Xiaomeng Shi, Lei Jiao, Peipei Zong, Xiangkun Jia, Chengjie Chen, Nana Guo, Yanling Zhai, Zhijun Zhu, Xiaoquan Lu
{"title":"在增塑剂的电化学发光感应中,单原子钴位点有效活化H2O2并增强氧耐受性。","authors":"Xiaomeng Shi, Lei Jiao, Peipei Zong, Xiangkun Jia, Chengjie Chen, Nana Guo, Yanling Zhai, Zhijun Zhu, Xiaoquan Lu","doi":"10.1002/smll.202504692","DOIUrl":null,"url":null,"abstract":"<p><p>Electrochemiluminescence (ECL) based on luminol-H<sub>2</sub>O<sub>2</sub> systems presents significant potential for the accurate and reliable biosensing. However, owing to the overlap of the potential windows for activating H<sub>2</sub>O<sub>2</sub> and dissolved O<sub>2</sub> leads to competitive reactions, which presents a significant challenge for the selective ECL sensing. Herein, single atom Co sites on nitrogen-doped hierarchically porous carbon (Co-NC SAs) as co-reaction accelerators can efficiently activate H<sub>2</sub>O<sub>2</sub> to generate reactive oxygen species for oxidation of luminol and thus achievement of enhanced ECL emission. Meanwhile, Co-NC SAs exhibits a greater tolerance to dissolved O<sub>2</sub> compared to other SAs, thereby enhancing the selectivity for the activation of H<sub>2</sub>O<sub>2</sub>. Besides, based on the inhibition effect of plasticizers toward proposed ECL platform, a three-channel sensor array is constructed to distinguish and simultaneously detect five plasticizers with high sensitivity. More importantly, this work provides new insights into the design of highly active and selective co-reaction accelerators, also rendering a promising technique for environmental monitoring against trace plasticizers.</p>","PeriodicalId":228,"journal":{"name":"Small","volume":" ","pages":"e2504692"},"PeriodicalIF":13.0000,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Single-Atom Cobalt Sites Efficient Activation of H<sub>2</sub>O<sub>2</sub> With Enhanced O<sub>2</sub> Tolerance for Electrochemiluminescence Sensing of Plasticizers.\",\"authors\":\"Xiaomeng Shi, Lei Jiao, Peipei Zong, Xiangkun Jia, Chengjie Chen, Nana Guo, Yanling Zhai, Zhijun Zhu, Xiaoquan Lu\",\"doi\":\"10.1002/smll.202504692\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Electrochemiluminescence (ECL) based on luminol-H<sub>2</sub>O<sub>2</sub> systems presents significant potential for the accurate and reliable biosensing. However, owing to the overlap of the potential windows for activating H<sub>2</sub>O<sub>2</sub> and dissolved O<sub>2</sub> leads to competitive reactions, which presents a significant challenge for the selective ECL sensing. Herein, single atom Co sites on nitrogen-doped hierarchically porous carbon (Co-NC SAs) as co-reaction accelerators can efficiently activate H<sub>2</sub>O<sub>2</sub> to generate reactive oxygen species for oxidation of luminol and thus achievement of enhanced ECL emission. Meanwhile, Co-NC SAs exhibits a greater tolerance to dissolved O<sub>2</sub> compared to other SAs, thereby enhancing the selectivity for the activation of H<sub>2</sub>O<sub>2</sub>. Besides, based on the inhibition effect of plasticizers toward proposed ECL platform, a three-channel sensor array is constructed to distinguish and simultaneously detect five plasticizers with high sensitivity. More importantly, this work provides new insights into the design of highly active and selective co-reaction accelerators, also rendering a promising technique for environmental monitoring against trace plasticizers.</p>\",\"PeriodicalId\":228,\"journal\":{\"name\":\"Small\",\"volume\":\" \",\"pages\":\"e2504692\"},\"PeriodicalIF\":13.0000,\"publicationDate\":\"2025-07-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Small\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://doi.org/10.1002/smll.202504692\",\"RegionNum\":2,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Small","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1002/smll.202504692","RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Single-Atom Cobalt Sites Efficient Activation of H2O2 With Enhanced O2 Tolerance for Electrochemiluminescence Sensing of Plasticizers.
Electrochemiluminescence (ECL) based on luminol-H2O2 systems presents significant potential for the accurate and reliable biosensing. However, owing to the overlap of the potential windows for activating H2O2 and dissolved O2 leads to competitive reactions, which presents a significant challenge for the selective ECL sensing. Herein, single atom Co sites on nitrogen-doped hierarchically porous carbon (Co-NC SAs) as co-reaction accelerators can efficiently activate H2O2 to generate reactive oxygen species for oxidation of luminol and thus achievement of enhanced ECL emission. Meanwhile, Co-NC SAs exhibits a greater tolerance to dissolved O2 compared to other SAs, thereby enhancing the selectivity for the activation of H2O2. Besides, based on the inhibition effect of plasticizers toward proposed ECL platform, a three-channel sensor array is constructed to distinguish and simultaneously detect five plasticizers with high sensitivity. More importantly, this work provides new insights into the design of highly active and selective co-reaction accelerators, also rendering a promising technique for environmental monitoring against trace plasticizers.
期刊介绍:
Small serves as an exceptional platform for both experimental and theoretical studies in fundamental and applied interdisciplinary research at the nano- and microscale. The journal offers a compelling mix of peer-reviewed Research Articles, Reviews, Perspectives, and Comments.
With a remarkable 2022 Journal Impact Factor of 13.3 (Journal Citation Reports from Clarivate Analytics, 2023), Small remains among the top multidisciplinary journals, covering a wide range of topics at the interface of materials science, chemistry, physics, engineering, medicine, and biology.
Small's readership includes biochemists, biologists, biomedical scientists, chemists, engineers, information technologists, materials scientists, physicists, and theoreticians alike.