affected areas. School feeding programs (SFPs) are a widely implemented safety net that supports children during and after conflict.</p><p><strong>Objectives: </strong>We evaluated the effectiveness of providing milk alongside a high-energy biscuit (HEB) SFP in Yemen on children's and caregivers' outcomes.</p><p><strong>Methods: </strong>We implemented a 2-arm longitudinal cluster-randomized controlled trial from December 2023 to May 2024. Forty-two schools in Al Mukha district were randomly assigned (1:1) to control, where children received HEBs (2 packets [100 g] daily), or milk, where children received HEBs plus a 120 mL carton of ultra-high temperature milk. Children aged 6-18 y were randomly selected for enrolment. The primary outcomes were children's dietary diversity and milk consumption. Secondary outcomes were children's cognition, learning, attendance, nutritional status, and health. Tertiary outcomes were child and caregiver mental health and household food security. We conducted intent-to-treat analysis using linear mixed-effects models accounting for clustering.</p><p><strong>Results: </strong>One thousand two hundred ninety-nine children were enrolled. After 5 mo, the intervention increased milk consumption but had no effect on dietary diversity. Children's cognition [mean difference (MD): 1.00 (95% CI: 0.40, 1.61)], literacy [MD: 1.14 (95% CI: 0.36, 1.92)], and numeracy [MD: 1.06 (95% CI: 0.46, 1.67)] scores improved. Cough symptoms declined: MD: -0.12 (95% CI: -0.2, -0.03). There were no changes in school attendance or nutritional status. The intervention reduced conduct problems in children [MD: -0.52 (95% CI: -0.97, -0.08)], severe anxiety in caregivers [MD: -0.03 (95% CI: -0.06, -0.001)], and household severe food insecurity [MD: -0.09 (95% CI: - 0.17, -0.001)].</p><p><strong>Conclusions: </strong>Adding a daily milk drink to an HEB SFP in Yemen resulted in numerous benefits for children and their families. Hybrid models to incrementally improve meal quality are feasible, acceptable, and lead to meaningful impacts. More research is needed on medium- and long-term benefits.</p><p><strong>Registration: </strong>The trial was registered with ISRCTN (ISRCTN12225603).</p>","PeriodicalId":16620,"journal":{"name":"Journal of Nutrition","volume":" ","pages":""},"PeriodicalIF":3.7000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effect of Adding Milk to a Micronutrient-Fortified High-Energy Biscuit School Feeding Programme in Yemen: A Cluster-Randomized Controlled Trial.\",\"authors\":\"Lilia Bliznashka, Monica George Michail, Dalia Elsabbagh, Aulo Gelli\",\"doi\":\"10.1016/j.tjnut.2025.06.021\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Two billion children globally are estimated to live in conflict-affected areas. School feeding programs (SFPs) are a widely implemented safety net that supports children during and after conflict.</p><p><strong>Objectives: </strong>We evaluated the effectiveness of providing milk alongside a high-energy biscuit (HEB) SFP in Yemen on children's and caregivers' outcomes.</p><p><strong>Methods: </strong>We implemented a 2-arm longitudinal cluster-randomized controlled trial from December 2023 to May 2024. Forty-two schools in Al Mukha district were randomly assigned (1:1) to control, where children received HEBs (2 packets [100 g] daily), or milk, where children received HEBs plus a 120 mL carton of ultra-high temperature milk. Children aged 6-18 y were randomly selected for enrolment. The primary outcomes were children's dietary diversity and milk consumption. Secondary outcomes were children's cognition, learning, attendance, nutritional status, and health. Tertiary outcomes were child and caregiver mental health and household food security. We conducted intent-to-treat analysis using linear mixed-effects models accounting for clustering.</p><p><strong>Results: </strong>One thousand two hundred ninety-nine children were enrolled. After 5 mo, the intervention increased milk consumption but had no effect on dietary diversity. Children's cognition [mean difference (MD): 1.00 (95% CI: 0.40, 1.61)], literacy [MD: 1.14 (95% CI: 0.36, 1.92)], and numeracy [MD: 1.06 (95% CI: 0.46, 1.67)] scores improved. Cough symptoms declined: MD: -0.12 (95% CI: -0.2, -0.03). There were no changes in school attendance or nutritional status. The intervention reduced conduct problems in children [MD: -0.52 (95% CI: -0.97, -0.08)], severe anxiety in caregivers [MD: -0.03 (95% CI: -0.06, -0.001)], and household severe food insecurity [MD: -0.09 (95% CI: - 0.17, -0.001)].</p><p><strong>Conclusions: </strong>Adding a daily milk drink to an HEB SFP in Yemen resulted in numerous benefits for children and their families. 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引用次数: 0
摘要
背景:全球估计有20亿儿童生活在受冲突影响的地区。学校供餐计划是一个广泛实施的安全网,在冲突期间和冲突后为儿童提供支持。目的:我们评估了在也门提供牛奶和高能量饼干(HEBs) SFP对儿童和照顾者结果的有效性。方法:我们于2023年12月至2024年5月实施了一项双臂纵向集群随机对照试验。Al Mukha区的42所学校被随机(1:1)分配到:对照组,孩子们接受heb(每天2包(100克)),或牛奶,孩子们接受heb和120毫升的超高温牛奶。随机选择6-18岁的儿童参与研究。主要结果是儿童的饮食多样性和牛奶消费量。次要结局是儿童的认知、学习、出勤、营养状况和健康。第三指标是儿童和照顾者的心理健康,以及家庭食品安全。我们使用考虑聚类的线性混合效应模型进行了意向治疗分析。结果:1299名儿童入组。5个月后,干预增加了牛奶消费量,但对饮食多样性没有影响。儿童的认知[平均差异(MD) 1.00 (95% CI 0.40, 1.61)]、读写[1.14(0.36,1.92)]和计算[1.06(0.46,1.67)]得分均有改善。咳嗽症状下降:-0.12(-0.2,-0.03)。学校出勤率和营养状况没有变化。干预减少了儿童的行为问题[-0.52(-0.97,-0.08)],照顾者的严重焦虑[-0.03(-0.06,-0.001)]和家庭严重的食品不安全[-0.09(-0.17,-0.001)]。结论:在也门,每天在HEB SFP中添加牛奶饮料给儿童及其家庭带来了许多好处。逐步提高膳食质量的混合模型是可行的,可接受的,并产生有意义的影响。需要对中期和长期效益进行更多的研究。注册:该试验在ISRCTN注册(ISRCTN12225603)。
Effect of Adding Milk to a Micronutrient-Fortified High-Energy Biscuit School Feeding Programme in Yemen: A Cluster-Randomized Controlled Trial.
Background: Two billion children globally are estimated to live in conflict-affected areas. School feeding programs (SFPs) are a widely implemented safety net that supports children during and after conflict.
Objectives: We evaluated the effectiveness of providing milk alongside a high-energy biscuit (HEB) SFP in Yemen on children's and caregivers' outcomes.
Methods: We implemented a 2-arm longitudinal cluster-randomized controlled trial from December 2023 to May 2024. Forty-two schools in Al Mukha district were randomly assigned (1:1) to control, where children received HEBs (2 packets [100 g] daily), or milk, where children received HEBs plus a 120 mL carton of ultra-high temperature milk. Children aged 6-18 y were randomly selected for enrolment. The primary outcomes were children's dietary diversity and milk consumption. Secondary outcomes were children's cognition, learning, attendance, nutritional status, and health. Tertiary outcomes were child and caregiver mental health and household food security. We conducted intent-to-treat analysis using linear mixed-effects models accounting for clustering.
Results: One thousand two hundred ninety-nine children were enrolled. After 5 mo, the intervention increased milk consumption but had no effect on dietary diversity. Children's cognition [mean difference (MD): 1.00 (95% CI: 0.40, 1.61)], literacy [MD: 1.14 (95% CI: 0.36, 1.92)], and numeracy [MD: 1.06 (95% CI: 0.46, 1.67)] scores improved. Cough symptoms declined: MD: -0.12 (95% CI: -0.2, -0.03). There were no changes in school attendance or nutritional status. The intervention reduced conduct problems in children [MD: -0.52 (95% CI: -0.97, -0.08)], severe anxiety in caregivers [MD: -0.03 (95% CI: -0.06, -0.001)], and household severe food insecurity [MD: -0.09 (95% CI: - 0.17, -0.001)].
Conclusions: Adding a daily milk drink to an HEB SFP in Yemen resulted in numerous benefits for children and their families. Hybrid models to incrementally improve meal quality are feasible, acceptable, and lead to meaningful impacts. More research is needed on medium- and long-term benefits.
Registration: The trial was registered with ISRCTN (ISRCTN12225603).
期刊介绍:
The Journal of Nutrition (JN/J Nutr) publishes peer-reviewed original research papers covering all aspects of experimental nutrition in humans and other animal species; special articles such as reviews and biographies of prominent nutrition scientists; and issues, opinions, and commentaries on controversial issues in nutrition. Supplements are frequently published to provide extended discussion of topics of special interest.